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  1. 1181
    “…Direct vaccine protection reduced incidence of invasive pneumococcal disease (IPD), pneumonia (PNE) and acute otitis media (AOM) in vaccinated children. …”
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    Pneumococcal Vaccination Provides Substantial Value for Money for Canadians
  2. 1182
    “…To reduce the burden of pneumococcal disease, many nations have added pneumococcal conjugate vaccines to their national immunization schedules. …”
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    Changes in Pneumonia Incidence and Infant Mortality 5 Years Following Introduction of the 13-valent Pneumococcal Conjugate Vaccine in a “3+0” Schedule in Nicaragua
  3. 1183
    “…TRIAL DESIGN: In an earlier trial, Papua New Guinean (PNG) children at high risk of pneumococcal disease were randomized to receive 0 or 3 doses of 7-valent pneumococcal conjugate vaccine (PCV7), followed by a single dose of 23-valent pneumococcal polysaccharide vaccine (PPV23) at 9 months of age. …”
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    Pneumococcal responses are similar in Papua New Guinean children aged 3-5 years vaccinated in infancy with pneumococcal polysaccharide vaccine with or without prior pneumococcal conjugate vaccine, or without pneumococcal vaccination
  4. 1184
    “…Nasopharyngeal carriage is a precursor for pneumococcal disease and can be useful for evaluating pneumococcal conjugate vaccine (PCV) impact. …”
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    Nasopharyngeal carriage of Streptococcus pneumoniae among HIV-infected and –uninfected children <5 years of age before introduction of pneumococcal conjugate vaccine in Mozambique
  5. 1185
    “…METHODS: We reviewed published recommendations on medical conditions that indicate vaccination against influenza, pneumococcal disease, meningococcal disease, hepatitis A, and hepatitis B. …”
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    Using Routine Data Sources to Feed an Immunization Information System for High-Risk Patients—A Pilot Study
  6. 1186
    “…INTRODUCTION: Invasive pneumococcal disease (IPD), caused by Streptococcus pneumoniae, is a leading cause of pneumonia, meningitis and septicaemia worldwide, with increased morbidity and mortality in HIV-infected children. …”
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    Peripheral blood RNA gene expression in children with pneumococcal meningitis: a prospective case–control study
  7. 1187
    “…Vaccination rates against influenza and pneumococcal disease improved (21.5% vs 50.8% and 21.5% vs 49.2%, respectively). …”
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    Organ damage mitigation with the Baskent Sickle Cell Medical Care Development Program (BASCARE)
  8. 1188
    “…The study will allow us to conduct a comprehensive and robust assessment of the impact of national introduction of PCV10 on pneumococcal disease in Bangladesh.…”
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    Pneumococcal Conjugate Vaccine impact assessment in Bangladesh
  9. 1189
    “…Whilst co-infection can result in invasive pneumococcal disease and systemic inflammation, the neuroinflammatory consequences of co-infection are poorly characterised. …”
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    Increased hypothalamic microglial activation after viral-induced pneumococcal lung infection is associated with excess serum amyloid A production
  10. 1190
    “…We aimed to analyze the PAgT sensitivity in a population with blood culture proven invasive pneumococcal disease (IPD) and to study its performance for the different pneumococcal serotypes. …”
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    1999. Performance of Pneumococcal Urinary Antigen Testing: Riding the Vaccination Waves?
  11. 1191
    “…The most commonly diagnosed VPDs were pertussis (31%), varicella (27%), and pneumococcal disease (10%). The vast majority (94%) of pediatricians indicated that the VPDs were not acquired outside of Canada. …”
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    2473. How Does Acquiring a Vaccine-Preventable Disease Impact Parental and Physician Responses to Vaccine Hesitancy?
