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  1. 1581
    “…Although breast cancer (BC) has been historically considered a “cold tumor”, exciting progress in the genomic field leading to the characterization of the molecular portrait and the immune profile of TNBC has opened the door to novel therapeutic strategies, including Immune Checkpoint Inhibitors (ICIs), Poly ADP-Ribose Polymerase (PARP) inhibitors and Antibody Drug Conjugates (ADCs). …”
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    Immune-Based Therapy in Triple-Negative Breast Cancer: From Molecular Biology to Clinical Practice
  2. 1582
    “…Therefore, with the goal of developing a portrait of context-specific patterns to better elucidate how they govern distinct biological processes, this work presents a large-scale exploration of transcriptomic signatures across three different contexts (i.e., tissues, cell types, and cell lines) by leveraging over 600 gene expression datasets categorized into 98 subcontexts. …”
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    Elucidating gene expression patterns across multiple biological contexts through a large-scale investigation of transcriptomic datasets
  3. 1583
    “…Discrete relative phase (DRP) was used to assess coordination and variability between joints within a single limb and compared across limbs. Phase portraits were calculated by joint, and their areas were computed with a MATLAB script. …”
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    Comparison of Treadmill Gait Between a Pediatric-Aged Individual With SYNGAP1-Related Intellectual Disability and a Fraternal Twin
  4. 1584
    “…Flexural eczema and head and neck eczema were the most frequent clinical phenotypes, followed by hand eczema and portrait‐like dermatitis. Coexistence of more than 1 phenotype was documented in 126/139 (88.5%) adolescents. …”
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    Moderate‐to‐severe atopic dermatitis in adolescents treated with dupilumab: A multicentre Italian real‐world experience
  5. 1585
    “…CONCLUSIONS: This comprehensive portrait of rural–urban differences in dementia care highlights possible geographically based inequities and can be used by researchers and decision makers to guide development of more equitable dementia care policies. …”
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    Rural and urban differences in quality of dementia care of persons with dementia and caregivers across all domains: a systematic review
  6. 1586
    “…This study aimed to draw a portrait of polypharmacy among older adults with schizophrenia from 2000 to 2016. …”
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    Psychiatric and non-psychiatric polypharmacy among older adults with schizophrenia: Trends from a population-based study between 2000 and 2016
  7. 1587
    por Lesmann, Hellen, Lyon, Gholson J., Caro, Pilar, Abdelrazek, Ibrahim M., Moosa, Shahida, Pantel, Jean Tori, Hagen, Merle ten, Rosnev, Stanislav, Kamphans, Tom, Meiswinkel, Wolfgang, Li, Jing-Mei, Klinkhammer, Hannah, Hustinx, Alexander, Javanmardi, Behnam, Knaus, Alexej, Uwineza, Annette, Knopp, Cordula, Marchi, Elaine, Elbracht, Miriam, Mattern, Larissa, Jamra, Rami Abou, Velmans, Clara, Strehlow, Vincent, Nabil, Amira, Graziano, Claudio, Artem, Borovikov, Schnabel, Franziska, Heuft, Lara, Herrmann, Vera, Höller, Matthias, Alaaeldin, Khoshoua, Jezela-Stanek, Aleksandra, Mohamed, Amal, Lasa-Aranzasti, Amaia, Elmakkawy, Gehad, Safwat, Sylvia, Ebstein, Frédéric, Küry, Sébastien, Arlt, Annabelle, Marbach, Felix, Netzer, Christian, Kaptain, Sophia, Weiland, Hannah, Devriendt, Koen, Gripp, Karen W., Mücke, Martin, Verloes, Alain, Schaaf, Christian P., Nellåker, Christoffer, Solomon, Benjamin D., Waikel, Rebekah, Abdalla, Ebtesam, Nöthen, Markus M., Krawitz, Peter M., Hsieh, Tzung-Chien
    Publicado 2023
    “…An entry in GMDB consists of a medical image such as a portrait, X-ray, or fundoscopy, and machine-readable meta information such as a clinical feature encoded in HPO terminology or a disease-causing mutation reported in HGVS format. …”
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    GestaltMatcher Database - a FAIR database for medical imaging data of rare disorders
  8. 1588
    “…After divided the patients into two groups according to risk score, we identified differences in lipid-related metabolic processes and a detailed portrait of the immune landscapes of high- and low-risk groups. …”
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    A risk score model based on lipid metabolism-related genes could predict response to immunotherapy and prognosis of lung adenocarcinoma: a multi-dataset study and cytological validation
  9. 1589
    “…However, a genome-wide portrait on the contributing molecular factors to invasion heterogeneity is lacking. …”
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    Genome-wide analysis of three-way interplay among gene expression, cancer cell invasion and anti-cancer compound sensitivity
  10. 1590
    “…Despite the different histopathological portrait, AL and OA patients exhibited similar transcriptional levels of genes encoding key proteins in local immune response. …”
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    Immune response and innervation signatures in aseptic hip implant loosening
  11. 1591
    “…CONCLUSIONS: Our study advances the ABPP methodology to tissue sections, enabling high-resolution confocal fluorescence imaging of global SH activity in anatomically preserved complex native cellular environment. To achieve global portrait of SH activity throughout the section, a probe with broad reactivity towards the SH family members was employed. …”
