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  1. 386761
    “…In summary, with recent progresses in biological and biotechnological areas, especially rapid development of advanced technologies in biological system modeling, functional genomics, computer-based analyzing tools, genetic engineering and molecular breeding, biological control and biotechnological applications in agriculture have brought about an extraordinary revolution and have been considered the most powerful approaches in maintaining or even increasing crop yield. …”
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    Enhancement of Plant Productivity in the Post-Genomics Era
  2. 386762
    “…Precipitating circumstances for legal intervention deaths most frequently were an alleged criminal activity in progress, the victim reportedly using a weapon in the incident, a mental health or substance abuse problem (other than alcohol abuse), an argument or conflict, or a recent crisis (during the previous or upcoming 2 weeks). …”
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    Surveillance for Violent Deaths — National Violent Death Reporting System, 27 States, 2015
  3. 386763
    por Khalid, Salema, Smith, Richard, Cole, Zoe
    Publicado 2019
    “…KEY LEARNING POINTS: The optimal strategies for monitoring disease progress in GCA remain uncertain, and currently rely on assessing clinical features and measuring inflammatory markers.  …”
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    20. Tocilizumab: is out of sight really out of mind?
  4. 386764
    por Mason, Alice, Williams, Emma
    Publicado 2019
    “…CASE DESCRIPTION: A 54-year-old previously fit and well man presented to the Emergency Department with a three-month history of progressively worsening shortness of breath and dry cough. …”
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    27. A new presentation of interstitial lung disease
  5. 386765
    “…Both conditions can present with polyarthralgia, but the chronic arthritis of AOSD can progress to destructive arthropathy.  The rashes in both conditions generally differ, helping to distinguish between the two. …”
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    20. A challenging diagnosis of adult-onset Still’s disease in the setting of raised anti-streptolysin O titres
  6. 386766
    por Alsaeid, Mohammed Awad
    Publicado 2019
    “…Although the exact etiology remains unclear, high-pressure-related intracarpal tunnel compression of the median nerve (MN), progressing ischemia, and mechanical strangulation are common mechanisms. …”
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    Dexamethasone versus Hyaluronidase as an Adjuvant to Local Anesthetics in the Ultrasound-guided Hydrodissection of the Median Nerve for the Treatment of Carpal Tunnel Syndrome Patients
  7. 386767
    “…The significantly increased mean expression for FNDC1, FN1, AR, and c-MYC in prostate tumor tissues in comparison with normal prostate tissues indicate that their overexpression is associated with increased risk of cancer progression in MoAA. DISCUSSION/SIGNIFICANCE OF IMPACT: These results show that the underexpression of miR-1207-3p and the overexpression of FNDC1, FN1, AR and MYC is associated with aggressive PCa in MoAA. miR-1207-3p, and it molecular target FNDC1, may be useful biomarkers for prognostication of PCa in MoAA.…”
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    2302: Downregulation of miR-1207-3p is correlated to upregulation of FNDC1, FN1, AR, and c-MYC in aggressive prostate cancer in men of African ancestry
  8. 386768
    “…This is consist with the proposed deleterious role for macrophages in tumor progression. Next, using nearest neighbor analysis we examined the effect of HLA-DR and Ki67 expression on spatial distribution of CD3+CD8+ T cells. …”
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    2367: Defining critical features of the immune microenvironment in melanoma using multiplex immunohistochemistry and spatial analysis
  9. 386769
    “…OBJECTIVE: To examine among youth (aged 12-17 years), young adults (aged 18-24 years), and adults (aged ≥25 years) the prevalence of first use of flavored tobacco products among new tobacco users and the association between first flavored use of a given tobacco product and tobacco use 1 year later, including progression of tobacco use. DESIGN, SETTING, AND PARTICIPANTS: This cohort study represents a longitudinal analysis of data from the Population Assessment of Tobacco and Health (PATH) Study, a nationally representative study with data collected in 2013 to 2014 (wave 1) and 2014 to 2015 (wave 2). …”
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    Association of Flavored Tobacco Use With Tobacco Initiation and Subsequent Use Among US Youth and Adults, 2013-2015
  10. 386770
    “…But may include; time to clinical improvement of at least 2 points on the WHO 9-point category ordinal scale [measured up to 29 days from randomisation], progression of disease (oxygen saturation (SaO(2)) <92%) or hospitalization or death, or change in time-weighted viral load [measured up to 29 days from randomisation]. …”
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    AGILE-ACCORD: A Randomized, Multicentre, Seamless, Adaptive Phase I/II Platform Study to Determine the Optimal Dose, Safety and Efficacy of Multiple Candidate Agents for the Treatment of COVID-19: A structured summary of a study protocol for a randomised platform trial
