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  1. 1281
    “…However, in Spain, the interpretation of pure polysaccharide 23-valent immunization is hampered by the high endemicity of pneumococcal disease and the generalization of the 13-valent adjuvant pneumococcal vaccination. …”
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    Measurement of Typhim Vi IgG as a Diagnostic Tool to Determine Anti-polysaccharide Antibody Production Deficiency in Children
  2. 1282
    “…Our findings, in combination with the limited additional pediatric literature published to date, suggest that these low vaccination rates are likely generalizable to other geographic regions as well as other chronic illnesses in which children have increased susceptibility to pneumococcal disease (5, 6). Given these results, we recommend endocrinologists and pediatricians alike take steps to ensure adherence to the PPSV23 recommendations.…”
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    SUN-139 Pneumococcal Vaccination Rates among Pediatric Diabetics
  3. 1283
    “…BACKGROUND: Despite the high burden of pneumococcal disease, pneumococcal vaccine coverage continues to fall short of Healthy People 2020 goals. …”
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    Impact of a guideline-based best practice alert on pneumococcal vaccination rates in adults in a primary care setting
  4. 1284
    “…BACKGROUND: In Colombia, clinical characteristics related to invasive pneumococcal disease (IPD) and circulating pneumococcal serotypes (ST) in adults are scarce. …”
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    1628. Clinical, Epidemiological and Microbiological Characterization of Invasive Streptococcus pneumoniae Disease in Hospitalized Adults from 5 Tertiary Hospitals in Bogotá, Colombia: A Descriptive Study
  5. 1285
    “…Pneumococcal disease remains a public health priority worldwide. …”
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    A Phase II Trial of Safety, Tolerability and Immunogenicity of V114, a 15-Valent Pneumococcal Conjugate Vaccine, Compared With 13-Valent Pneumococcal Conjugate Vaccine in Healthy Infants
  6. 1286
    por Gladstone, Rebecca A., Lo, Stephanie W., Goater, Richard, Yeats, Corin, Taylor, Ben, Hadfield, James, Lees, John A., Croucher, Nicholas J., van Tonder, Andries J., Bentley, Leon J., Quah, Fu Xiang, Blaschke, Anne J., Pershing, Nicole L., Byington, Carrie L., Balaji, Veeraraghavan, Hryniewicz, Waleria, Sigauque, Betuel, Ravikumar, K.L., Almeida, Samanta Cristine Grassi, Ochoa, Theresa J., Ho, Pak Leung, du Plessis, Mignon, Ndlangisa, Kedibone M., Cornick, Jennifer E., Kwambana-Adams, Brenda, Benisty, Rachel, Nzenze, Susan A., Madhi, Shabir A., Hawkins, Paulina A., Pollard, Andrew J., Everett, Dean B., Antonio, Martin, Dagan, Ron, Klugman, Keith P., von Gottberg, Anne, Metcalf, Benjamin J., Li, Yuan, Beall, Bernard W., McGee, Lesley, Breiman, Robert F., Aanensen, David M., Bentley, Stephen D.
    Publicado 2020
    “…Knowledge of pneumococcal lineages, their geographic distribution and antibiotic resistance patterns, can give insights into global pneumococcal disease. We provide interactive bioinformatic outputs to explore such topics, aiming to increase dissemination of genomic insights to the wider community, without the need for specialist training. …”
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    Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates
  7. 1287
    “…As S. pneumoniae colonization of the pharynx predisposes to pneumonia and invasive pneumococcal disease (IPD) caused by the colonizing serotypes, identification of the nasopharyngeal (NP) serotypes can be a surrogate to the invasive serotypes. …”
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    Serotypes and Antimicrobial Susceptibility of Nasopharyngeal Isolates of Streptococcus pneumoniae from Children Less Than 5 Years Old in Egypt
  8. 1288
    “…BACKGROUND: Pneumococcal nasopharyngeal colonization (PNC) generally precedes pneumococcal disease. The purpose of this study was to determine the prevalence of PNC and to identify the pneumococcal serotypes circulating among Bhutanese children under five years of age admitted with clinical pneumonia, before the introduction of pneumococcal conjugate vaccine (PCV13) in the country. …”
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    Pneumococcal nasopharyngeal carriage among Bhutanese children hospitalized with clinical pneumonia: serotypes and viral co-infection
  9. 1289
    “…BACKGROUND: Invasive pneumococcal disease (IPD) remains prevalent despite the use of conjugate vaccines over the past 20 years. …”
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    1242. Safety and Immunogenicity of Novel 24-Valent Pneumococcal Vaccine in Healthy Adults
  10. 1290
    “…OBJECTIVES: The aim of this study was to investigate the trends in serotypes and in vitro antimicrobial susceptibility of Streptococcus pneumoniae causing adult invasive pneumococcal disease (IPD) to dalbavancin, telavancin, tedizolid, eravacycline, omadacycline and other comparator antibiotics from 2017–2020 following implementation of the 13-valent pneumococcal conjugate vaccine (PCV-13) and during the COVID-19 (coronavirus disease 2019) pandemic. …”
