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1021por Reslan, Lina, Finianos, Marc, Bitar, Ibrahim, Moumneh, Mohamad Bahij, Araj, George F., Zaghlout, Alissar, Boutros, Celina, Jisr, Tamima, Nabulsi, Malak, Kara yaccoub, Gilbert, Hamze, Monzer, Osman, Marwan, Bou Raad, Elie, Hrabak, Jaroslav, Matar, Ghassan M., Dbaibo, Ghassan“…BACKGROUND: Invasive pneumococcal disease (IPD) remains a global health problem. …”
Publicado 2021
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1022por Huang, Jiachen, Gingerich, Aaron D., Royer, Fredejah, Paschall, Amy V., Pena-Briseno, Alma, Avci, Fikri Y., Mousa, Jarrod J.“…Our results identify new human MAbs for pneumococcal disease prevention and treatment and identify epitopes on PhtD and PspA recognized by human B cells.…”
Publicado 2021
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1023por Hyams, Catherine, Amin-Chowdhury, Zahin, Fry, Norman K., North, Paul, Finn, Adam, Judge, Andrew, Ladhani, Shamez N., Williams, O. Martin“…With major shifts in serotypes causing invasive pneumococcal disease (IPD), we wanted to determine the clinical phenotype of adult septic arthritis caused by Streptococcus pneumoniae. …”
Publicado 2021
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1024por Apte, Aditi, Dayma, Girish, Naziat, Hakka, Williams, Linda, Sanghavi, Sonali, Uddin, Jamal, Kawade, Anand, Islam, Maksuda, Kar, Sanchita, Li, You, Kyaw, Moe H, Juvekar, Sanjay, Campbell, Harry, Nair, Harish, Saha, Samir K, Bavdekar, Ashish“…BACKGROUND: Nasopharyngeal pneumococcal carriage (NPC) is a prerequisite for invasive pneumococcal disease and reduced carriage of vaccine serotypes is a marker for the protection offered by the pneumococcal conjugate vaccine (PCV). …”
Publicado 2021
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1025por Higgins, Rachel A, Temple, Beth, Dai, Vo Thi Trang, Phan, Thanh V, Toan, Nguyen Trong, Spry, Leena, Toh, Zheng Quan, Nation, Monica L, Ortika, Belinda D, Uyen, Doan Y, Cheung, Yin Bun, Nguyen, Cattram D, Bright, Kathryn, Hinds, Jason, Balloch, Anne, Smith-Vaughan, Heidi, Huu, Tran Ngoc, Mulholland, Kim, Satzke, Catherine, Licciardi, Paul V“…A single dose of PCV10 in the second year of life could be considered as part of catch-up campaigns or in humanitarian crises to protect children at high-risk of pneumococcal disease.…”
Publicado 2021
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1026“…These studies included mixed patient populations: (a) pyogenic meningitis; (b) meningitis in sick or hospitalized patients with tuberculosis, acute febrile encephalopathy syndrome, septicaemia, invasive pneumococcal disease or respiratory compromise; and (c) meningitis patients with comorbidities. …”
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1027por Arends, D. W., Miellet, W. R., Langereis, J. D., Ederveen, T. H. A., van der Gaast–de Jongh, C. E., van Scherpenzeel, M., Knol, M. J., van Sorge, N. M., Lefeber, D. J., Trzciński, K., Sanders, E. A. M., Dorfmueller, H. C., Bootsma, H. J., de Jonge, M. I.“…In this study, we have provided, with high accuracy, the genetic diversity of the 19A serotype in a cohort of Dutch invasive pneumococcal disease patients and asymptomatic carriers obtained in the period from 2004 to 2016. …”
Publicado 2021
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1028por Abo Ali, Fawzia Hassan, Mahmoud, Nehal Elfawy, El-Sayed, Amr Yakout Mohamed, Abdelmaksoud, Mariam Fathy, Shata, Alaa K, Fouad, Shaimaa Hani“…Asthma is one of the most common lung diseases affecting around 300 million people worldwide and is associated with risk of serious pneumococcal disease and microbial infections. Multiple studies have attributed this to impaired innate and adaptive immunity in asthmatics. …”
Publicado 2021
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1029por Henares, Desiree, Brotons, Pedro, de Sevilla, Mariona F., Fernandez-Lopez, Ana, Hernandez-Bou, Susanna, Perez-Argüello, Amaresh, Mira, Alex, Muñoz-Almagro, Carmen, Cabrera-Rubio, Raul“…This study included three groups of children <18 years with gradual decrease of ARI severity: cases with invasive pneumococcal disease (IPD) (representative of lower respiratory tract infections and systemic infections), symptomatic controls with mild viral upper respiratory tract infections (URTI), and healthy/asymptomatic controls according to an approximate case–control ratio 1:2. …”
Publicado 2021
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1030“…This study provides a complete dataset that can be used to further analyze pneumococcal prophages, their evolutionary relationships, and their role in the pathogenesis of pneumococcal disease.…”