  12. 1192
    por Babb, Rachelle, Pirofski, Liise-Anne
    Publicado 2018
    “…Although pneumococcal conjugate vaccines are highly effective against invasive pneumococcal disease, they are less effective against pneumonia, particularly in the elderly and those with immune deficiency. …”
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    647. Characterization and Development of Human Monoclonal Antibodies to Pneumococcal Serotype 3
  13. 1193
    por Lees, John A., Ferwerda, Bart, Kremer, Philip H. C., Wheeler, Nicole E., Serón, Mercedes Valls, Croucher, Nicholas J., Gladstone, Rebecca A., Bootsma, Hester J., Rots, Nynke Y., Wijmega-Monsuur, Alienke J., Sanders, Elisabeth A. M., Trzciński, Krzysztof, Wyllie, Anne L., Zwinderman, Aeilko H., van den Berg, Leonard H., van Rheenen, Wouter, Veldink, Jan H., Harboe, Zitta B., Lundbo, Lene F., de Groot, Lisette C. P. G. M., van Schoor, Natasja M., van der Velde, Nathalie, Ängquist, Lars H., Sørensen, Thorkild I. A., Nohr, Ellen A., Mentzer, Alexander J., Mills, Tara C., Knight, Julian C., du Plessis, Mignon, Nzenze, Susan, Weiser, Jeffrey N., Parkhill, Julian, Madhi, Shabir, Benfield, Thomas, von Gottberg, Anne, van der Ende, Arie, Brouwer, Matthijs C., Barrett, Jeffrey C., Bentley, Stephen D., van de Beek, Diederik
    Publicado 2019
    “…Genetic variation of host and pathogen is known to play a role in invasive pneumococcal disease, though to what extent is unknown. In a genome-wide association study of human and pathogen we show that human variation explains almost half of variation in susceptibility to pneumococcal meningitis and one-third of variation in severity, identifying variants in CCDC33 associated with susceptibility. …”
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    Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis
  14. 1194
    “…This study compared the likelihood of hospitalised all-cause community acquired pneumonia (CAP) in patients with certain high-risk comorbidities and a comparator group with no known risk factors for pneumococcal disease. METHODS: This retrospective cohort study interrogated data in the Hospital Episodes Statistics (HES) dataset between financial years 2012/13 and 2016/17. …”
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    The impact of certain underlying comorbidities on the risk of developing hospitalised pneumonia in England
  15. 1195
    “…BACKGROUND: Children undergoing therapy for acute lymphoblastic leukemia (ALL) are at high risk of invasive pneumococcal disease (IPD). Immunization with conjugated vaccines following chemotherapy is recommended for pediatric patients. …”
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    2699. Pneumococcal Vaccination During Chemotherapy in Children Treated for Acute Lymphoblastic Leukemia
  16. 1196
    “…This study investigated the change in genetic structures of Streptococcus pneumoniae causing invasive pneumococcal disease (IPD) in Korean children after 10- and 13-valent conjugate vaccine (PCV10 and PCV13, respectively) use. …”
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    2708. Genetic Structure of Streptococcus pneumoniae Isolated from Invasive Disease in Korea, 2014–2016
  17. 1197
    “…BACKGROUND: Increased density of nasopharyngeal (NP) pneumococcal colonization has been associated with invasive pneumococcal disease in children. However, factors that lead to increased pneumococcal density are poorly understood. …”
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    2617. Increased Nasopharyngeal Pneumococcal Density During Asymptomatic Respiratory Virus Infection Is Associated with Subsequent Development of Acute Respiratory Illness
  18. 1198
    “…INTRODUCTION: Africa harbours a high burden of pneumococcal disease, with associated high mortality rates. …”
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    Pneumococcal pneumonia and carriage in Africa before and after introduction of pneumococcal conjugate vaccines, 2000–2019: protocol for systematic review
  19. 1199
    “…However, invasive pneumococcal disease (IPD) caused by PCV13-targeted serotypes still represents an important public health problem in resource-limited countries. …”
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    Molecular serotype-specific identification of Streptococcus pneumoniae using loop-mediated isothermal amplification
  20. 1200
    “…BACKGROUND: In Canada, 13-valent pneumococcal conjugate vaccine (PCV13) is recommended in childhood, in individuals at high risk of invasive pneumococcal disease (IPD) and in healthy adults aged ≥65 years for protection against vaccine-type IPD and pneumococcal community-acquired pneumonia (pCAP). …”
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    Age-stratified burden of pneumococcal community acquired pneumonia in hospitalised Canadian adults from 2010 to 2015
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