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    National surveillance of antimicrobial susceptibilities to dalbavancin, telavancin, tedizolid, eravacycline, omadacycline and other comparator antibiotics and serotype distribution of invasive Streptococcus pneumoniae isolates in adults: results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART) programme in 2017–2020
  11. 1291
    “…BACKGROUND: The most common underlying medical condition among children ≥ 5 years of age with invasive pneumococcal disease is asthma. How asthma affects pneumococcal colonization is not fully understood. …”
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    1156. Pneumococcal Colonization in Children with Persistent Asthma and without Asthma
  12. 1292
    “…Post licensure surveillance indicated early declines in serotype 3 invasive pneumococcal disease (IPD) were not sustained over time [Image: see text] METHODS: Using flow cytometry, we measured C3 and C4 deposition on serotype 3 strains from children with IPD or nasopharyngeal [NP] carriage, and analyzed by clade. …”
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    1000. Serotype 3 pneumococci evade activation of the classical complement pathway
  13. 1293
    “…BACKGROUND: Despite the widespread use of pneumococcal conjugate vaccines, particularly in children, an important burden of pneumococcal disease remains in older adults. The acquisition and transmission rates of pneumococcus between older adults have not been well characterized. …”
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    1321. Acquisition and Transmission of Streptococcus pneumoniae in Individuals Over the Age of 60 Years Residing in New Haven, CT, USA
  14. 1294
    “…BACKGROUND: Patients living with HIV (PLHIV) are prone to invasive pneumococcal disease. The 13-valent conjugated pneumococcal vaccine (PCV13) is currently recommended for all PLHIV, followed in most guidelines by a 23-valent polysaccharide pneumococcal vaccine. …”
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    Single-Dose 13-Valent Conjugate Pneumococcal Vaccine in People Living With HIV – Immunological Response and Protection
  15. 1295
    “…IMPORTANCE: Following routine use of 13-valent pneumococcal conjugate vaccine (PCV13) in children in 2010, invasive pneumococcal disease rates have decreased substantially in children and adults. …”
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    Incidence and Estimated Vaccine Effectiveness Against Hospitalizations for All-Cause Pneumonia Among Older US Adults Who Were Vaccinated and Not Vaccinated With 13-Valent Pneumococcal Conjugate Vaccine
  16. 1296
    “…BACKGROUND: Pneumococcal disease is a leading cause of bacterial pneumonia and invasive bacterial disease among children globally. …”
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    Effect of childhood vaccination and antibiotic use on pneumococcal populations and genome-wide associations with disease among children in Nepal: an observational study
  17. 1297
    “…MAIN OUTCOMES AND MEASURES: The main outcomes were the incidence rate of the following VPIs in SOT recipients: hepatitis A and B, diphtheria, Haemophilus influenzae infection, influenza, measles, mumps, pertussis, pneumococcal disease, poliomyelitis, meningococcal disease, rubella, tetanus, tick-borne encephalitis, and varicella zoster virus infection. …”
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    Vaccine-Preventable Infections Among Solid Organ Transplant Recipients in Switzerland
  18. 1298
    “…In SSA, serotype 1 pneumococci particularly the endemic ST217 clone, causes majority of the pneumococcal disease burden. To understand the evolution of the virulent ST217 clone, we analysed ST217 whole genomes from isolates sampled from African and Asian countries. …”
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    Understanding pneumococcal serotype 1 biology through population genomic analysis
  19. 1299
    “…BACKGROUND: In many industrialized countries routine vaccination with the 23-valent pneumococcal polysaccharide vaccine (PPSV-23) is recommended to prevent pneumococcal disease in the elderly. However, vaccine-induced immunity wanes after a few years, and there are controversies around revaccination with PPSV-23. …”
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    Effectiveness, immunogenicity and safety of 23-valent pneumococcal polysaccharide vaccine revaccinations in the elderly: a systematic review
  20. 1300
    “…BACKGROUND: This trial (ClinicalTrials.gov identifier NCT00839254), nested within a cluster-randomized double-blind invasive pneumococcal disease effectiveness study in Finland (ClinicalTrials.gov identifier NCT00861380), assessed the effectiveness of the 10-valent pneumococcal polysaccharide nontypeable Haemophilus influenzae protein D–conjugated vaccine (PHiD-CV or PCV10) against bacterial nasopharyngeal carriage and acute otitis media (AOM). …”
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    Effectiveness of the 10-Valent Pneumococcal Nontypeable Haemophilus influenzae Protein D–Conjugated Vaccine (PHiD-CV) Against Carriage and Acute Otitis Media—A Double-Blind Randomized Clinical Trial in Finland
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