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501“…The patient was treated with zoledronic acid, activated vitamin D, propranolol and radiotherapy to the thoracic vertebrae. …”
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502“…Thus, the improvement was correlated with the propranolol therapy. Here, we report a significant improvement of the postoperative complications of AGVI in a patient with SWS, following 4 months of oral propranolol course (1.5–2 mg/kg/day). …”
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503por Borowiecki, Paweł, Zdun, Beata, Popow, Natalia, Wiklińska, Magdalena, Reiter, Tamara, Kroutil, Wolfgang“…The enantiopure (R)-chlorohydrin (>99% ee) subsequently obtained was used for the synthesis of a series of model (R)-(+)-β-blockers (i.e., propranolol, alprenolol, pindolol, carazolol, moprolol, and metoprolol), which were produced with enantiomeric excess in the range of 96–99.9%. …”
Publicado 2022
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504por de Graaf, Chris, Oostenbrink, Chris, Keizers, Peter H. J., van Vugt-Lussenburg, Barbara M. A., Commandeur, Jan N. M., Vermeulen, Nico P. E.“…Detailed molecular dynamics (MD) simulations have been performed to reproduce and rationalize the experimental finding that the F483A mutant of CYP2D6 has lower affinity for R-propranolol than for S-propranolol. Wild-type (WT) CYP2D6 does not show this stereospecificity. …”
Publicado 2007
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505por Patel, Mayur B, McKenna, John W, Alvarez, JoAnn M, Sugiura, Ayaka, Jenkins, Judith M, Guillamondegui, Oscar D, Pandharipande, Pratik P“…Sympathetic hyperactivity after TBI manifests as catecholamine excess, hypertension, abnormal heart rate variability, and agitation, and is associated with poor neuropsychological outcome. Propranolol and clonidine are centrally acting drugs that may decrease sympathetic outflow, brain edema, and agitation. …”
Publicado 2012
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506“…Biomimetic membranes prepared with phospholipids and cholesterol of varying compositions were treated with β(1)-selective landiolol and esmolol and non-selective propranolol and alprenolol at 0.5–200 μM. The membrane interactivity and the antioxidant activity were determined by measuring fluorescence polarization and by peroxidizing membrane lipids with peroxynitrite, respectively. …”
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507por Wu, Hao, Song, Yue, Li, Junqin, Lei, Xing, Zhang, Shuaishuai, Gao, Yi, Cheng, Pengzhen, Liu, Bin, Miao, Sheng, Bi, Long, Yang, Liu, Pei, Guoxian“…In this study, we investigated the effect of systematic administration and local delivery of propranolol through composite scaffolds on bone healing. …”
Publicado 2019
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508por He, Huan, Li, Li, Zhao, Libo, Sun, Ning, Zhang, Meng, Cheng, Ying, Yu, Lu, Ma, Lin, Wang, Xiaoling“…Propranolol is now a preferred treatment for infantile hemangioma. …”
Publicado 2018
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509por Dai, Yuxin, Qiu, Mingke, Zhang, Shenglai, Peng, Jingyu, Hou, Xin, Liu, Jie, Li, Feifei, Ou, Jingmin“…SIMPLE SUMMARY: In this study, the researchers aimed to understand the mechanism behind the resistance of hemangioma stem cells (HemSCs) to propranolol, a commonly used drug for hemangioma treatment. …”
Publicado 2023
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510“…The effects of β2-adrenergic blocker propranolol (PRO) and μ-opioid receptor antagonist naltrexone (NTX) were tested using a preclinical model of human breast cancer. …”
