The Quest for a Simple Bioactive Analog of Paclitaxel as a Potential Anticancer Agent

por Kingston, David G. I., Snyder, James P.
Publicado 2014

Urinary Concentrations of Phthalates in Couples Planning Pregnancy and Its Association with 8-Hydroxy-2′-deoxyguanosine, a Biomarker of Oxidative Stress: Longitudinal Investigation...

por Guo, Ying, Weck, Jennifer, Sundaram, Rajeswari, Goldstone, Alexandra E., Buck Louis, Germaine, Kannan, Kurunthachalam
Publicado 2014

High-Resolution Low-Field Molecular Magnetic Resonance Imaging of Hyperpolarized Liquids

por Coffey, Aaron M., Kovtunov, Kirill V., Barskiy, Danila A., Koptyug, Igor V., Shchepin, Roman V., Waddell, Kevin W., He, Ping, Groome, Kirsten A., Best, Quinn A., Shi, Fan, Goodson, Boyd M., Chekmenev, Eduard Y.
Publicado 2014

Explicit Polarization: A Quantum Mechanical Framework for Developing Next Generation Force Fields

por Gao, Jiali, Truhlar, Donald G., Wang, Yingjie, Mazack, Michael J. M., Löffler, Patrick, Provorse, Makenzie R., Rehak, Pavel
Publicado 2014

Phylogenomically Guided Identification of Industrially Relevant GH1 β-Glucosidases through DNA Synthesis and Nanostructure-Initiator Mass Spectrometry

por Heins, Richard A., Cheng, Xiaoliang, Nath, Sangeeta, Deng, Kai, Bowen, Benjamin P., Chivian, Dylan C., Datta, Supratim, Friedland, Gregory D., D’Haeseleer, Patrik, Wu, Dongying, Tran-Gyamfi, Mary, Scullin, Chessa S., Singh, Seema, Shi, Weibing, Hamilton, Matthew G., Bendall, Matthew L., Sczyrba, Alexander, Thompson, John, Feldman, Taya, Guenther, Joel M., Gladden, John M., Cheng, Jan-Fang, Adams, Paul D., Rubin, Edward M., Simmons, Blake A., Sale, Kenneth L., Northen, Trent R., Deutsch, Samuel
Publicado 2014

Modeling, Molecular Dynamics Simulation, and Mutation Validation for Structure of Cannabinoid Receptor 2 Based on Known Crystal Structures of GPCRs

por Feng, Zhiwei, Alqarni, Mohammed Hamed, Yang, Peng, Tong, Qin, Chowdhury, Ananda, Wang, Lirong, Xie, Xiang-Qun
Publicado 2014

Development and Characterization of a Novel Mouse Line Humanized for the Intestinal Peptide Transporter PEPT1

por Hu, Yongjun, Xie, Yehua, Wang, Yuqing, Chen, Xiaomei, Smith, David E.
Publicado 2014

Structure-Based Prediction of Drug Distribution Across the Headgroup and Core Strata of a Phospholipid Bilayer Using Surrogate Phases

por Natesan, Senthil, Lukacova, Viera, Peng, Ming, Subramaniam, Rajesh, Lynch, Sandra, Wang, Zhanbin, Tandlich, Roman, Balaz, Stefan
Publicado 2014

Effects of Toxicologically Relevant Xenobiotics and the Lipid-Derived Electrophile 4-Hydroxynonenal on Macrophage Cholesterol Efflux: Silencing Carboxylesterase 1 Has Paradoxical E...

por Ross, Matthew K., Borazjani, Abdolsamad, Mangum, Lee C., Wang, Ran, Crow, J. Allen
Publicado 2014

A Philosophy for CNS Radiotracer Design

por Van de Bittner, Genevieve C., Ricq, Emily L., Hooker, Jacob M.
Publicado 2014

Structure-Based Virtual Screening of the Nociceptin Receptor: Hybrid Docking and Shape-Based Approaches for Improved Hit Identification

por Daga, Pankaj R., Polgar, Willma E., Zaveri, Nurulain T.
Publicado 2014

A Conserved Acidic Residue in Phenylalanine Hydroxylase Contributes to Cofactor Affinity and Catalysis

por Ronau, Judith A., Paul, Lake N., Fuchs, Julian E., Liedl, Klaus R., Abu-Omar, Mahdi M., Das, Chittaranjan
Publicado 2014

[(18)F](2S,4S)-4-(3-Fluoropropyl)glutamine as a Tumor Imaging Agent

por Wu, Zehui, Zha, Zhihao, Li, Genxun, Lieberman, Brian P., Choi, Seok Rye, Ploessl, Karl, Kung, Hank F.
Publicado 2014

PET Imaging of Fatty Acid Amide Hydrolase with [(18)F]DOPP in Nonhuman Primates

por Rotstein, Benjamin H., Wey, Hsiao-Ying, Shoup, Timothy M., Wilson, Alan A., Liang, Steven H., Hooker, Jacob M., Vasdev, Neil
Publicado 2014

Involvement of GABA Transporters in Atropine-Treated Myopic Retina As Revealed by iTRAQ Quantitative Proteomics

por Barathi, Veluchamy A., Chaurasia, Shyam S., Poidinger, Michael, Koh, Siew Kwan, Tian, Dechao, Ho, Candice, Iuvone, P. Michael, Beuerman, Roger W., Zhou, Lei
Publicado 2014

One-Electron Oxidation of Gemcitabine and Analogs: Mechanism of Formation of C3′ and C2′ Sugar Radicals

por Adhikary, Amitava, Kumar, Anil, Rayala, Ramanjaneyulu, Hindi, Ragda M., Adhikary, Ananya, Wnuk, Stanislaw F., Sevilla, Michael D.
Publicado 2014

POSSIM: Parameterizing Complete Second-Order Polarizable Force Field for Proteins

por Li, Xinbi, Ponomarev, Sergei Y., Sigalovsky, Daniel L., Cvitkovic, John P., Kaminski, George A.
Publicado 2014

Unusually Efficient Pyridine Photodissociation from Ru(II) Complexes with Sterically Bulky Bidentate Ancillary Ligands

por Knoll, Jessica D., Albani, Bryan A., Durr, Christopher B., Turro, Claudia
Publicado 2014

The Specialized Hsp70 (HscA) Interdomain Linker Binds to Its Nucleotide-Binding Domain and Stimulates ATP Hydrolysis in Both cis and trans Configurations

por Alderson, T. Reid, Kim, Jin Hae, Cai, Kai, Frederick, Ronnie O., Tonelli, Marco, Markley, John L.
Publicado 2014

Comparing and Correlating Solubility Parameters Governing the Self-Assembly of Molecular Gels Using 1,3:2,4-Dibenzylidene Sorbitol as the Gelator

por Lan, Yaqi, Corradini, Maria G., Liu, Xia, May, Tim E., Borondics, Ferenc, Weiss, Richard G., Rogers, Michael A.
Publicado 2014