“…Our information-rich genotype-phenotype map reveals a multidimensional portrait of gene and cellular function.…”
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“…We then recorded the spontaneous neural activity of the engineered neuronal network, which revealed an important portrait of the engineered neuronal network–modular architecture enhances functional complexity by reducing the excessive neural correlation between spatially segregated modules. …”
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“…Au fil de la conversation se dessine alors le portrait attachant d'un homme brillant et libre, habité par un rêve, celui de comprendre, de décortiquer ce monde et de chercher la beauté de ses lois. …”
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“…Janna Levin’s absorbing account of the surprises, disappointments, achievements, and risks in this unfolding story offers a portrait of modern science that is unlike anything we’ve seen before.…”
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“…Exemplarily presented is the nearly perfect discrimination of the most important fine-grained marbles and furthermore the possibility of the intra-site discrimination of the three Carrara districts and the assignment of two portrait heads to the Carrara Torano quarries.…”
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“…We used open-ended interviews, field notes from informal conversations and observations, photographic evidence of children's literacy practices, and language portrait (LP) descriptions, to collect data. Results from an ethnographic analysis of the data revealed a whole range of negative and positive parental emotions (e.g., anxiety, loss, shame vs. enjoyment, accomplishment, and pride), in the discourse of maintaining heritage and minority languages. …”
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“…Collectively, these data depict a comprehensive portrait of lens fiber cell differentiation, while defining regulatory effectors of cell identity and cataract formation.…”
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“…In clinical scenarios, the use of biomedical sensors, devices and multi-parameter assessments is fundamental to provide a comprehensive portrait of patients’ state, in order to adapt and personalize rehabilitation interventions and support clinical decision-making. …”
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“…There is an intense interest in applying proteomics to foster an improved understanding of cancer pathogenesis, develop new tumor biomarkers for diagnosis, and early detection using proteomic portrait of samples. Oncoproteomics has the potential to revolutionize clinical practice, including cancer diagnosis and screening based on proteomic platforms as a complement to histopathology, individualized selection of therapeutic combinations that target the entire cancer-specific protein network, real-time assessment of therapeutic efficacy and toxicity, and rational modulation of therapy based on changes in the cancer protein network associated with prognosis and drug resistance. …”
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“…CONCLUSION: The results presented here provide a comprehensive, genome-wide portrait of transcripts encompassing the BvgAS regulon, while also providing data validating the long-oligonucleotide microarray described here for studying gene expression in Bordetella bronchiseptica.…”
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“…Our work presents an overall portrait of the evolution of these important genes in DNA metabolism and also provides further understanding about the early evolution of cellular organisms.…”
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“…A genome-wide quantitative portrait of each individual NFR, with their starting and ending positions, lengths, and degrees of nucleosome depletion is critical for revealing the heterogeneity of gene regulation and chromatin organization. …”
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“…Therefore, we attempted to elucidate a molecular portrait of lenalidomide-mediated cellular events in NSCLC. …”
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“…DNA-predicted hair and eye colour are consistent with Richard’s appearance in an early portrait. We calculate likelihood ratios for the non-genetic and genetic data separately, and combined, and conclude that the evidence for the remains being those of Richard III is overwhelming.…”
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“…CONCLUSION: Integrated analysis of multidimensional data from the TCGA archive allowed to draw a portrait of distinct molecular subclasses of human ccRCC and to define signatures for prognosticating disease outcome. …”
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“…By employing chemical, behavioral, and electrophysiological analyses, we provide a comprehensive portrait of the olfactory neuroethological correlates underlying fly-yeast coadaptation in two drosophilids with distinct habitats.…”
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“…Clinics are increasingly adopting gene-expression profiling to diagnose breast cancer subtype, providing an intrinsic, molecular portrait of the tumor. For example, the PAM50-based Prosigna test quantifies expression of 50 key genes to classify breast cancer subtype, and this method of classification has been demonstrated to be superior over traditional immunohistochemical methods that detect proteins, to predict risk of disease recurrence. …”
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“…These tests and the gene expression pattern grid may be useful for the identification of therapeutic targets and diagnostic or prognostic markers that are present only in subsets of cancer patients, and provide a more complete portrait of differential expression in cancer.…”
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