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681por Horácio, Andreia N., Silva-Costa, Catarina, Lopes, Joana P., Ramirez, Mário, Melo-Cristino, José“…Since 2010 the 13-valent pneumococcal conjugate vaccine (PCV13) replaced the 7-valent vaccine (PCV7) as the leading pneumococcal vaccine used in children through the private sector. …”
Publicado 2016
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682por Alqahtani, Amani S, Bondagji, Daniah M, Alshehari, Abdullah A, Basyouni, Mada H, Alhawassi, Tariq M, BinDhim, Nasser F, Rashid, Harunor“…The overall uptake of pneumococcal vaccine in the preceding three years was 22% (25% among “at risk” individuals) and ranged from 0% in Bahrain to 79% in Kuwait. …”
Publicado 2017
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683por Domínguez, Ángela, Ciruela, Pilar, Hernández, Sergi, García-García, Juan José, Soldevila, Núria, Izquierdo, Conchita, Moraga-Llop, Fernando, Díaz, Alvaro, F. de Sevilla, Mariona, González-Peris, Sebastià, Campins, Magda, Uriona, Sonia, Martínez-Osorio, Johanna, Solé-Ribalta, Anna, Codina, Gemma, Esteva, Cristina, Planes, Ana María, Muñoz-Almagro, Carmen, Salleras, Luis“…BACKGROUND: The 13-valent pneumococcal conjugate vaccine (PCV13) was licensed based on the results of immunogenicity studies and correlates of protection derived from randomized clinical trials of the 7-valent conjugate pneumococcal vaccine. We assessed the vaccination effectiveness (VE) of the PCV13 in preventing invasive pneumococcal disease (IPD) in children aged 7–59 months in a population with suboptimal vaccination coverage of 55%. …”
Publicado 2017
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684por Kwambana-Adams, Brenda, Hanson, Blake, Worwui, Archibald, Agbla, Schadrac, Foster-Nyarko, Ebenezer, Ceesay, Fatima, Ebruke, Chinelo, Egere, Uzochukwu, Zhou, Yanjiao, Ndukum, Maze, Sodergren, Erica, Barer, Michael, Adegbola, Richard, Weinstock, George, Antonio, Martin“…Immediate replacement of pneumococcal vaccine serotypes with non-vaccine serotypes may mitigate the impact of PCV7 on nasopharyngeal bacterial community structure and ecology.…”
Publicado 2017
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685por Bojang, Abdoulie, Kendall, Lindsay, Usuf, Effua, Egere, Uzochukwu, Mulwa, Sarah, Antonio, Martin, Greenwood, Brian, Hill, Philip C., Roca, Anna“…Carriage of S. pneumoniae did not have any effect on S. aureus carriage for any pneumococcal, vaccine-type (VT) or non-vaccine-type (NVT) carriage. …”
Publicado 2017
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686por von Hehn, Christian, Howard, Jonathan, Liu, Shifang, Meka, Ven, Pultz, Joe, Mehta, Devangi, Prada, Claudia, Ray, Soma, Edwards, Michael R., Sheikh, Sarah I.“…METHODS: In this open-label, multicenter study, patients received 3 vaccinations: (1) tetanus-diphtheria toxoid (Td) to test T-cell–dependent recall response, (2) pneumococcal vaccine polyvalent to test T-cell–independent humoral response, and (3) meningococcal (groups A, C, W-135, and Y) oligosaccharide CRM(197) conjugate to test T-cell–dependent neoantigen response. …”
Publicado 2017
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687por Nelson, Kristin N, Grijalva, Carlos G, Chochua, Sopio, Hawkins, Paulina A, Gil, Ana I, Lanata, Claudio F, Griffin, Marie R, Edwards, Kathryn M, Klugman, Keith P, Vidal, Jorge E“…We examined the effect of introduction of the 7-valent pneumococcal vaccine on Spn carriage patterns in a cohort of Peruvian children. …”
Publicado 2018
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688por Naucler, Pontus, Galanis, Ilias, Morfeldt, Eva, Darenberg, Jessica, Örtqvist, Åke, Henriques-Normark, Birgitta“…BACKGROUND: Pneumococccal conjugated pneumococcal vaccine (PCV10) and pneumococcal conjugate vaccine 13 (PCV13), are used in childhood immunization programs worldwide, but direct comparisons of impacts against invasive pneumococcal disease (IPD) in equivalent populations have not been performed. …”
Publicado 2017
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689por Kakiuchi, Satoshi, Suzuki, Motoi, Dhoubhadel, Bhim Gopal, Furumoto, Akitsugu, Ito, Hiroyuki, Matsuki, Kei, Tsuchihashi, Yoshiko, Asoh, Norichika, Yasunami, Michio, Ariyoshi, Koya, Morimoto, Konosuke“…The lack of reliable diagnostic tests for detecting vaccine serotype pneumococcal pneumonia (VTPP) remains a challenging issue in pneumococcal vaccine studies. This study assessed the performances of high-throughput nanofluidic PCR-based pneumococcal serotyping and quantification assay methods using sputum samples (the nanofluidic sputum quantitative PCR [Sp-qPCR] assay) to diagnose 13-valent pneumococcal conjugate VTPP compared with the performance of the serotype-specific urinary antigen detection (UAD) assay using urine samples. …”
Publicado 2018
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690por Shen, Hongwei, Zhu, Chunqing, Liu, Xiaorong, Ma, Dongli, Song, Chunli, Zhou, Lintao, Wang, Zuer, Ou, Yongxuan, Ma, Wen, Shi, Xianghui, Ma, Xuejun, Zhou, Yiwen“…A better prevention strategy for GBS, the introduction of pneumococcal vaccine, and incorporation of PCR methods were recommended.…”
Publicado 2019
