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341Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsiapor Garrido-Gomez, Tamara, Castillo-Marco, Nerea, Clemente-Ciscar, Mónica, Cordero, Teresa, Muñoz-Blat, Irene, Amadoz, Alicia, Jimenez-Almazan, Jorge, Monfort-Ortiz, Rogelio, Climent, Reyes, Perales-Marin, Alfredo, Simon, Carlos“…IMB was supported by the PhD program PRE2019-090770 and funding was provided by the grant RTI2018-094946-B-100 (MCIU/AEI/FEDER, UE) from the Spanish Ministry of Science and Innovation with CS as principal investigator. This research was funded partially by Igenomix S.L.…”
Publicado 2021
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342por Alhindi, Turki, Awad, Hamza, Alfaraj, Dunya, Elabdein Salih, Salih, Abdelmoaty, Maged, Muammar, Aroub“…The data collection was conducted by emergency medicine physicians who were given a detailed explanation of the purpose of the study and had training and supervision by the principal investigator. Results The study involved 214 patients who presented to the ED and had positive results on the SARS-CoV-2 reverse transcription polymerase chain reaction (RT-PCR) test and had troponin-I levels measured. …”
Publicado 2022
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343por Beogo, Idrissa, Sia, Drissa, Tchouaket Nguemeleu, Eric, Zhao, Junqiang, Gagnon, Marie-Pierre, Etowa, Josephine“…Using a 2-person approach, the principal investigator and one author will blindly screen eligible articles, extract data, and assess risk of bias. …”
Publicado 2022
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344“…Clinical examination was carried out by single trained calibrated principal investigator and data was recorded on self-structured recording format. …”
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345por Sprow, Grant, Afarideh, Mohsen, Dan, Joshua, Feng, Rui, Keyes, Emily, Grinnell, Madison, Concha, Josef, Werth, Victoria P.“…METHODS: We performed a chart review of all patients seen in the autoimmune skin disease clinic of the principal investigator during the study period. All patients included for analysis were systematically and prospectively asked about COVID-19 vaccination status, manufacturers, vaccine dates, autoimmune symptoms after the vaccine, and timing of symptom onset using a standardized template as part of their visit. …”
Publicado 2022
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346“…Utilizing the Nutrition Environment Measurement Scale for Vending Machines (NEMS-V), all VM within the campus were scored by the principal investigator pre-closure and 15% of VM on campus were randomly selected for evaluation when the university reopened fully to students. …”
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347por de Laurido, Lourdes E. Soto, Frontera, Walter, Ramos, Carlamarie Noboa, Huertas, Aracelis“…The 45.5% were affiliated to an academic institution or healthcare entrepreneur RESULTS/ANTICIPATED RESULTS: Awardees top career goals were: combine research & teaching-faculty (36.4%), clinical practice (36.4%) and Principal Investigator (PI) in a research institution (36.4%). …”
Publicado 2022
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348“…The contents of the instructions were recorded, and confirmed in monthly meetings with the principal investigator. The primary endpoint was the Hemoglobin A1c(HbA1c) level, and the secondary endpoints were high-density lipoprotein-cholesterol (HDL-c), low-density lipoprotein-cholesterol (LDL-c), Triglyceride (TG), degree of dietary self-management, degree of unbalanced diet and satisfaction with pharmacy services. …”
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349por Di Stefano, Leon, Ogburn, Elizabeth L., Ram, Malathi, Scharfstein, Daniel O., Li, Tianjing, Khanal, Preeti, Baksh, Sheriza N., McBee, Nichol, Gruber, Joshua, Gildea, Marianne R., Clark, Megan R., Goldenberg, Neil A., Bennani, Yussef, Brown, Samuel M., Buckel, Whitney R., Clement, Meredith E., Mulligan, Mark J., O’Halloran, Jane A., Rauseo, Adriana M., Self, Wesley H., Semler, Matthew W., Seto, Todd, Stout, Jason E., Ulrich, Robert J., Victory, Jennifer, Bierer, Barbara E., Hanley, Daniel F., Freilich, Daniel“…Harmonized de-identified data were collected via a common template spreadsheet sent to each principal investigator. The data were analyzed by fitting a prespecified Bayesian ordinal regression model and standardizing the resulting predictions. …”
Publicado 2022
