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  1. 1401
    “…Science. 320:1629–1631. and Dopman EB, Hartl DL. 2007. A portrait of copy-number polymorphism in Drosophila melanogaster. …”
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    Validation of Rearrangement Break Points Identified by Paired-End Sequencing in Natural Populations of Drosophila melanogaster
  2. 1402
    “…Overall, this study provides a portrait of the Y-chromosomal variation in Iran, useful for depicting a more comprehensive history of the peoples of this area as well as for reconstructing ancient migration routes. …”
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    Ancient Migratory Events in the Middle East: New Clues from the Y-Chromosome Variation of Modern Iranians
  3. 1403
    “…Previous studies have shown that based on their mRNA expression breast tumors could be divided into five subgroups (Luminal A, Luminal B, Basal, ErbB2(+) and Normal-like), each with a distinct molecular portrait. Whole genome gene expression analysis of independent sets of breast tumors reveals repeatedly the robustness of this classification. …”
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    Overrepresentation of transcription factor families in the genesets underlying breast cancer subtypes
  4. 1404
    “…A major consequence of these results is that the genetic profile of a single tissue collected at one time point should be used with caution as a faithful portrait of other tissues from the same subject or the same tissue throughout life. …”
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    Online Artículo Texto
    Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime
  5. 1405
    “…In this study, we sought a detailed portrait of the genetic variation within the β-globin cluster in a large human population panel from different geographic backgrounds. …”
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    Evolutionary Constraints in the β-Globin Cluster: The Signature of Purifying Selection at the δ-Globin (HBD) Locus and Its Role in Developmental Gene Regulation
  6. 1406
    “…The resulting transcriptomes paint an exquisite portrait of human lactation. The resulting transcriptional profiles cluster not by postpartum day, but by milk Na:K ratio, indicating that women sampled during similar postpartum time frames could be at markedly different stages of gene expression. …”
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    RNA Sequencing of the Human Milk Fat Layer Transcriptome Reveals Distinct Gene Expression Profiles at Three Stages of Lactation
  7. 1407
    “…A major consequence of these results is that the genetic profile of a single tissue collected at one time point should be used with caution as a faithful portrait of other tissues from the same subject or the same tissue throughout life. …”
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    Republished: Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime
  8. 1408
    “…An important question is whether diagnostic tumor tissue from the primary lesion offers an accurate molecular portrait of the cancer post recurrence and thus may be used for predictive diagnostic purposes for patients with relapsed, metastatic disease. …”
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    Targeted Biomarker Profiling of Matched Primary and Metastatic Estrogen Receptor Positive Breast Cancers
  9. 1409
    “…CONCLUSION: We tested the efficiency of our strategy, showing that our method is platform-independent, thus allowing the simultaneous analysis of the same sample with different NGS technologies, and providing an accurate quantitative and qualitative portrait of complex whole transcriptomes. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1471-2164-14-855) contains supplementary material, which is available to authorized users.…”
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    A platform independent RNA-Seq protocol for the detection of transcriptome complexity
  10. 1410
    “…Several studies that measured basic human values with the Portrait Values Questionnaire (PVQ) reported problems of measurement noninvariance (especially scalar noninvariance) across countries. …”
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    Comparing results of an exact vs. an approximate (Bayesian) measurement invariance test: a cross-country illustration with a scale to measure 19 human values
  11. 1411
    “…To meet the challenges of de novo assembly, multiple approaches for cross validation of findings were performed to achieve reliable assemblies of venom duct transcriptomes and to obtain a robust portrait of Terebridae venom. Phylogenetic methodology was used to identify 14 teretoxin gene superfamilies for the first time, 13 of which are unique to the Terebridae. …”
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    Molecular Diversity and Gene Evolution of the Venom Arsenal of Terebridae Predatory Marine Snails
  12. 1412
    “…The implementation of QuickGo web-services in our pipeline enable the users to carry out GO-Slim analysis, whereas the integration of PORTRAIT (Prediction of transcriptomic non coding RNA (ncRNA) by ab initio methods) helps to identify the non coding RNAs and their regulatory role in transcriptome. …”
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    Transcriptator: An Automated Computational Pipeline to Annotate Assembled Reads and Identify Non Coding RNA
  13. 1413
    “…CONCLUSIONS: Our study provides a genome-wide portrait of introgression between distantly related butterfly species. …”
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    Genome-wide introgression among distantly related Heliconius butterfly species
  14. 1414
    “…CONCLUSIONS: This study provides the first comprehensive portrait of global changes in the RNA splicing signatures that occur in hepatocellular carcinoma. …”
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    Global profiling of alternative RNA splicing events provides insights into molecular differences between various types of hepatocellular carcinoma
  15. 1415
    “…Not only did analyses of our AL data set validate the program by yielding a portrait of hominoid evolution in agreement with previous studies, but the accuracy and precision of our estimated ancestral effective population sizes and speciation times represent improvements. …”
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    In silico phylogenomics using complete genomes: a case study on the evolution of hominoids
  16. 1416
    “…Our data render the most comprehensive genetic portrait yet of this uncommon but lethal disease and may inform future classification schemes.…”
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    Online Artículo Texto
    Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2
  17. 1417
    “…Collectively, our findings provide a comprehensive portrait of the unique transcriptional signature and AS profile of CD4(+) T cells in human decidua and help us gain more understanding of the functional characteristic of these cells during early pregnancy.…”
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    Distinct Transcriptional and Alternative Splicing Signatures of Decidual CD4(+) T Cells in Early Human Pregnancy
  18. 1418
    “…The present study provided a list of tissue- and organ-specific genes that may be most suited for the following individual tissues/organs: Adipose tissue, bone marrow, brain, heart, kidney, liver, lung, ovary, skeletal muscle and testis; and also provides in these cases a representative, quantitative portrait of the relative, typical gene-expression profile in the form of searchable database tables.…”
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    Systematic identification of human housekeeping genes possibly useful as references in gene expression studies
  19. 1419
    “…Here, we investigate the transcriptomic alterations and splicing events during mouse lens formation using RNA-seq data from multiple developmental stages, and construct a molecular portrait of known and novel transcripts. We show that the extent of novelty of expressed transcripts decreases significantly in post-natal lens compared to embryonic stages. …”
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    Transcriptome analysis of developing lens reveals abundance of novel transcripts and extensive splicing alterations
  20. 1420
    “…CONCLUSIONS: Our study provides a quantitative global reference portrait of gene expression in the normal human thyroid and highlights differential expression between normal human thyroid and a pool of non-thyroid tissues useful for modeling correlations between thyroidal gene expression and specific thyroid functions and diseases. …”
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    A molecular view of the normal human thyroid structure and function reconstructed from its reference transcriptome map
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