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691por Renner, Lorna Awo, Usuf, Effua, Mohammed, Nuredin Ibrahim, Ansong, Daniel, Dankwah, Thomas, Kusah, Jonas Tettey, Owusu, Sandra Kwarteng, Awunyo, Marah, Arhin, Bernard, Addo, Yvonne, Asamoah, John, Biey, Joseph Nsiari-Muzeyi, Ndow, Peter Slyvanus, Worwui, Archibald, Senghore, Madikay, Ntsama, Bernard, Mwenda, Jason M, Diamenu, Stanley K, Adams, Brenda Kwanbana, Antonio, Martin“…The proportion of pneumococcal vaccine serotypes causing meningitis decreased from 81.3% (13 of 16) before the introduction of 13-valent PCV (2010–2012) to 40.0% (8 of 20) after its introduction (2013–2016). …”
Publicado 2019
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692por Boni-Cisse, Catherine, Jarju, Sheikh, Bancroft, Rowan E, Lepri, Nicaise A, Kone, Hamidou, Kofi, N’zue, Britoh-Mlan, Alice, Zaba, Flore Sandrine, Usuf, Effua, Ndow, Peter Sylvanus, Worwui, Archibald, Mwenda, Jason M, Biey, Joseph N, Ntsama, Bernard, Kwambana-Adams, Brenda A, Antonio, Martin“…CONCLUSIONS: Despite widespread use and high coverage of conjugate vaccines, pneumococcal vaccine serotypes and H. influenzae type b remain associated with bacterial meningitis among children aged <5 years in Côte d’Ivoire. …”
Publicado 2019
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693por Martinez-Vega, Rosario, Jauneikaite, Elita, Thoon, Koh Cheng, Chua, Hui Ying, Huishi Chua, Amanda, Khong, Wei Xin, Tan, Ban Hock, Low Guek Hong, Jenny, Venkatachalam, Indumathi, Anantharajah Tambyah, Paul, Hibberd, Martin L., Clarke, Stuart C., Ng, Oon Tek“…Invasive pneumococcal infection is a major cause of morbidity and mortality worldwide despite the availability of pneumococcal vaccines. The aim of this study was to re-evaluate the clinical syndromes, prognostic factors and outcomes for pneumococcal disease in adults and children in Singapore during the period before and after the introduction of the pneumococcal vaccine. …”
Publicado 2019
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694por Rieg, Siegbert, Bechet, Lena, Naujoks, Kai, Hromek, Julia, Lange, Berit, Juzek-Küpper, Marc-Fabian, Stete, Katarina, Müller, Matthias C, Jost, Insa, Kern, Winfried V, Theilacker, Christian“…CONCLUSIONS: With dedicated outpatient care, high uptake of pneumococcal vaccination postsplenectomy was achieved. Sepsis episodes were largely of nonpneumococcal etiology in patients who had received dedicated postsplenectomy care.…”
Publicado 2020
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695Designing self-assembled peptide nanovaccine against Streptococcus pneumoniae: An in silico strategypor Dorosti, Hesam, Eslami, Mahboobeh, Nezafat, Navid, Fadaei, Fardin, Ghasemi, Younes“…Although the pneumoniae polysaccharide vaccine (PPV) and pneumonia conjugate vaccines (PCV) are the efficient pneumococcal vaccine in children and adult groups, but the serotype replacement of S. pneumoniae strains causes the reduction in efficacy of such vaccines. …”
Publicado 2019
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696“…The use of a 23-valent polysaccharide vaccine against Streptococcus pneumoniae has been amended by a 13-valent conjugated pneumococcal vaccine originally developed for young children several years ago to overcome at least some of the limitations of the T cell-independent polysaccharide antigens, but still is only approximately 50% protective against pneumonia. …”
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697por Morton, Ben, Burr, Sarah, Jambo, Kondwani, Rylance, Jamie, Henrion, Marc Y.R., Banda, Ndaziona Peter, Nsomba, Edna, Kapumba, Blessings, Manda-Taylor, Lucinda, Masesa, Clemens, Ferrreira, Daniela, Gordon, Stephen B.“…Confirmation of pneumococcal controlled human infection model feasibility in Malawi will enable us to target pneumococcal vaccine candidates for an at-risk population who stand the most to gain from new and improved vaccine strategies.…”
Publicado 2020
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698por Kawakami, Kenji, Nakamura, Atsushi, Wakana, Akira, Folaranmi, Temitope A., Iino, Tomoharu“…The 23-valent capsular polysaccharide pneumococcal vaccine (PPSV23) was introduced in Japan’s routine immunization schedule October 2014. …”
Publicado 2019
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699por McGreevy, Sheila, McGowan, Caylin, Gillenwater, Kristin, Opole, Rebecca, Veluri, Meena, Stehle, Kim, Ramm, Bethany, Gibson, Cheryl“…There are two types of pneumococcal vaccines, one with polysaccharides from the capsule of 23 serotypes (PPSV23) and one with polysaccharides from 13 serotypes that have been conjugated to a protein (PCV13). …”
Publicado 2020
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700por Kumar, Sambuddha, Purakayastha, Debjani Ram, Kapil, Arti, Saha, Siddhartha, Dawood, Fatimah S., Das, Bimal Kumar, Amarchand, Ritvik, Kumar, Rakesh, Lafond, Kathryn E., Jain, Seema, Krishnan, Anand“…Pneumococcal detection was relatively low among children in our study community but demonstrated a diverse range of serotypes and half of these serotypes would be covered by the current formulation of 13-valent pneumococcal vaccine.…”
Publicado 2021
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