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861por Nasereddin, Abedelmajeed, Shtayeh, Issa, Ramlawi, Asad, Salman, Nisreen, Salem, Ibrahim, Abdeen, Ziad“…Any or all of these might impinge on the type and efficacy of the pneumococcal conjugate vaccines and antibiotics to be used for prevention and treatment of pneumococcal disease in the country.…”
Publicado 2013
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862“…The five most common serotypes in sSA are among the top seven serotypes that cause invasive pneumococcal disease in children globally. These serotypes are covered by the two PCVs recommended for routine childhood immunization by the WHO. …”
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863“…Applying a concise predictive model, we present a ready-to-use quantitative tool to investigate the implications of serotype replacement on the net effectiveness of vaccination against invasive pneumococcal disease (IPD) and to guide in the selection of optimal vaccine serotype compositions. …”
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864por Janoir, Claire, Cohen, Robert, Levy, Corinne, Bingen, Edouard, Lepoutre, Agnès, Gutmann, Laurent, Varon, Emmanuelle“…In France, the use of the 7-valent pneumococcal conjugate vaccine (PCV7) lead to an overall significant decrease in PCV7 invasive pneumococcal disease (IPD) incidence. However, the decrease in vaccine serotype prevalence was partially counterbalanced by the serotype replacement phenomenon. …”
Publicado 2014
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865por Wagner, Abram L., Sun, Xiaodong, Montgomery, JoLynn P., Huang, Zhuoying, Boulton, Matthew L.“…CONCLUSION: Low vaccination coverage and extremely low levels of timely dose 1 vaccination indicate that current vaccination efforts are inadequate to reduce the burden of Hib and pneumococcal disease among Chinese children, especially infants. …”
Publicado 2014
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866“…Therefore, pneumococcal diseases prevention became a public health priority. …”
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867por Shiramoto, Masanari, Irie, Shin, Juergens, Christine, Yamaji, Masako, Tamai, Satoshi, Aizawa, Masakazu, Belanger, Todd, Gruber, William C, Scott, Daniel A, Schmoele-Thoma, Beate“…The unanticipated higher immune responses observed in the older age group in the Japanese study are of interest and of potential benefit given the higher incidence of pneumococcal disease in older adults. PCV13 was well tolerated and safe.…”
Publicado 2014
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868por Keller, Lance E., Friley, Jessica, Dixit, Cheshil, Nahm, Moon H., McDaniel, Larry S.“…Expression of PspK in an avirulent NESp mediated the progression to pneumococcal disease. Genetic exchange between pneumococci may allow dissemination of PspK, increasing the potential of NESp disease. …”
Publicado 2014
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869“…BACKGROUND: Streptococcus pneumoniae is one major cause of pneumonia in human and contains various virulence factors that contribute to pathogenesis of pneumococcal disease. This study investigated the role of pneumolysin, Ply, in facilitating S. pneumoniae invasion into the host blood stream. …”
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870“…BACKGROUND: Elderly in several European countries are currently being vaccinated against influenza and pneumococcal disease, and various reasons have been put forward to expand these programs. …”
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871por Cremers, Amelieke J. H., Mobegi, Fredrick M., de Jonge, Marien I., van Hijum, Sacha A. F. T., Meis, Jacques F., Hermans, Peter W. M., Ferwerda, Gerben, Bentley, Stephen D., Zomer, Aldert L.“…Little is known however about pneumococcal population genomics in adult invasive pneumococcal disease (IPD) under vaccine pressure. We sequenced and serotyped 349 strains of S. pneumoniae isolated from IPD patients in Nijmegen between 2001 and 2011. …”
Publicado 2015
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872por Jiang, Yiling, Gervais, Frédéric, Gauthier, Aline, Baptiste, Charles, Martinon, Prescilla, Bresse, Xavier“…A change has been witnessed in the incidence of pneumococcal diseases in adults: the incidence of invasive pneumococcal disease (IPD) of serotypes covered by PCV decreased, and serotypes not covered by PCV increased. …”
Publicado 2015
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873por Balaji, V., Jayaraman, Ranjith, Verghese, Valsan Philip, Baliga, P.R., Kurien, T.“…METHODS: Children aged less than five, who were suspected for invasive pneumococcal disease were included in the study and their sterile body fluids were investigated for the presence of S. pneumoniae. …”
Publicado 2015
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874por Prins-van Ginkel, Annemarijn C., Berbers, Guy A. M., Grundeken, Lucienne H., Tcherniaeva, Irina, Wittenberns, Jelle I., Elberse, Karin, Mollema, Liesbeth, de Melker, Hester E., Knol, Mirjam J.“…INTRODUCTION: Introduction of pneumococcal conjugate vaccines (PCVs) for infants decreased overall invasive pneumococcal disease (IPD), while non-vaccine serotype IPD increased. …”
Publicado 2016
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875“…Streptococcus pneumoniae colonization of the nasopharynx (NP) is a prerequisite for invasive pneumococcal disease (IPD). The marked reduction in IPD that followed the routine use of pneumococcal polysaccharide conjugate vaccines (PCVs) has been linked to reduced NP colonization with vaccine-included serotypes (STs), with the caveat that PCVs are less effective against pneumonia than against IPD. …”
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876“…Pneumolysin is a cholesterol-dependent cytolysin (CDC) toxin that forms lytic pores in host membranes and mediates pneumococcal disease pathogenesis by modulating inflammatory responses. …”
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877por Horácio, Andreia N., Silva-Costa, Catarina, Diamantino-Miranda, Jorge, Lopes, Joana P., Ramirez, Mario, Melo-Cristino, José“…Among the 1660 isolates recovered from invasive pneumococcal disease (IPD) in adults (> = 18 yrs) in 2008–2011, a random sample of ≥50% of each serotype (n = 871) was chosen for MLST analysis and evaluation for the presence and type of pilus islands (PIs). …”
Publicado 2016
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878por Gibson, Edward, Begum, Najida, Sigmundsson, Birgir, Sackeyfio, Alfred, Hackett, Judith, Rajaram, Sankarasubramanian“…This study compared the economic value of pediatric immunisation programmes for influenza to those for rotavirus (RV), meningococcal disease (MD), pneumococcal disease (PD), human papillomavirus (HPV), hepatitis B (Hep B), and varicella reported in recent (2000 onwards) cost-effectiveness (CE) studies identified in a systematic review of PubMed, health technology, and vaccination databases. …”
Publicado 2016
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879por La Torre, Giuseppe, Mannocci, Alice, Colamesta, Vittoria, D’Egidio, Valeria, Sestili, Cristina, Spadea, Antonietta“…BACKGROUND: The risk of getting influenza and pneumococcal disease is higher in cancer patients, and serum antibody levels tend to be lower in patients with hematological malignancy. …”
Publicado 2016
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880por Link-Gelles, Ruth, Westreich, Daniel, Aiello, Allison E., Shang, Nong, Weber, David J., Holtzman, Corinne, Scherzinger, Karen, Reingold, Arthur, Schaffner, William, Harrison, Lee H., Rosen, Jennifer B., Petit, Susan, Farley, Monica, Thomas, Ann, Eason, Jeffrey, Wigen, Christine, Barnes, Meghan, Thomas, Ola, Zansky, Shelley, Beall, Bernard, Whitney, Cynthia G., Moore, Matthew R.“…In 2010, 13-valent pneumococcal conjugate vaccine (PCV13) was introduced in the US for prevention of invasive pneumococcal disease in children. Individual-level socioeconomic status (SES) is a potential confounder of the estimated effectiveness of PCV13 and is often controlled for in observational studies using zip code as a proxy. …”
Publicado 2016
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