“…It was found that the most probable free radicals scavenging mechanism in nonpolar phase is the hydrogen atom transfer from the amide group of compound 7, while in polar medium the process is expected to occur by a proton transfer. The current study outlines a perspective leading structure, bearing the potential for a new anti-PD drug. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To address this limitation of Ad, we have synthesized two variants of folic acid (FA)-conjugated methoxy poly(ethylene glycol)-b-poly{N-[N-(2-aminoethyl)-2-aminoethyl]-L-glutamate (P(5)N(2)LG-FA and P(5)N(5)LG-FA) using 5 kDa poly(ethylene glycol) (PEG) with a different level of protonation (N(2) < N(5) in terms of charge), along with a P(5)N(5)LG control polymer without FA. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…[Image: see text] The OH-initiated degradation of 2-amino-2-methyl-1-propanol [CH(3)C(NH(2))(CH(3))CH(2)OH, AMP] was investigated in a large atmospheric simulation chamber, employing time-resolved online high-resolution proton-transfer reaction-time-of-flight mass spectrometry (PTR-ToF-MS) and chemical analysis of aerosol online PTR-ToF-MS (CHARON-PTR-ToF-MS) instrumentation, and by theoretical calculations based on M06-2X/aug-cc-pVTZ quantum chemistry results and master equation modeling of the pivotal reaction steps. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…They also more often used sulfonylurea (p = 0.004), dipeptidyl peptidase-4 inhibitor (p < 0.001), thiazolidinediones (p < 0.001), glucagon-like peptide 1 [GLP-1] receptor agonists (p < 0.001), alpha-glucosidase inhibitor (p < 0.001), and H2 blocker/proton pump inhibitors [PPI] (p < 0.001) than the VitB12-normal group. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A total of 35 patients (74%) met clinical eligibility for LAI-CAB/RPV, including 4 patients who required a transition off proton pump inhibitor therapy to accommodate oral RPV. …”
Enlace del recurso
Enlace del recurso

“…The data achieved clearly demonstrated that compounds 2(I(2))(iPr) and 2(Cl(2))(iPr) were undergoing a series of transformation reactions in DMSO (with higher rates for the iodido complex 2(I(2))(iPr)), ultimately generating cyclometalated species through a mechanism involving DMSO as a coordinated proton abstractor. The cyclometalated complexes detected in solution were subsequently prepared; hence, pure [RuCl(p-cym)(κ(2)C-diisopropyl(1-pyrenyl)phosphane)] (3(Cl)(iPr)), [RuI(p-cym)(κ(2)C-diisopropyl(1-pyrenyl)phosphane)] (3(I)(iPr)), and [Ru(p-cym)(κS-dmso)(κ(2)C-diisopropyl(1-pyrenyl)phosphane)]PF(6) (3(dmso)(iPr)) were synthesized and fully characterized. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We calculated prevalence of adenomas and CRCs adjusted for sex, 5-year age group, family history of CRC, smoking, diabetes and use of aspirin, hormonal therapy and proton-pump inhibitors use. Thereafter we calculated estimated transition rate (eTR) with confidence intervals (CIs) defined as adjusted prevalence of more advanced lesion divided by adjusted prevalence of less advanced lesion. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Compared to those of NT, TFAM-KD-C had not only a lower mtDNA copy number (p = 0.050), but also lower oxygen consumption rates (OCR), including basal respiration (OCR(BR)), ATP-coupled respiration (OCR(ATP)), reserve capacity (OCR(RC)), and proton leak (OCR(PL))(all with p = 0.050). In contrast, TFAM-KD-C expressed a higher extracellular acidification rate (ECAR)/OCR(BR) ratio (p = 0.050) and a faster wound healing migration at 6, 12, and 18 h, respectively (all with p = 0.050). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We evaluated the effects of signal transducer and activator of transcription 6 (STAT6) signaling inhibition by RNA interference, a STAT6 inhibitor, AS1517499, as well as the proton pump inhibitor omeprazole. RESULTS: EoE patients showed decreased epithelial CD73(+)CD104(+) cell content. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In vivo preclinical imaging was performed with (133)La-PSMA-I&T on LNCaP tumor–bearing mice. Results: Proton irradiations for 100 µA·min at 23.3 MeV yielded 214 ± 7 MBq of (133)La and 28 ± 1 MBq of (135)La using (135)BaCO(3), 59 ± 2 MBq of (133)La and 35 ± 1 MBq of (135)La using (nat)BaCO(3), and 81 ± 3 MBq of (133)La and 48 ± 1 MBq of (135)La using (nat)Ba metal. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Fetal brain creatine and choline were quantified using proton magnetic resonance spectroscopy. Infant neurodevelopment at 18 months was measured using Bayley Scales of Infant and Toddler Development III and Infant-Toddler Social and Emotional Assessment. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The ground-state oxidation potentials were linearly correlated with the pK(a) of the N-heteroaromatic ligand [pK(a)(L)], the (1)H NMR chemical shift of the ortho proton on the coordinating ligand, and the Hammett constant (σ) of the pyridyl-ligand substituent. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…All patients were instructed not to use medications with known interactions, especially proton pump inhibitors and alcohol use. CONCLUSION: Lymphocutaneous sporotrichosis is the most common manifestation, but there is a need for care teams working in primary and secondary care to identify atypical skin lesions and expand the investigation into the possibility of fungal infections. …”
Enlace del recurso
Enlace del recurso

“…BACKGROUND: The efficacy and safety of high‐dose amoxicillin (AMX) and proton pump inhibitors (PPI) dual therapy raises much more attention in recent years. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Those with NTIS showed a reduced maximal respiratory capacity and a reduced proton leak, compared to those with normal FT3 serum values. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here we describe a case of IAS with use of Proton pump inhibitors, PPIs. CASE REPORT: 49year old man came with complaints of recurrent documented hypoglycemia for the past 3months. …”
Enlace del recurso
Enlace del recurso

“…Different pH conditions involved surface protonation and formation/disruption of intermolecular interactions, influencing both the release rate and the total released amount of naproxen. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It is designed to collide proton-proton (p-p) at a center-of-mass energy of sqrt(s) = 14 TeV, with a peak instantaneous luminosity of 1034 cm−2s−1. …”
Enlace del recurso

“…Les quarks et les gluons, qui sont les constituants des protons et des neutrons dans notre Univers refroidi, étaient alors trop chauds pour s’associer. …”
Enlace del recurso