“…We conducted a network meta‐analysis to evaluate efficacy and safety of proton pump inhibitors (PPIs), histamine‐2‐receptor antagonists, potassium‐competitive acid blockers (PCABs), and alginates in patients with endoscopy‐negative reflux disease. …”
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“…We also observed transcriptional changes that support the occurring of an energetics imbalance, compensated by a reduced activity of the electron transport chain, decreased export of protons, and a remodeling of central metabolism. The most striking difference between the two strains was the induction in the sigE mutant of several stress-related genes, in particular, the genes encoding the ECF sigma factor SigH and the transcriptional regulator WhiB6. …”
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“…Six month old male WAG/RijCmcr rats were irradiated at a ground-based charged particle accelerator facility with high energy ion beams broadly representative of GCRs: protons, silicon and iron. Irradiation was given either as a single ion beam or as a combination of three ion beams. …”
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“…Later, a comprehensive quantitative evaluation was performed on an unseen dataset, which included calculating global image similarity metrics, segmentation-based measures and proton therapy-specific metrics. Main results. We found improved performance for our proposed method, compared to a baseline cycleGAN implementation, on image-similarity metrics such as Mean Absolute Error calculated for a matched virtual CT (55.0 ± 16.6 HU proposed versus 58.9 ± 16.8 HU baseline). …”
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“…Forty metabolites were detected in fermented and pasteurized coconut milk by proton nuclear magnetic resonance ((1)H NMR) metabolomics. …”
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“…BACKGROUND: Despite the widespread use of proton density fat fraction (PDFF) measurements with magnetic resonance imaging (MRI) to track disease progression in muscle disorders, it is still unclear how these findings relate to histopathological changes in muscle biopsies of patients with limb‐girdle muscular dystrophy autosomal recessive type 12 (LGMDR12). …”
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“…Fougerite is a 2D-layered mineral in which the hydrous interlayers themselves harbor 2D solutions, in effect constricted to ~ 1D by preferentially directed electron hopping/tunneling, and proton Gröthuss ‘bucket-brigading’ when subject to charge. …”
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“…These observations are consistent with a rate-limiting unimolecular step involving a proton transfer following adenine ring opening. We synthesized N(1)-(5-phospho-β-D-ribosyl)-ADP (PRADP), which could not be processed by HisIE. …”
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“…Omeprazole, a potent proton pump inhibitor drug, is widely used to treat this condition, with recommended withholding periods (RWPs) for racing varying from ‘not on race day’ to ‘2 clear days’. …”
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“…The quantitation of conversion of [M + H]+, which was the protonated precursor ion, to the corresponding product ions was performed using multiple reaction monitoring (MRM) with a mass-to-charge ratio (m/z) of 544 > 397.005 for DOX, 465.05 > 252.03 for SOR, and 394 > 278 for the IS. …”
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“…The DFT studies favored the 4-ethynyltoluene (HC≡CPhMe) coordination pathway over the p-toluenesulfonyl hydrazide (NH(2)NHSO(2)C(6)H(4)CH(3)) coordination pathway, and that proceeded by a crucial intermolecular hydrazide-assisted proton transfer step. The gold(I) complexes (1–4)b were synthesized from the {[(4-R(2)-2,6-t-Bu(2)-C(6)H(2)O)(N(R(1))(2))]CH}(+)OTf(–) (1–4)a by treatment with (Me(2)S)AuCl in the presence of NaH as a base. …”
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“…Results on regional pancreatic fat assessment are also presented, by intersecting the three‐dimensional parts segmentation with one available proton density fat fraction (PDFF) image. STATISTICAL TEST: Wilcoxon signed rank test and Mann–Whitney U‐test for comparisons. …”
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“…Perinatal clinical data were collected. T1, T2 and proton density (PD) values were measured in the white matter of the frontal lobe, parietal lobe, temporal lobe and occipital lobe, centrum semiovale, periventricular white matter, thalamus, lenticular nucleus, caudate nucleus, corpus callosum and cerebellum, which were generated by MAGiC. …”
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“…METHODS: 102 postmenopausal women were included, 56 of whom had a fragility fracture. Mean proton density fat fraction (PDFF) was measured in the psoas (PDFF(Psoas)) and paravertebral (PDFF(Paravertebral)) muscles at the lumbar level, as well as in the lumbar spine and non-dominant hip using chemical shift encoding-based water-fat imaging. …”
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“…All the subjects underwent proton magnetic resonance spectroscopy and feature tracking cardiac magnetic resonance imaging to measure myocardial strain. …”
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“…Hyperfractionated RT is not superior to conventional RT 9. Both photon and proton RT are effective. 10. CT increases survival, especially in high-risk patients. 11. …”
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“…The Maudsley Guidelines recommend that if SSRIs cannot be avoided in those assessed as high bleeding risk, then gastro-protective proton pump inhibitors (PPIs) should be prescribed. …”
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“…The most common discharge medications were anti-platelets (95%), beta-blockers (78.5%), statins (70.2%), and proton-pump inhibitors (PPI) (64.5%). The hospital stay days ranged from 1 to 20 days with a mean of 4.83 ± 3.38. …”
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“…Next, we describe our efforts to understand selectivity in a series of NHC-catalyzed kinetic resolutions, where we discovered that the electrostatic stabilization of key proton(s) is the common driver of selectivity. Finally, we discuss our breakthrough in understanding asymmetric silylium ion-catalyzed Diels–Alder cycloaddition of cinnamate esters to cyclopentadienes. …”
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“…However, since it contains exchangeable >N-H protons, its analysis via (1)H NMR spectroscopy, which is a widely employed technique in untargeted metabolomic studies, is rendered complicated. …”
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