“…All patients experienced anti-reflux treatment with proton pump inhibitors (PPIs) plus prokinetic agents for at least 2 weeks and were divided into responders and non-responders based on the treatment response. …”
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“…The bioactivities of C. caesia extracts were evaluated using in vitro tests; total phenolic content (TPC), antioxidant (DPPH and FRAP) and α-glucosidase inhibitory activity. Proton nuclear magnetic resonance ((1)H NMR)-based metabolomics approach was employed to differentiate the most active extracts based on their metabolite profiles and correlation with bioactivities. …”
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“…METHOD: We enrolled 84 glioma patients of different tumor grades in this retrospective study. Amide proton transfer CEST and structural Magnetic Resonance (MR) imaging at 7T were performed preoperatively, and the tumor regions are manually segmented, leading to the “annotation” maps that offers the location and shape information of the tumors. …”
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“…All subjects received a fat-saturated sagittal 2D proton density reference sequence without acceleration and four additional acquisitions with different acceleration levels: 2, 3, 4 and 6. …”
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“…In the presence of IL-1β, adenosine-treated cells induced higher ATP production, basal respiration and proton leak compared to IL-1β without adenosine. Surprisingly, adenosine had no additional effect on the IL-1β-induced higher glycolysis rate demonstrated by the extracellular acidification rate (ECAR). …”
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“…Hepatic steatosis was then classified according to magnetic resonance imaging proton density fat fraction (PDFF). Receiver operating curve (ROC) analysis was performed to evaluate the diagnostic performance in the diagnosis of steatosis. …”
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“…This work presents novel atmospheric in situ proton-transfer-reaction time-of-flight mass spectrometry (PTR-ToF-MS) measurements of VOCs at Toolik Field Station (TFS; 68°38′ N, 149°36’ W), in the Alaskan Arctic tundra during May–June 2019. …”
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“…METHODS: Urine specimens of young Nicaraguan participants 12–23 years without CKDnt (n=136) were analyzed by proton nuclear magnetic resonance spectroscopy for 50 metabolites associated with kidney dysfunction. …”
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“…Products formed during ketogenesis (HMG-CoA, acetoacetate, β-hydroxybutyrate) are created as negatively charged bases, not acids, and the final ketone body, acetone, does not have pH-dependent ionizable groups. Proton release or uptake during ketogenesis and ketolysis are predominantly caused by covalent modification, not acid dissociation/association. …”
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“…Additionally, strip-segmented ionization chamber arrays have shown potential for the experimental measurement of dose rate distribution in proton pencil beam scanning. Radiochromic films, such as Gafchromic(TM) EBT3, have been used for absolute dose measurement and to validate MC simulation results in high-energy X-rays, triggering the FLASH effect. …”
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“…We found two groups of acid‐sensitive DEG/ENaCs characterised by being either inhibited or activated by increasing proton concentrations. Three of these acid‐sensitive C. elegans DEG/ENaCs were activated by acidic pH, making them functionally similar to the vertebrate ASICs. …”
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“…To access group 3 alkyl complexes without the intermediacy of [(XII(2))M(CH(2)SiMe(3))(3)], the XII(2) ligand was protonated using [H(OEt(2))(2)][B(C(6)F(5))(4)] to form [H(XII(2))][B(C(6)F(5))(4)], and subsequent reaction with [M(CH(2)SiMe(3))(3)(THF)(2)] (M = Y, Sc) directly afforded the cationic scandium and yttrium dialkyl complexes [(XII(2))M(CH(2)SiMe(3))(2)][B(C(6)F(5))(4)] {M = Y (2) and Sc (3)}. …”
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“…In contrast, the expression of two pyruvate transporters (YhjX and YjiY) and genes involved in pyruvate metabolism, as well as genes involved in generating proton motive force (PMF), was antimicrobial specific. …”
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“…METHODS: Self-administered mailed surveys were sent to 1,000 members who experienced a step-therapy edit from September 1, 2002, through January 31, 2003, for proton pump inhibitors or nonsteroidal anti-inflammatory drugs. …”
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“…For drug induced anaphylaxis, parenteral route of drug administration and proton pump inhibitor (PPI) allergy were considered as risk factors for grade 5 anaphylaxis [p < 0.001, OR (CI) = 6.5 (2.5–17.0); p = 0.011, OR (CI) = 10.3 (1.6–63.3)]. …”
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“…Malonyl-CoA was successively reduced through protonation by the Tyr743–Arg746 pair in SDR3 and the catalytic triad (Thr165–Tyr178–Lys182) in SDR1 after nucleophilic attack from NADPH hydrides. …”
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“…OBJECTIVES: This study aimed to assess predictors of the response to varying durations of proton pump inhibitor (PPI) use and lifestyle modification treatment for laryngopharyngeal reflux disease (LPRD). …”
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“…BACKGROUND: This is an open-label, single-arm, single-center pilot study using 7-Tesla in vivo proton magnetic resonance spectroscopy ((1)H MRS) to measure brain cortical glutathione concentration at baseline before and during the use of oral fumarates as a disease-modifying therapy for multiple sclerosis. …”
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“…MRI was performed on both ankle joints of all subjects in the 1.5 T and 3.0 T MRI scanners using survey sequences, proton density sequences in the coronal and sagittal planes, and VIBE sequences. …”
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“…All participants underwent 3.0 Tesla MRI with coronal T1-weighted turbo spin echo (TSE), coronal proton density (PD)–weighted turbo spin echo (TSE), and T1-weighted three-dimensional (3D) volume interpolated breath-hold examination (VIBE) sequence. …”
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