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  1. 48441
    “…We included patients in one of two cohorts: 1) chronic proton pump inhibitor users (PPI), defined as use of any dose for 90 consecutive days, or 2) patients at hypoglycemia risk, defined by diabetes diagnosis; prescription for insulin or sulfonylurea; hemoglobin A1c < 7%; and age ≥ 65 years, renal insufficiency, or cognitive impairment. …”
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    Direct-to-consumer strategies to promote deprescribing in primary care: a pilot study
  2. 48442
    “…After adjusting for participant factors in the multivariable model (age, gender, BMI, diet, proton pump inhibitor use), OcMMP cohort was found to be associated with lower number of operational taxonomic units (OTUs) and Shannon Diversity Index when compared to healthy controls. …”
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    Gut Dysbiosis in Ocular Mucous Membrane Pemphigoid
  3. 48443
    “…BACKGROUND: For patients with gastro-oesophageal reflux symptoms, the preferred treatment is proton pump inhibitor (PPI) administration for approximately 8 weeks. …”
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    Protocol of a randomized, double-blind, placebo-controlled study of the effect of probiotics on the gut microbiome of patients with gastro-oesophageal reflux disease treated with rabeprazole
  4. 48444
    “…Re-irradiation techniques included; photons (n=26), protons (n=2) and stereotactic radiotherapy (n=6). …”
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    RONC-01. A 10 year, single institution experience of re-irradiation for paediatric intracranial tumours
  5. 48445
    “…Background: Stress ulcer prophylaxis (SUP) prescribed in patients admitted to surgical wards with a low risk of stress-related mucosal disease (SRMD) accounted for a considerable proportion of improper use of proton pump inhibitors (PPIs). This study aimed to analyze the appropriateness of SUP prescribing patterns and identify its associated factors in the orthopedics department of a tertiary hospital in the Northwestern China. …”
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    Appropriateness and Associated Factors of Stress Ulcer Prophylaxis for Surgical Inpatients of Orthopedics Department in a Tertiary Hospital: A Cross-Sectional Study
  6. 48446
    “…The presence of HCBS was assessed using an axial T2 fast spin-echo or FLAIR sequence. Proton MRS was recorded with voxel of interest focusing on cerebellar hemispheres and cerebellar vermis and avoiding cerebrospinal fluid spaces space using a single-voxel stimulated echo acquisition mode sequence. …”
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    Radiological hints for differentiation of cerebellar multiple system atrophy from spinocerebellar ataxia
  7. 48447
    “…Active EoE cases were further divided into proton pump inhibitor responsive (PPI‐r) and PPI‐nonresponsive (PPI‐nr) subgroups. …”
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    Esophageal epithelial immunoglobulin G is an important marker for the diagnosis and management of pediatric eosinophilic esophagitis
  8. 48448
    “…Mitochondrial-dependent ATP production and proton leak were reduced after treatment with metformin (p < 0.001). …”
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    Impact of Metformin Treatment on Human Placental Energy Production and Oxidative Stress
  9. 48449
    “…The most common PIMs were proton pump inhibitors and analgesic medication, with frequent PPOs being pneumococcal and influenza vaccinations, as well as osteoporosis prophylaxis. …”
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    Over- and under-prescribing, and their association with functional disability in older patients at risk of further decline in Germany – a cross-sectional survey conducted as part of a randomised comparative effectiveness trial
  10. 48450
    “…The primary endpoint will be the percentage reduction in hepatic fat content (%) measured using MRI-proton density fat fraction from baseline by at least 3.46% at week 16 after treatment initiation. …”
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    Efficacy and safety of guanabenz acetate treatment for non-alcoholic fatty liver disease: a study protocol for a randomised investigator-initiated phase IIa study
  11. 48451
    “…Then, brain damage was assessed using histology (Nissl and TUNEL staining) and biochemistry (proton magnetic resonance spectroscopy studies. Results: HI led to brain damage as assessed by histologic and biochemistry studies, associated with neuromotor impairment and increased seizures. …”
