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  1. 3221
    “…The age-standardized weighted prevalence of current e-cigarette use varied across US states and territories, from 1.0% in Puerto Rico to 6.2% in Guam. After adjustment for demographic, socioeconomic, and lifestyle factors, including conventional cigarette use, the odds ratios of current e-cigarette use were 0.90 (95% CI, 0.83-0.98) for state laws prohibiting e-cigarette use in indoor areas of private workplaces, restaurants, and bars; 0.90 (95% CI, 0.85-0.95) for state laws requiring retailers to purchase a license to sell e-cigarettes; 1.04 (95% CI, 0.99-1.09) for state laws prohibiting self-service displays of e-cigarettes; 0.86 (95% CI, 0.74-0.99) for state laws prohibiting sales of tobacco products, including e-cigarettes, to persons younger than 21 years; and 0.89 (95% CI, 0.83-0.96) for state laws applying taxes to e-cigarettes. …”
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    Association of Electronic Cigarette Regulations With Electronic Cigarette Use Among Adults in the United States
  2. 3222
    “…Individuals aged 65 years or older and without dementia at baseline were selected from China, Cuba, the Dominican Republic, Mexico, Peru, Puerto Rico, and Venezuela. Dementia incidence was assessed over 3–5 years, with diagnosis according to the 10/66 Study diagnostic algorithm. …”
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    Prediction of dementia risk in low-income and middle-income countries (the 10/66 Study): an independent external validation of existing models
  3. 3223
    “…In the present study, various influenza H1, H3, H5, and H9 hemagglutinin (HA) proteins were expressed in insect cells, and then mice were subcutaneously immunized with the expressed HA proteins, and challenged by influenza A viruses (A/Puerto Rico/8/1934 (H1N1) or A/chicken/Guangdong/96 (H9N2)). …”
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    Recombinant influenza H1, H5 and H9 hemagglutinins containing replaced H3 hemagglutinin transmembrane domain showed enhanced heterosubtypic protection in mice
  4. 3224
    “…Non-invasive encapsulated follicular variant of papillary thyroid cancer (EFVPTC) was recently reclassified as non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFT-P).(1) In 2018, revised and stricter criteria were proposed for a lesion to qualify as NIFT-P including no well-formed papilla or BRAF-V600E mutation.(2) We are presenting an interesting case to highlight the importance of scrutinizing pathology slides to diagnose NIFTP with these more strict criteria. 35-year-old female from Puerto-Rico was diagnosed with Graves’ disease. After 2 years of methimazole treatment, total thyroidectomy was planned for definitive treatment of Graves’ disease. …”
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    SAT-461 NIFTP: A Painstaking Diagnosis Through the Pathologist’s Eyes
  5. 3225
    “…A lifetime non-smoker native to California, whose only significant travel history was in his 20s to Ecuador and Puerto Rico, areas endemic to Histoplasma. Abdominal CT showed large bilateral adrenal masses with intermediate density and low washout values (right: 4.9 cm, HU 45, absolute washout 30%; left: 4.8 cm, HU 30, absolute washout 25%). …”
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    SAT-221 50-Year-Old Fungus Suddenly Flourishes in Adrenal Glands: A Case of Sudden-Onset Bilateral Adrenal Masses Due to Latent Disseminated Histoplasmosis
  6. 3226
    “…RESULTS: In total, 6602 participant responses were recorded with representation from all U.S. 50 states, the District of Columbia, and Puerto Rico. The advertisements cumulatively reached 236,017 individuals and resulted in 9609 clicks (4.07% reach). …”
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    Social media as a recruitment platform for a nationwide online survey of COVID-19 knowledge, beliefs, and practices in the United States: methodology and feasibility analysis
  7. 3227
