“…BACKGROUND: Outbreaks of invasive pneumococcal disease (IPD) typically occur within institutions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Anti-retroviral treatment (ART) of HIV-infected individuals reduces their risk of invasive pneumococcal disease (IPD), however, it remains 20- to 40-fold greater compared with age-matched general population. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…KHDSS data have been used to define the incidence of hospital presentation with childhood infectious diseases (e.g. rotavirus diarrhoea, pneumococcal disease), to test the association between genetic risk factors (e.g. thalassaemia and sickle cell disease) and infectious diseases, to define the community prevalence of chronic diseases (e.g. epilepsy), to evaluate access to health care and to calculate the operational effectiveness of major public health interventions (e.g. conjugate Haemophilus influenzae type b vaccine). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…PURPOSE: Methods for quick and reliable detection of Streptococcus pneumoniae are needed for the diagnosis of pneumococcal disease and vaccine studies. This study aimed to show that sequential multiplex polymerase chain reaction (PCR) is more efficient than conventional culture in achieving S. pneumoniae-positive results. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This clinical spectrum from colonization to invasive pneumococcal disease (IPD) appears to depend on the pneumococcal capsular serotype rather than the genetic background. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: We performed a systematic review of English literature published from 1994 to 2010 on the effects of PCV dosing schedules on immunogenicity, nasopharyngeal carriage, invasive pneumococcal disease and pneumonia. Data were independently double abstracted and cleaned for analysis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CPP was a more common manifestation of pneumococcal disease among older (>2 years old) than younger children. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…After the introduction of these vaccines the incidence of invasive pneumococcal disease (IPD) due to vaccine types (VTs) declined markedly in children aged 0–2 years; however, cases among infants too young to be protected by vaccination have not been studied in detail. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…OBJECTIVE: Despite CD4(+) count restoration and viral load suppression with antiretroviral therapy (ART), HIV-infected children remain at increased risk of life-threatening infections including invasive pneumococcal disease (IPD). We therefore investigated whether persistent susceptibility to IPD following ART is associated with incomplete recovery of B-cell function. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Competitive interactions between Streptococcus pneumoniae strains during host colonization could influence the serotype distribution in nasopharyngeal carriage and pneumococcal disease. We evaluated the competitive fitness of strains of serotypes 6B, 14, 19A, 19F, 23F, and 35B in a mouse model of multiserotype carriage. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Vaccination coverage in Denmark is approximately 90 %.The aim of this study was to present multilocus sequence typing (MLST) profiles of Streptococcus pneumoniae isolates from Danish infants (0–90 days) with invasive pneumococcal disease (IPD) in the period 2003–2013. FINDINGS: 32 IPD isolates were investigated for their MLST profiles. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Malaria control and the introduction of vaccines against Haemophilus influenzae type b and pneumococcal disease are contributing to improved child survival in Africa. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…There is also an increased risk of invasive pneumococcal disease in COPD. The underlying mechanisms are not fully understood but include impaired mucociliary clearance and structural remodeling of the airways. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Streptococcus pneumoniae can cause a wide spectrum of disease, including invasive pneumococcal disease (IPD). From 2005 to 2009 an outbreak of IPD occurred in Western Canada, caused by a S. pneumoniae strain with multilocus sequence type (MLST) 289 and serotype 5. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Single nucleotide polymorphisms (SNPs) in the NFKBIZ gene, encoding the transcription factor IκBζ, are associated with increased susceptibility to invasive pneumococcal disease. We hence analyzed how IκBζ might regulate inflammatory responses to pneumococcal infection. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Out of the twenty-four diseases assessed with Australian data, our nowcasting results highlighted promise for two diseases of international concern, Ross River virus and pneumococcal disease.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: In middle-income countries, vaccines against pneumococcal disease, rotavirus, and human papilloma virus are in general more costly, not necessarily cost saving, and less consistently cost-effective than earlier generation vaccines against measles, diphtheria, tetanus, and pertussis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These findings have implications for invasive pneumococcal disease surveillance as well as studies investigating vaccine impact.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…After the introduction of conjugate vaccines, a change in the epidemiology of the serotypes causing invasive pneumococcal disease has been observed making the surveillance of circulating serotypes especially relevant. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Postlicensure PCV13 effectiveness studies against serotype 3 invasive pneumococcal disease (IPD) in children have shown inconsistent results.  …”
Enlace del recurso
Enlace del recurso
Enlace del recurso