Mostrando 1,261 - 1,280 Resultados de 1,481 Para Buscar '"pneumococcal disease"', tiempo de consulta: 0.25s Limitar resultados
  1. 1261
    “…IMPORTANCE: Streptococcus pneumoniae-associated hemolytic uremic syndrome (Sp-HUS) is a serious and underdiagnosed deadly complication of invasive pneumococcal disease. Despite the introduction of the pneumococcal vaccine, cases of Sp-HUS continue to emerge, especially in children under the age of 2. …”
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    The role of pneumococcal extracellular vesicles on the pathophysiology of the kidney disease hemolytic uremic syndrome
  2. 1262
    “…However, infections caused by isolates of non-vaccine serotypes (NVT) started spreading shortly thereafter and strains of NVT 19A have become the main cause of invasive pneumococcal disease burden worldwide. The aim of the study was to characterize serotype 19A invasive pneumococci of GPSC1/CC320 circulating in Poland before the introduction of PCV into the Polish NIP in 2017 and to compare them to isolates from other countries where PCVs were implemented much earlier than in Poland. …”
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    Highly Resistant Serotype 19A Streptococcus pneumoniae of the GPSC1/CC320 Clone from Invasive Infections in Poland Prior to Antipneumococcal Vaccination of Children
  3. 1263
    “…BACKGROUND: Although vaccination is recommended for protection against invasive pneumococcal disease, the frequency of pneumococcal pneumonia is still high worldwide. …”
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    Prime-boost-type PspA3 + 2 mucosal vaccine protects cynomolgus macaques from intratracheal challenge with pneumococci
  4. 1264
    “…The World Health Organization (WHO) prioritizes pneumococcal disease as a vaccine-preventable disease and recommends the inclusion of pneumococcal conjugate vaccines (PCV) in national immunization programs worldwide. …”
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    13-Valent pneumococcal conjugate vaccines vaccination innovative strategy in Weifang City, China: a case study
  5. 1265
    “…Overall, more evidence is required for the effectiveness of such vaccinations and their frequency, but in the meantime UK national guidelines were not being followed with a large proportion of patients remaining unvaccinated against influenza and in particular pneumococcal disease. This audit highlights the importance of local data collection, discussions around correlations influencing outcomes and publication of results to improve standards of care at a national level.…”
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    Influenza and pneumococcal vaccinations in dialysis patients in a London district general hospital
  6. 1266
    “…BACKGROUND: This study presents an analysis of 1,491 serogroup 23 and 762 serogroup 15 isolates from invasive pneumococcal disease (IPD) in children and adults before and after the general recommendation for childhood pneumococcal conjugate vaccination in Germany in July 2006. …”
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    Increase of serotypes 15A and 23B in IPD in Germany in the PCV13 vaccination era
  7. 1267
    “…The major reasons for PCV immunisations were parent awareness that pneumococcal disease could be severe and vaccines were efficacious in prevention. …”
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    A community-based cross-sectional immunisation survey in parents of primary school students
  8. 1268
    “…BACKGROUND: Invasive pneumococcal disease (IPD) is responsible for significant mortality and morbidity worldwide. …”
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    Epidemiology and outcome of sepsis in adult patients with Streptococcus pneumoniae infection in a Norwegian county 1993–2011: an observational study
  9. 1269
    “…DISCUSSION: The modest and sustained decline in the rates of hospitalisation for all-cause pneumonia in children and the reduction in proportion of pneumonia hospitalisations in children coded as pneumococcal disease in the post-PCV period should alleviate concerns that pneumococcal serotype replacement may have resulted in an increased pneumonia burden in this age group. …”
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    Pneumonia hospitalisations in Scotland following the introduction of pneumococcal conjugate vaccination in young children
  10. 1270
    “…BACKGROUND: Routine immunisation with pneumococcal conjugate vaccines (PCV7/10/13) has reduced invasive pneumococcal disease (IPD) due to vaccine serotypes significantly. …”
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    Serotype distribution of Streptococcus pneumoniae causing invasive disease in children in the post-PCV era: A systematic review and meta-analysis