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511por Filippi, Luca, Cavallaro, Giacomo, Berti, Elettra, Padrini, Letizia, Araimo, Gabriella, Regiroli, Giulia, Bozzetti, Valentina, De Angelis, Chiara, Tagliabue, Paolo, Tomasini, Barbara, Buonocore, Giuseppe, Agosti, Massimo, Bossi, Angela, Chirico, Gaetano, Aversa, Salvatore, Pasqualetti, Roberta, Fortunato, Pina, Osnaghi, Silvia, Cavallotti, Barbara, Vanni, Maurizio, Borsari, Giulia, Donati, Simone, Nascimbeni, Giuseppe, la Marca, Giancarlo, Forni, Giulia, Milani, Silvano, Cortinovis, Ivan, Bagnoli, Paola, Dal Monte, Massimo, Calvani, Anna Maria, Pugi, Alessandra, Villamor, Eduardo, Donzelli, Gianpaolo, Mosca, Fabio“…BACKGROUND: Retinopathy of prematurity (ROP) still represents one of the leading causes of visual impairment in childhood. Systemic propranolol has proven to be effective in reducing ROP progression in preterm newborns, although safety was not sufficiently guaranteed. …”
Publicado 2017
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512“…PURPOSE: Beta-adrenergic receptor (AR) antagonists, like propranolol, inhibit angiogenesis in multiple ocular conditions through an unknown mechanism. …”
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513“…Targeting of the vascular endothelium compartment explains, in part, the therapeutic efficacy of the nonselective β-adrenergic antagonist propranolol against common endothelial tumors such as hemangiomas. …”
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514por Smith, Emily C., Diedrich, André, Raj, Satish R., Gamboa, Alfredo, Shibao, Cyndya A., Black, Bonnie K., Peltier, Amanda, Paranjape, Sachin Y., Biaggioni, Italo, Okamoto, Luis E.“…In 16 patients we compared the combination of abdominal compression and propranolol with propranolol alone. The combination had no additional effect on standing HR (81±2 beats per minute for both interventions) but prevented the decrease in standing systolic blood pressure produced by propranolol (98±2 versus 93±2 mm Hg for propranolol; P=0.029), and significantly improved total symptom burden (−6±2 versus −1±2 for propranolol; P=0.041). …”
Publicado 2020
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515por Kaulanjan-Checkmodine, Priscilla, Oucherif, Sandra, Prey, Sorilla, Gontier, Etienne, Lacomme, Sabrina, Loot, Maya, Miljkovic-Licina, Marijana, Cario, Muriel, Léauté-Labrèze, Christine, Taieb, Alain, Moisan, François, Rezvani, Hamid Reza“…Since betablockers can antagonize the effect of natural ADRB agonists, we postulated that the catecholamine produced in situ in IH may have a role in the propranolol response. By quantifying catecholamines in the IH tissues, we found a higher amount of noradrenaline (NA) in untreated proliferative IHs than in involuted IHs or propranolol-treated IHs. …”
Publicado 2022
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516por Villain, Hélène, Benkahoul, Aïcha, Birmes, Philippe, Ferry, Barbara, Roullet, Pascal“…We have recently demonstrated that propranolol, a β-adrenergic antagonist, inhibited aversive memory reconsolidation in animals. …”
Publicado 2018
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517Exendin-4 Exacerbates Burn-Induced Morbidity in Mice by Activation of the Sympathetic Nervous Systempor Ji, Xiao-Jing, Hao, Ji-Wei, Li, Guang-Lei, Dong, Ning, Wang, Xin-Qi, Zhou, Min, Zhang, Qing-Hong, Yao, Yong-Ming“…RESULTS: Although the exacerbated burn-induced mortality by exendin-4 was worsened by propranolol pretreatment, the inhibition of T cell proliferation by exendin-4 in vitro could be restored by propranolol instead of exendin (9-39). …”
Publicado 2019
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518“…Fifth-year medical students comprised 50% of propranolol users. The prevalence of males using propranolol was lower compared to females. …”
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519por Lin, Shih-Yi, Wang, Ya-Yu, Chang, Cheng-Yi, Wu, Chih-Cheng, Chen, Wen-Ying, Kuan, Yu-Hsiang, Liao, Su-Lan, Chen, Chun-Jung“…Pretreatment with propranolol protected against postischemic brain infarction, edema, and apoptosis. …”
Publicado 2020
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520“…BACKGROUND/AIMS: The aim of this study was to compare the efficacy and tolerability of topiramate and propranolol in preventing pediatric cyclic vomiting syndrome. …”
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