Mostrando 1,301 - 1,320 Resultados de 1,481 Para Buscar '"pneumococcal disease"', tiempo de consulta: 1.31s Limitar resultados
  1. 1301
    “…Given that colonization with PCV10 serotypes is associated with greater risk for invasive disease than colonization with other serotypes, successful PCV10 introduction in Kenya is likely to have a substantial impact in reducing vaccine-type pneumococcal disease and drug-resistant pneumococcal infection. …”
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  2. 1302
    “…BACKGROUND: The implementation of pneumococcal conjugate vaccination (PCV) in children with the 7-valent and 13-valent PCV in 2000 and 2010, respectively, has reduced the incidence of pneumococcal disease, nasopharyngeal carriage and changed the epidemiology of S. pneumoniae serotypes (STs). …”
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  3. 1303
    “…BACKGROUND: The aim of the present study was to assess the prevalence and characteristics of S. pneumoniae serotype 19A isolates from invasive and non-invasive pneumococcal disease (IPD) in children, before and after the introduction of pneumococcal conjugate vaccines (PCVs) in Greece. …”
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  4. 1304
    “…BACKGROUND: This study investigated the genetic structure of Streptococcus pneumoniae isolates from invasive pneumococcal disease (IPD) in Korean children after national immunization program (NIP) of extended-valency pneumococcal conjugate vaccines (PCVs) in Korea from 2014 to 2017. …”
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  5. 1305
    “…Invasive pneumococcal disease (IPD) has greatly decreased since implementation in the U.S. of the 7 valent conjugate vaccine (PCV7) in 2000 and 13 valent conjugate vaccine (PCV13) in 2010. …”
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  6. 1306
    “…We conducted a mathematical modelling study to investigate the potential impact of a 1+1 (3, 12 month) schedule on invasive pneumococcal disease (IPD) and pneumococcal community-acquired pneumonia (CAP). …”
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  7. 1307
    “…BACKGROUND: In healthy adults aged ≥65 years, direct immunization with the 13-valent pneumococcal conjugate vaccine (PCV13) was shown effective at preventing vaccine-type pneumococcal community-acquired pneumonia (pCAP) and invasive pneumococcal disease (IPD). Although PCV13 was licensed for use in Canadian adults aged >50 years, it was recommended for immunocompromised individuals who are at highest risk of IPD. …”
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  8. 1308
  9. 1309
    “…CONCLUSION: Based on the robust immune responses and comparability to licensed pneumococcal vaccines, as well as bridging to the younger age group, these data support that PCV20 will be protective against pneumococcal disease due to the 20 serotypes in adults. DISCLOSURES: Charu Sabharwal, MD, MPH, Pfizer (Employee, Shareholder) Xia Xu, PhD, Pfizer (Employee, Shareholder) Vani Sundaraiyer, PhD, MS, Pfizer (Independent Contractor) Yahong Peng, PhD, Pfizer (Employee, Shareholder) Lisa Moyer, BS, Pfizer (Employee, Shareholder) Michael W. …”
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  10. 1310
    “…BACKGROUND: Because of the number and variability of serotypes causing pneumococcal disease among different geographic regions, age groups, and environmental backgrounds, expanding serotype coverage with pneumococcal conjugate vaccines (PCVs) is a continued unmet need. …”
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  11. 1311
  12. 1312
    “…Total cases of pneumococcal disease, deaths, direct and indirect healthcare costs, and quality-adjusted life years (QALYs) gained are discounted 7% annually and modeled for each PCV. …”
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  13. 1313
  14. 1314
    “…The current pneumococcal capsular polysaccharide (PPS) conjugate vaccine (PCV13) is less effective against Streptococcus pneumoniae serotype 3 (ST3), which remains a major cause of pneumococcal disease and mortality. Therefore, dissecting structure-function relationships of human ST3 pneumococcal capsular polysaccharide (PPS3) antibodies may reveal characteristics of protective antibodies. …”
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  15. 1315
  16. 1316
    “…Emerging penicillin non-susceptible Streptococcus pneumoniae (PNSP) challenges therapy of pneumococcal disease. The aim of this study was to determine the mechanisms of antibiotic resistance among PNSP isolates by next generation sequencing. …”
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  17. 1317
    “…The medical and nonmedical cost burden of pneumococcal diseases offset with vaccination was KW44,033 million (US$33.87 million). …”
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  18. 1318
  19. 1319
    “…BACKGROUND: The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced to prevent invasive pneumococcal disease (IPD) in Western Australian (WA) Aboriginal people in 2001. …”
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  20. 1320
    “…We aimed to estimate pneumococcal serotypes associated with acute respiratory infection (ARI) and invasive pneumococcal disease (IPD) in hospitalized children in Blantyre, Malawi. …”
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