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    High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections – Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils
  12. 1592
    “…The general practice professionals had generally sought to comply with the standards and to give an authentic portrait of the clinic. The few cases of misrepresention concerned standards that the professionals found too excessive. …”
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    The survey visit as a key evaluative event in accreditation–a qualitative study of survey visit experiences among surveyors and general practice professionals
  13. 1593
    “…Our data also identified the long noncoding RNA (lncRNA) transcriptional portrait associated with DNMT inhibition and identified 25 commonly upregulated and 60 commonly downregulated lncRNAs in response to Decitabine and 5-Azacytidinec treatment in both TNBC models. …”
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    Transcriptional alterations of protein coding and noncoding RNAs in triple negative breast cancer in response to DNA methyltransferases inhibition
  14. 1594
    “…OBJECTIVE: To draw a portrait of e-services as a digital approach to support digital health literacy in vulnerable populations amid the COVID-19 infodemic, and identify the barriers and facilitators for their implementation. …”
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    COVID-19 infodemic and digital health literacy in vulnerable populations: A scoping review
  15. 1595
    “…CONCLUSION: The real-time insights into the interrelated dynamics of public perceptions, responses, and media coverage provide an integrated portrait of the social developments during this outbreak. …”
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    Dynamics in public perceptions and media coverage during an ongoing outbreak of meningococcal W disease in the Netherlands
  16. 1596
    “…RESULTS: We provide a comprehensive portrait of the venom of R. metallica and show that the colony-wide venom consists of an exceptionally high diversity of functionally distinct toxins for an ant. …”
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    Intra-colony venom diversity contributes to maintaining eusociality in a cooperatively breeding ant
  17. 1597
    “…CONCLUSIONS: Although a comprehensive portrait of the relationship between audio features and stress recovery still warrants further research, the present study provides a starting point for future enquiries into the nuanced effects of musical audio features on stress recovery. …”
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    The sound of stress recovery: an exploratory study of self-selected music listening after stress
  18. 1598
    “…To accommodate our target population, we also incorporated recommendations from the Americans with Disabilities Act for website design, such as large text size, large paragraph spacing, highly contrasting text and background colors, use of headings and labels to describe the purpose of the content, portrait orientation without the need for horizontal scrolling, multiple ways to access a web page within a set of pages, ability to navigate web pages in sequential order, and in-text links that are descriptive. …”
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    Cancer Resource and Information Support (CRIS) for Bladder Cancer Survivors and Their Caregivers: Development and Usability Testing Study
  19. 1599
    “…Metabolomics revealed that the genomic portrait of HLE cells co-exist with profound reliance on glutamine to fuel tricarboxylic acid cycle, whereas HUH7 cells use both glucose and glutamine. …”
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    Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours
  20. 1600
    por Hsieh, Tzung-Chien, Mensah, Martin A., Pantel, Jean T., Aguilar, Dione, Bar, Omri, Bayat, Allan, Becerra-Solano, Luis, Bentzen, Heidi B., Biskup, Saskia, Borisov, Oleg, Braaten, Oivind, Ciaccio, Claudia, Coutelier, Marie, Cremer, Kirsten, Danyel, Magdalena, Daschkey, Svenja, Eden, Hilda David, Devriendt, Koenraad, Wilson, Sandra, Douzgou, Sofia, Đukić, Dejan, Ehmke, Nadja, Fauth, Christine, Fischer-Zirnsak, Björn, Fleischer, Nicole, Gabriel, Heinz, Graul-Neumann, Luitgard, Gripp, Karen W., Gurovich, Yaron, Gusina, Asya, Haddad, Nechama, Hajjir, Nurulhuda, Hanani, Yair, Hertzberg, Jakob, Hoertnagel, Konstanze, Howell, Janelle, Ivanovski, Ivan, Kaindl, Angela, Kamphans, Tom, Kamphausen, Susanne, Karimov, Catherine, Kathom, Hadil, Keryan, Anna, Knaus, Alexej, Köhler, Sebastian, Kornak, Uwe, Lavrov, Alexander, Leitheiser, Maximilian, Lyon, Gholson J., Mangold, Elisabeth, Reina, Purificación Marín, Carrascal, Antonio Martinez, Mitter, Diana, Herrador, Laura Morlan, Nadav, Guy, Nöthen, Markus, Orrico, Alfredo, Ott, Claus-Eric, Park, Kristen, Peterlin, Borut, Pölsler, Laura, Raas-Rothschild, Annick, Randolph, Linda, Revencu, Nicole, Fagerberg, Christina Ringmann, Robinson, Peter Nick, Rosnev, Stanislav, Rudnik, Sabine, Rudolf, Gorazd, Schatz, Ulrich, Schossig, Anna, Schubach, Max, Shanoon, Or, Sheridan, Eamonn, Smirin-Yosef, Pola, Spielmann, Malte, Suk, Eun-Kyung, Sznajer, Yves, Thiel, Christian T., Thiel, Gundula, Verloes, Alain, Vrecar, Irena, Wahl, Dagmar, Weber, Ingrid, Winter, Korina, Wiśniewska, Marzena, Wollnik, Bernd, Yeung, Ming W., Zhao, Max, Zhu, Na, Zschocke, Johannes, Mundlos, Stefan, Horn, Denise, Krawitz, Peter M.
    Publicado 2019
    “…METHODS: Here, we introduce an approach driven by artificial intelligence that uses portrait photographs for the interpretation of clinical exome data. …”
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    PEDIA: prioritization of exome data by image analysis
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