“…METHODS: A total of 22 blood cultures and 24 urine samples positive for Escherichia coli or Klebsiella pneumoniae and corresponding isolates were collected from the microbiology diagnostics laboratory. …”
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“…Microbiome data showed that coinfection significantly increased the relative abundances of Enterococcus faecalis, Enterobacter hormaechei, Citrobacter freundii, and Klebsiella pneumoniae and decreased the relative abundances of Lactobacillus reuteri and Lactobacillus murinus. …”
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“…Finally, the protection against an intraperitoneal challenge with 10(6) CFU/mouse of multi-drug resistance of Streptococcus pneumoniae ATCC49619 was investigated. Our findings showed a significant increase in the anti-PhtD and anti-rPspA sera IgG levels in the immunized group with the PhtD+rPspA formulation compared to each alone. …”
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“…The results revealed the effectiveness of the aqueous extract compared to the essential oil against Gram-negative bacteria (K. pneumoniae, A. baumannii, E. aerogenes, E. cloacae, P. fluorescence, Salmonella sp., Shigella sp., and Y. enterolitica) and candidoses (C. krusei and C. albicans). …”
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“…In 2022, 9 index CRE cases (5 Klebsiella pneumoniae carbapenemase (KPC)–producing and 4 New Delhi Metallo-β-lactamase (NDM)–producing cases) were identified within the University of Colorado Hospital (UCH) inpatient population. …”
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“…Methods: We grew methicillin-resistant and -susceptible Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae on 3D-printed disks and conducted bacterial survival assays to determine whether bacteria grow on PLA, PLACTIVE, and PUREMENT. …”
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“…While A. baumannii, K. pneumoniae, and P. aeruginosa were the common hospital acquired pathogens for co-infection and secondary pulmonary infection. …”
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“…OBJECTIVE: This research aims to identify the effect of various organic solvents such as n-hexane, ethyl acetate (EtOAc), and methanol (MeOH) on the antioxidant and antibacterial activities of Curcuma zedoaria extract, against three Gram-positive bacteria, namely Staphylococcus aureus, Bacillus subtilis, and Streptococcus pneumoniae, and three Gram-negative bacteria, namely Escherichia coli, Salmonella typhi, and Pseudomonas aeruginosa MATERIALS AND METHODS: As much as 1 kg of white turmeric rhizome (C. zedoaria) was extracted two times for 24 h using 3 l of MeOH before evaporating. …”
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“…FDC, was tested in ID-CAMHB across 44 total CDC AR-Bank carbapenem-resistant K. pneumoniae, A. baumannii, and P. aeruginosa species. 34 CDC AR-Bank Strains predominantly resistant (30/34) to Cefepime were used to assess FTB. …”
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“…Organisms with meropenem MIC >1 mg/L and Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, and Proteus mirabilis with aztreonam or ceftazidime MIC >1 mg/L were screened for β-lactamase genes by PCR and Sanger sequencing. …”
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“…Of the 39 co-infecting pathogens from ATTACK, 30 (43%) were carbapenem non-susceptible (8 PA, 21 Klebsiella pneumoniae and 1 Proteus mirabilis). Addition of durlobactam restored imipenem susceptibility to 83% (N = 25) and meropenem susceptibility to 70% (N = 21) of these isolates. …”
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“…Our goal here is to assess the effect of insertion-deletion (INDEL) mutations located in the three hotspots in KPC-2, and their impact on the efficacy of these two drug combinations [Figure: see text] METHODS: The bla(KPC-44) (ins_261_AVYTRAPNKDDKHSE), bla(KPC-80) (ins_267_PNK), bla(KPC-81) (del_173_I), bla(KPC-97) (ins_276_VNSEA), and bla(KPC-160) (del_167_LE) genes were amplified by PCR from K. pneumoniae isolates resistant to CZA. The bla(KPC-14) (del_242-243_GT) gene was obtained by mutagenesis from the bla(KPC-2) gene. …”
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“…Cases were defined as the first instance of positive culture in a county resident from a normally sterile site or urine of Escherichia coli, Klebsiella pneumoniae, or K. oxytoca resistant to ≥ 1 3rd-generation cephalosporin and nonresistant to carbapenems. …”
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“…Among 33 patients with CRE colonization on admission, the most common CRE isolated was Klebsiella pneumoniae (59% [20/34 isolates]) followed by Escherichia coli (38% [13/34 isolates]). …”
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“…Strip 1 is the topA gene specific to K. pneumoniae. Strips 2-4 are AMR genes KPC, CTX-M-15, and MecA. …”
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“…BACKGROUND: Pneumococcal infection is a vaccine-preventable illness caused by Streptococcus pneumoniae. In October 2021, the Advisory Committee on Immunization Practices updated pneumococcal vaccine guidelines in all adults >65 years and for adults 19-64 years with certain medical conditions or risk factors. …”
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“…BACKGROUND: SPR206 is a novel polymyxin derivative with potent in vitro activity against susceptible and multidrug-resistant strains of Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, and Enterobacter species. …”
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“…RESULTS: A total of 230 isolates of Streptococcus pneumoniae from sterile body fluid samples were obtained. …”
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“…The index date was the first positive culture of E. coli, E. cloacae, K. aerogenes, K. oxytoca, and/or K. pneumoniae. Patients having a CRE culture on index were included in the exposure group, and those having all CSE cultures were included in the comparator group. …”
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“…Numbers of ESBLs were 21 from E, coli and K. pneumoniae complex and MBLs were 2 from M. odoratimimus using DSTM. 4 specimens containing Proteus mirabilis (CTX-M-2) from one patient were false negative for ESBL because those were insensitive to CVA. …”
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