  11. 386771
    “…The COVIDornase trial intends to define the impact of aerosolized intra-tracheal dornase alfa administration on the severity and progression of acute respiratory distress syndrome (ARDS) in COVID-19 patients. …”
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    Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial
  12. 386772
    “…OBJECTIVES: To determine if a specific immunomodulatory intervention reduces progression of COVID-19-related disease to organ failure or death, compared to standard of care (SoC). …”
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    Repurposed immunomodulatory drugs for Covid-19 in pre-ICu patients - mulTi-Arm Therapeutic study in pre-ICu patients admitted with Covid-19 – Repurposed Drugs (TACTIC-R): A structured summary of a study protocol for a randomised controlled trial
  13. 386773
    “…Recently there has been concern regarding progression of a facial lesion on reducing to 5 mg of Prednisolone, and a further prednisolone course and optimised MMF were initiated. …”
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    O22 An inflammatory journey from brain to skin: a case of En Coupe De Sabre scleroderma presenting with raised intracranial pressure, seizures, and uveitis
  14. 386774
    por Davies, Justine I., Reddiar, Sumithra Krishnamurthy, Hirschhorn, Lisa R., Ebert, Cara, Marcus, Maja-Emilia, Seiglie, Jacqueline A., Zhumadilov, Zhaxybay, Supiyev, Adil, Sturua, Lela, Silver, Bahendeka K., Sibai, Abla M., Quesnel-Crooks, Sarah, Norov, Bolormaa, Mwangi, Joseph K., Omar, Omar Mwalim, Wong-McClure, Roy, Mayige, Mary T., Martins, Joao S., Lunet, Nuno, Labadarios, Demetre, Karki, Khem B., Kagaruki, Gibson B., Jorgensen, Jutta M. A., Hwalla, Nahla C., Houinato, Dismand, Houehanou, Corine, Guwatudde, David, Gurung, Mongal S., Bovet, Pascal, Bicaba, Brice W., Aryal, Krishna K., Msaidié, Mohamed, Andall-Brereton, Glennis, Brian, Garry, Stokes, Andrew, Vollmer, Sebastian, Bärnighausen, Till, Atun, Rifat, Geldsetzer, Pascal, Manne-Goehler, Jennifer, Jaacks, Lindsay M.
    Publicado 2020
    “…METHODS AND FINDINGS: We did a secondary analysis of cross-sectional, nationally representative, individual-patient data from 187,552 people with hypertension (mean age 48.1 years, 53.5% female) living in 43 low- and middle-income countries (LMICs) and 40,795 people with diabetes (mean age 52.2 years, 57.7% female) living in 28 LMICs on progress through cascades of care (condition diagnosed, treated, or controlled) for diabetes or hypertension, to indicate outcomes of provision of quality clinical care. …”
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    Association between country preparedness indicators and quality clinical care for cardiovascular disease risk factors in 44 lower- and middle-income countries: A multicountry analysis of survey data
  15. 386775
    “…Part 2 of the special issue on microsaccades is already in progress with articles currently under review and will be published in 2021.…”
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    Microsaccades: Empirical Research and Methodological Advances - Introduction to Part 1 of the Thematic Special Issue
  16. 386776
    “…Multiple efforts are ongoing to control COVID19 pandemic, and clinical practice is being adapted at the same time as the pandemic progresses around the world. To reduce unnecessary in-person appointments has become crucial to minimize hospital exposition. …”
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    Prospective Pilot Study of Telehealth As Domiciliary Follow-up after Hematopoietic Cell Transplantation during the COVID19 Pandemic
  17. 386777
    “…A fourth patient in the accelerated phase died 2 months after discharge, from disease progression and pulmonary infection. Conclusion: Although the sample size is still small to make conclusions regarding COVID-19 behavior in CML patients, the most severe cases occurred in patients not in MMR. …”
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    COVID-19 in Chronic Myeloid Leukemia Patients - Brazilian Experience
  18. 386778
    “…This novel virus can cause a rapid progression from cough to acute respiratory distress syndrome and death. …”
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    Outcomes of COVID-19 Infection in Patients with Hematologic Malignancies
  19. 386779
    “…In type 2 diabetes, risk of hyperglycemic crises decreased progressively with age (45-64 years IRR, 0.57 [95% CI, 0.51-0.63]; 65-74 years IRR, 0.44 [95% CI, .39-0.49]; ≥75 years IRR, 0.41 [95% CI, 0.36-0.47]). …”
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    Sociodemographic, Clinical, and Treatment-Related Factors Associated With Hyperglycemic Crises Among Adults With Type 1 or Type 2 Diabetes in the US From 2014 to 2020
  20. 386780
    “…In a population at high risk for progression to severe COVID-19, only 14% of our study population was vaccinated, whereas Missouri reported a 41% vaccination rate during this time.(6) These findings suggest that increased access alone may not improve vaccination rates in obstetrical patients even after counseling by expert clinicians. …”
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    Offering onsite COVID-19 vaccination to high-risk obstetrical patients: initial findings
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