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    Role of 5HT1A Receptors in the Neuroprotective and Behavioral Effects of Cannabidiol in Hypoxic–Ischemic Newborn Piglets
  12. 48452
    “…This study quantified plasma lipid and particle sizes using high-throughput proton ((1)H) nuclear magnetic resonance (NMR) and tested their associations with obesity among breast cancer (BC) survivors. …”
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    Association of lipid profile with obesity among breast cancer survivors: a cross-sectional study
  13. 48453
    “…RESULTS: The results revealed that majority of the prescription were prescribed for females (73.5%) where proton-pump inhibitors (PPIs), analgesics, vitamins, and single antibiotics were most frequently prescribed medicine for the female patients compared to male patients. …”
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    A cross-sectional study on current prescription trends and errors in outpatient department of a Bangladeshi secondary care district hospital
  14. 48454
    “…It is further supported by the proton NMR, showing the disappearance of aldehyde peaks and the formation of a new imine peak. …”
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    An efficient 2-aminothiazolesalicylaldehyde fluorescent chemosensor for Fe(2+) ion detection and a potential inhibitor of NUDT5 signaling hormone for breast cancer cell and molecular keypad lock application
  15. 48455
    “…No statistically significant effects were detected for concomitant cytochrome P450 (CYP) 3A4 inhibitors or inducers, CYP2C8 or P-glycoprotein inhibitors, serum albumin, mild/moderate renal impairment, or mild hepatic impairment. Concomitant proton pump inhibitors had no clinically significant effect on lucitanib absorption. …”
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    Population Pharmacokinetic Modeling of Lucitanib in Patients with Advanced Cancer
  16. 48456
    “…The patient characteristics included the following: Age (in years), 69.9±11.3; male/female ratio, 146/210; body mass index, 23.0±3.8; reflux esophagitis (M/A/B/C), 143/19/3/3; atrophic gastritis (C-0/C1-3/O1-3), 132/100/124; proton pump inhibitor potassium competitive acid blocker/aspirin/ursodeoxycholic acid/gall bladder stones/cholecystectomy, 105/27/18/43/18; BLI bile score, 7.10 (±14.34); CSS score, 3.55 (±3.80); BSFS score, 3.91 (±1.02); and FSSG score, 4.80 (±5.76). …”
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    Association between bile area in the duodenal bulb and abdominal symptoms: Quantitative analysis using blue laser imaging
  17. 48457
    “…Histologic remission rate and therapies utilized [proton pump inhibitor (PPI), topical steroid, dietary elimination] were assessed. …”
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    Pediatric eosinophilic esophagitis outcomes vary with co-morbid eczema and pollen food syndrome
  18. 48458
    “…Patients with ICI-AKI were significantly more likely to be treated with fluindione [adjusted odds ratio (OR) 6.53, 95% confidence interval (95% CI) 2.21–19.31; P = 0.0007], a non-steroidal anti-inflammatory drug (NSAID, OR 3.18, 95% CI 1.07–9.4; P = 0.0368) or a proton-pump inhibitor (PPI, OR 2.18, 95% CI 1.42–3.34; P = 0.0004). …”
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    Risk factors associated with immune checkpoint inhibitor–induced acute kidney injury compared with other immune-related adverse events: a case–control study
  19. 48459
    “…Many researchers have been taking advantage of density functional theory (DFT), a computationally inexpensive yet reputable method for the prediction of carbon and proton NMR spectra of metabolites. However, such methods are expected to have some error in predicted (13)C and (1)H NMR spectra with respect to experimentally measured values. …”
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    An initial investigation of accuracy required for the identification of small molecules in complex samples using quantum chemical calculated NMR chemical shifts
  20. 48460
    “…Microbial signatures for COVID-19 were distinct from diabetes, inflammatory bowel disease, and proton-pump inhibitors but overlapping for rheumatoid arthritis. …”
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    Human Gut Microbiota and Its Metabolites Impact Immune Responses in COVID-19 and Its Complications
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