  11. 1271
    “…Changes to existing recommendations for older adults, however, could cement these disparities in adult PCV13 uptake in the very communities at increased risk for pneumococcal disease. These vulnerable communities may instead benefit from targeted and tailored interventions to increase pneumococcal vaccination. …”
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    Disparities in Uptake of 13-valent Pneumococcal Conjugate Vaccine among Older Adults Following Routine Recommendation in the United States
  12. 1272
    “…BACKGROUND: Recommendations for adult pneumococcal immunization generally specify the use of PCV13 first, followed by PPSV23, when administered sequentially, for prevention of pneumococcal disease. This is supported by observations of reduced functional opsonophagocytic assay (OPA) antibody titers in subjects who received PPSV23 first compared with PCV13 first. …”
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    Sequential Administration of PCV13 Followed by PPSV23 Results in a More Robust Immune Response in PPSV23-Naïve Adults Age 60–64 Years
  13. 1273
    “…PCV impact on invasive pneumococcal disease (IPD) has been extensively reported, but less described is its impact on the burden of pneumonia, sepsis and otitis media in the hospital. …”
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    Elucidating the impact of the pneumococcal conjugate vaccine programme on pneumonia, sepsis and otitis media hospital admissions in England using a composite control
  14. 1274
    “…Evaluation of the intervention includes: awareness, use and recall of intervention materials, effects on changes in determinants of vaccination behaviour, self-reported vaccine uptake, and vaccination coverage in the intervention area (primary outcomes), as well as disease incidences (secondary outcomes) and the economic burden of influenza, pneumonia, invasive pneumococcal disease and sepsis for the healthcare system (tertiary outcomes). …”
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    Increasing influenza and pneumococcal vaccine uptake in the elderly: study protocol for the multi-methods prospective intervention study Vaccination60+
  15. 1275
    “…BACKGROUND: Pneumococcal carriage is the precursor for development of pneumococcal disease, and is also responsible for transmission of the organism from person-to-person. …”
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    Pneumococcal carriage among sickle cell disease patients in Accra, Ghana: Risk factors, serotypes and antibiotic resistance
  16. 1276
    “…INTERPRETATION: Direct and indirect effects on pneumococcal carriage post-PCV10 are likely to result in reductions in pneumococcal disease, including in infants too young to be vaccinated. …”
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    Effect of ten-valent pneumococcal conjugate vaccine introduction on pneumococcal carriage in Fiji: results from four annual cross-sectional carriage surveys
  17. 1277
    “…METHODS: We defined a case as clinically or radiographically confirmed pneumonia, positive pneumococcal urine antigen test (UAT), and no evidence of invasive pneumococcal disease in a hospitalized adult ≥18 years old residing in our surveillance areas, which overlap with active bacterial core surveillance areas representing 17,000,000 adults across the United States. …”
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    1461. Non-Invasive Pneumococcal Pneumonia in the United States, 2013–2014
  18. 1278
    “…BACKGROUND: Pneumococcal meningitis (PM) is one of invasive pneumococcal disease (IPD) and is considered as a medical emergency with notable morbidity and mortality. …”
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    327. Comparison of Clinical Outcome, Causative Serotypes, and Antimicrobial Susceptibilities Between Pneumococcal Meningitis and Pneumococcal Bacteremic Pneumonia in Adult Patients in the Republic of Korea
  19. 1279
    “…BACKGROUND: Although invasive pneumococcal disease (IPD) has declined following pneumococcal conjugate vaccines, both respiratory (R-IPD; e.g., pneumonias +/− empyema) and nonrespiratory IPD (NR-IPD) remain concerning. …”
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    1432. County-Wide Pediatric IPD Experience Following Prevnar 13 Implementation
  20. 1280
    “…A few vaccines exist to prevent pneumococcal disease in adults, including a pneumococcal polysaccharide unconjugated vaccine and a protein conjugated polysaccharide vaccine. …”
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    Human monoclonal antibodies isolated from a primary pneumococcal conjugate Vaccinee demonstrates the expansion of an antigen-driven Hypermutated memory B cell response
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