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350por Heck, Johannes, Rath, Ann-Kathrin, Wons, Katrin, Schumacher, Carsten, Kutschenko, Anna, Noltemeyer, Nina, Ulaganathan, Sarana, Voßiek, Luca J., Hijma, Hemme, van Smeden, Jeroen, Schröder, Christoph, Stichtenoth, Dirk O., Wedemeyer, Heiner, Schindler, Christoph, Bosch, Jacobus J.“…RESULTS: Following a brief description of the different roles in clinical trials (e.g., sponsor, (principal) investigator, monitor) and an introduction into the principles of GCP, the documentation of adverse events, concomitant medication, medical history, and quality control are comprehensively discussed. …”
Publicado 2022
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351por Sharma, Dushyant Kumar, Bharti, Gaurav, Pegu, Julie, Bhumbla, Shayana, Paul, Lagan, Agarwal, Manisha, Shah, Gaurav, Mathur, Umang“…Details of the postoperative period and best-corrected visual acuity (BCVA) were collected from patient records by the principal investigator on day 1, 1 week, 4 weeks, 6 weeks, and 3 months post cataract surgery. …”
Publicado 2022
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352por Fleming, Stephen“…</span></p> <p class="p1"><span style="color:null"><span><strong>Short bio of the speaker:</strong> </span></span></p> <p class="p1">Steve is <span><span>Professor of Cognitive Neuroscience and Sir Henry Dale Fellow</span></span> at the Department of Experimental Psychology, Principal Investigator at the Wellcome Centre for Human Neuroimaging, and Group Leader at the Max Planck-UCL Centre for Computational Psychiatry and Ageing Research. …”
Publicado 2022
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353“…Finally, at the last visit the scar appearance was assessed by the Principal Investigator (PI) using the Mecott Modified Scar Scale (MMSS). …”
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354“…A total of eight study sites across five municipal planning regions of eThekwini District were visited. The principal investigator administered the validated structured standardised questionnaire, using participants’ language of choice, which was either English or isiZulu. …”
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355por Van Regemorter, Victoria, Coulie, Richard, Dollase, Jordi, Momeni, Mona, Stouffs, Alexandre, Quenon, Lisa, Mouraux, André, Huart, Caroline“…TRIAL REGISTRATION: This study was retrospectively registered on https://clinicaltrials.gov/ under the NCT04700891 number (principal investigator: Victoria Van Regemorter), in December 2020.…”
Publicado 2023
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356por Almahdi, Hatim Mohammed, Alabdrabulridha, Zuhair, AlAbbas, Jawad, Saad, Ali Albin, Alarka, Ismail, Alghatm, Sajjad, Alqasem, Hadi“…The inclusion criteria were adults aged ≥ 18 years. The principal investigator performed all the necessary measures for calibration in the forms of training on clinical examination and interviews. …”
Publicado 2022
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357por Asiago, Josephat, Albizem, Moetaz, Tieu, Holly L, Stecco, Kathryn, Moullan, Norman, Fenwick, Craig, Lin, Kai, Poffenbarger, Lauren, Lengsfeld, Thomas, Liu, David W, Hock, Björn M, Venkayya, Rajeev, Bhuyan, Prakash“…Only 1.3% (2/154) AEs (IRSRs, erythema and tenderness) were rated as possibly related to the investigational products by the principal investigator. CONCLUSION: Based upon preliminary data, AER001 and AER002 show adequate safety with no SAEs or ADAs. …”
Publicado 2023
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358“…Based on reasoned opinions issued by the respective ethics committee in charge of the coordinating principal investigator (coordinating ethics committee), the type and frequency of formal and content-related objections to applications according to § 7 of the German Good Clinical Practice (GCP) Regulation were systematically documented, and qualitative and quantitative analyses performed. 21 out of 44 members of the VFA participated in the survey. 288 applications for Phase I–IV studies submitted between January and December 2007 to 40 ethics committees were evaluated. …”
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359“…METHODS: 50 subjects (25 male, 25 female) were recruited from the principal investigator’s existing patient population at his pediatric primary care office. …”
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360por Buckley, Jack C., Brown, Adam P., Shin, John S., Rogers, Kirsten M., Hoftman, Nir N.“…A force transducer was used to apply linear force, increasing to 15 N or until the principal investigator deemed that the force be aborted for safety reasons. …”
Publicado 2016
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