“…Preliminary screening of the compounds for antiviral, antibacterial, antifungal and antiproliferative properties in vitro revealed 1-oxa-2-azaspiro[4.7]dodec-2-en-3-amine and 3a,4,5,6,7,8,9,9a-octahydrocycloocta[d]isoxazol-3-amine with activity against the influenza A/Puerto Rico/8/34 (H1N1) virus in the submicromolar range, and high values of selectivity index. …”
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“…A 51-year-old Puerto Rican woman, with a known but inconclusive diagnosis of interstitial lung disease (ILD) since 2002 and recent moderate COVID-19, is now presenting with subacute worsening dyspnea on exertion. …”
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“…Meanwhile, the daily density of PPE litters in San Manuel, Puerto Princesa ranged from 0 to 9.9 × 10(−2) items m(−2), with a mean density of 8 × 10(−3) items m(−2). …”
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“…We investigated the cytotoxicity of R. stricta leaves extract and its antiviral activity against influenza virus (A/Puerto Rico/8/34 (H1N1)) using the MTT assay. The mode of action of the plant leaves extract during the viral life cycle was tested using time-of-addition assay. …”
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“…Variants in the HPS1 gene were found in approximately 15% of HPS patients, most of whom harbor the Puerto Rican founder mutation. In this study, we report six affected individuals from three nonconsanguineous families of Ashkenazi Jewish descent, who presented with OCA and multiple ecchymoses and had normal platelet number and size. …”
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“…Xylazine, an alpha-2 adrenergic receptor agonist typically used as a sedative and analgesic in veterinary medicine, is being illicitly supplied to persons who inject drugs (PWID), especially in Puerto Rico and Philadelphia, Pennsylvania in the USA. …”
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“…METHODS: This is a cross-sectional study conducted using Behavioral Risk Factor Surveillance System (BRFSS) secondary data collected in 2019 and covering 49 U.S. states, the District of Columbia, Guam, and the Commonwealth of Puerto Rico. A total of 15,621 non-institutionalized U.S. adult participants who reported “yes” to the subjective cognitive impairment question were considered, of whom 7,045 were men and 8,576 were women. …”
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“…SETTING/SUBJECT: Participants were patients with any advanced cancer diagnosis, recruited from Memorial Sloan Kettering Cancer Center (MSKCC), New York; Lincoln Medical Center (LMC), New York; and Ponce Health Science University (PHSU), Puerto Rico. MEASUREMENTS: Sociodemographic and semistructured interview. …”
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“…The methodology is tested in nine real-world time series collected in the Gulf of Alaska, Puerto Rico and Gibraltar (Spain), which are provided by the National Data Buoy Center (USA) and Puertos del Estado (Spain). …”
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“…Based on an ongoing study using RDS to recruit and study the interactions between HIV infection, injection drug use, and the microbiome in Puerto Rico, this paper explores the effectiveness of RDS during the pandemic and provided potential strategies that could improve recruitment and data collection. …”
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“…The vaccination of chimeric protein (15 μg) conferred complete protection against A/Puerto Rico/8/1934 (H1N1; PR8) in mice. It strongly induced influenza virus-specific antibody responses, cytotoxic T lymphocyte activity, and antibody-dependent cellular cytotoxicity. …”
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“…These can be used to explain post-eruptive phenomena and hazards to the local population, such as detected gases anomalies in La Bombilla and Puerto Naos. Our results have implications for understanding volcanic activity in the Canaries and volcano monitoring elsewhere, helping to support decision-making and providing significant insights into urban and infrastructure planning in volcanic areas.…”
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“…We characterized these two groups of caregivers using 2015-2019 Behavioral Risk Factor Surveillance System (BRFSS) data from the Caregiver Optional Module administered in 44 states, D.C., and Puerto Rico. Among 246,223 Module respondents, 21.3% reported providing care for a family member or friend. …”
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“…A re-evaluation of male monstrilloid specimens collected from two reef areas of the Mexican Caribbean allowed me to clarify the status of Monstrillamariaeugeniae Suárez-Morales & Islas-Landeros, 1993 and M.wandelii Stephensen, 1913 based on a comparison of males attributed to each of these species. Males from the Puerto Morelos reef system, northern Mexican Caribbean coast, were first proposed as a tropical subspecies of the subarctic M.wandelii; later on, morphologically close males collected from the Mahahual reef area, southern Mexican Caribbean coast, were designated as the males of M.mariaeugeniae. …”
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“…John and St. Thomas on the Puerto Rican Platform (PRP) and St. Croix, isolated by 2000 m deep water 45 km south of that platform. …”
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“…Regarding the quantitative assessment, it was found that the geosites Sumaco Volcano and Guagua Sumaco Lagoon and Outlook have a high scientific value, the geosite Pungarayacu Quarry has a high potential for educational use, and the Puerto Misahualli’s Bookcase has a high potential touristic use. …”
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“…The burdens due to active syndromes attributed to cocaine and pain relievers vary somewhat across subgroups. For the Puerto Rican subgroup, our estimates reveal potentially important burden reduction if active heroin dependence can be decreased. …”
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“…II showed IC(50) values of 0.07 and 0.09 μM for A/Puerto Rico/8/34 (H1N1) and 0.04 and 0.07 μM for A/Hong Kong/8/68 (H3N2), respectively. …”
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“…Three editions of WLIC have taken place in the region, being Cuba, Argentina, and Puerto Rico. So far, no Latin American president has been elected. …”
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