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1031“…METHODS: This interventional (cohort) study aimed to improve the pneumococcal vaccination rate for patients with an increased risk of pneumococcal disease by utilizing a three-pronged approach. …”
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1032por Wu, Xueqing, Zhao, Shanshan, Jiang, Yan, Xiang, Xi, Ge, Lihong, Chen, Qiong, Wang, Yanfei, Vidal, Jorge E., Yu, Yunsong“…Pneumococcal conjugate vaccines (PCVs) are considered the most effective strategy for pneumococcal disease (PD) prevention, but how a pause in PCV vaccination affects the prevalence of PD or the genetic evolution of Streptococcus pneumoniae genetic evolution is unknown. …”
Publicado 2022
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1033por Miyashita, Lisa, Shears, Rebecca, Foley, Gary, Semple, Sean, Kadioglu, Aras, Grigg, Jonathan“…This study sought to determine the effect of London Underground (LU) PM(10) on; i) pneumococcal adhesion to airway cells, and ii) susceptibility to pneumococcal disease. METHODS: A549 cells and human primary airway epithelial cells were cultured with 20 µg/mL PM(10) from the Bakerloo (B-PM(10)) and Jubilee (J-PM(10)) line platforms of Baker Street station. …”
Publicado 2022
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1034“…The estimated percentages of respondents reporting ever being vaccinated were 1.5% (95% confidence interval, CI: 1.4–1.6) for influenza, 0.6% (95% CI: 0.6–0.7) for pneumococcal disease, 1.9% (95% CI: 1.8–2.0) for typhoid and 1.9% (95% CI: 1.8–2.0) for hepatitis B. …”
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1035por Smith, Emma L, Tan, Bryan, Bastas, Alysia, Kotsanas, Despina, Dendle, Claire, Ojaimi, Samar“…Of those presenting with invasive pneumococcal disease, 78% had at least 1 predisposing condition, though only 9 patients (6%) had previously received pneumococcal vaccination. …”
Publicado 2022
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1036por Stevens, Emily J., Morse, Daniel J., Bonini, Dora, Duggan, Seána, Brignoli, Tarcisio, Recker, Mario, Lees, John A., Croucher, Nicholas J., Bentley, Stephen, Wilson, Daniel J., Earle, Sarah G., Dixon, Robert, Nobbs, Angela, Jenkinson, Howard, van Opijnen, Tim, Thibault, Derek, Wilkinson, Oliver J., Dillingham, Mark S., Carlile, Simon, McLoughlin, Rachel M., Massey, Ruth C.“…Young children are at a particularly high risk, with an estimated 3–4 million cases of severe disease and between 300 000 and 500 000 deaths attributable to pneumococcal disease each year. The haemolytic toxin pneumolysin (Ply) is a primary virulence factor for this bacterium, yet despite its key role in pathogenesis, immune evasion and transmission, the regulation of Ply production is not well defined. …”
Publicado 2022
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1037“…Background: Diabetes is an immunocompromising condition, and diabetic children should receive the 23-valent pneumococcal polysaccharide (PPSV23) vaccine as part of their preventive care because of their increased risk for invasive pneumococcal disease. This recommendation is often not followed, however, and at our institution, we discovered that a factor limiting vaccine administration was lack of knowledge about the recommendation among residents. …”
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1038por Zhou, Menglan, Wu, Lijuan, Kang, Wei, Li, Yanbing, Zhang, Ge, Zhang, Jingjia, Duan, Simeng, Li, Jin, Wang, Tong, Xu, Yingchun, Gu, Yihai“…BACKGROUND: Widespread MDR Streptococcus pneumoniae in China translates clinically into a substantial pneumococcal disease burden and related morbidity and mortality, particularly in the elderly and children. …”
Publicado 2022
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1039por Mills, Richael O., Abdullah, Mohammed R., Akwetey, Samuel A., Sappor, Dorcas C., Bolivar, Johan A., Gámez, Gustavo, van der Linden, Mark P. G., Hammerschmidt, Sven“…Preventive strategies involving the use of pneumococcal conjugate vaccines (PCVs) are known to drastically reduce pneumococcal disease. However, PCV vaccination has been plagued with serotype replacement by non-PCV serotypes. …”
Publicado 2022
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1040por Wennekes, MD, Eilers, R, Caputo, A, Gagneux-Brunon, A, Gavioli, R, Nicoli, F, Quatrehomme, MMM, Vokó, Z, Timen, A“…BACKGROUND: The COVID-19 pandemic highlighted the significance of vaccination for older adults (OA), however, more health benefits could be gained with vaccination against influenza, pneumococcal disease, herpes zoster and tetanus as their uptake remains rather low. …”
Publicado 2022
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