    por Alade, Azeez A., Buxo‐Martinez, Carmen J., Mossey, Peter A., Gowans, Lord J.J., Eshete, Mekonen A., Adeyemo, Wasiu L., Naicker, Thirona, Awotoye, Waheed A., Adeleke, Chinyere, Busch, Tamara, Toraño, Ada M., Bello, Carolina A., Soto, Mairim, Soto, Marilyn, Ledesma, Ricardo, Marquez, Myrellis, Cordero, Jose F., Lopez‐Del Valle, Lydia M., Salcedo, Maria I., Debs, Natalio, Li, Mary, Petrin, Aline, Olotu, Joy, Aldous, Colleen, Olutayo, James, Ogunlewe, Modupe O., Abate, Fekir, Hailu, Taye, Muhammed, Ibrahim, Gravem, Paul, Deribew, Milliard, Gesses, Mulualem, Hassan, Mohaned, Pape, John, Adeniyan, Oluwole A., Obiri‐Yeboah, Solomon, Arthur, Fareed K.N., Oti, Alexander A., Olatosi, Olubukola, Miller, Sara E., Donkor, Peter, Dunnwald, Martine M., Marazita, Mary L., Adeyemo, Adebowale A., Murray, Jeffrey C., Butali, Azeez
    Publicado 2020
    “…The current study was designed to update the list of IRF6 variants reported for VWS by compiling all the published mutations from 2013 to date as well as including the previously unreported VWS cases from Africa and Puerto Rico. METHODS: We used PubMed with the search terms; "Van der Woude syndrome," “Popliteal pterygium syndrome,” "IRF6," and "Orofacial cleft" to identify eligible studies. …”
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    Non‐random distribution of deleterious mutations in the DNA and protein‐binding domains of IRF6 are associated with Van Der Woude syndrome
  8. 3228
    “…DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used data from the Sister Study, a prospective cohort study comprising 50 884 women living in the US and Puerto Rico aged 35 to 74 years at enrollment who had a sister with breast cancer but had not had breast cancer themselves. …”
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    Association of Neighborhood Deprivation With Epigenetic Aging Using 4 Clock Metrics
  9. 3229
    “…DESIGN, SETTING, AND PARTICIPANTS: This repeated, cross-sectional study conducted across all 50 states, the District of Columbia, and Puerto Rico used a convenience sample of residual serum specimens provided by persons of all ages that were originally submitted for routine screening or clinical management from 2 private clinical commercial laboratories. …”
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    Estimated SARS-CoV-2 Seroprevalence in the US as of September 2020
  10. 3230
    “…METHODS: C57BL/6 mice with or without CS exposure for 6 weeks were inoculated intranasally with a single, non-lethal dose of the influenza A virus (IAV) A/Puerto Rico/8/1934 (PR8) strain. At 7 and 10 days after infection, lung and mediastinal lymph nodes (MLN) cells were collected to determine the numbers of total CD4 + and CD8 + T cells, and IAV-specific CD4 + and CD8 + T cells, using flow cytometry. …”
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    Long-term cigarette smoke exposure dysregulates pulmonary T cell response and IFN-γ protection to influenza virus in mouse
  11. 3231
    por Degenhardt, Frauke, Mayr, Gabriele, Wendorff, Mareike, Boucher, Gabrielle, Ellinghaus, Eva, Ellinghaus, David, ElAbd, Hesham, Rosati, Elisa, Hübenthal, Matthias, Juzenas, Simonas, Abedian, Shifteh, Vahedi, Homayon, Thelma, B K, Yang, Suk-Kyun, Ye, Byong Duk, Cheon, Jae Hee, Datta, Lisa Wu, Daryani, Naser Ebrahim, Ellul, Pierre, Esaki, Motohiro, Fuyuno, Yuta, McGovern, Dermot P B, Haritunians, Talin, Hong, Myhunghee, Juyal, Garima, Jung, Eun Suk, Kubo, Michiaki, Kugathasan, Subra, Lenz, Tobias L, Leslie, Stephen, Malekzadeh, Reza, Midha, Vandana, Motyer, Allan, Ng, Siew C, Okou, David T, Raychaudhuri, Soumya, Schembri, John, Schreiber, Stefan, Song, Kyuyoung, Sood, Ajit, Takahashi, Atsushi, Torres, Esther A, Umeno, Junji, Alizadeh, Behrooz Z, Weersma, Rinse K, Wong, Sunny H, Yamazaki, Keiko, Karlsen, Tom H, Rioux, John D, Brant, Steven R, Franke, Andre
    Publicado 2021
    “…We performed a comprehensive fine mapping of single HLA alleles in UC in a cohort of 9272 individuals with African American, East Asian, Puerto Rican, Indian and Iranian descent and 40 691 previously analyzed Caucasians, additionally analyzing whole HLA haplotypes. …”
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    Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations
  12. 3232
    “…The study cohort included 4768 male residents (62.1%), 2698 female residents (35.1%), 4919 non-Hispanic White residents (64.0%), 2620 residents from other racial/ethnic groups (Alaska Native, American Indian, Asian or Pacific Islander, African American, Mexican American, Native Hawaiian, Puerto Rican, other Hispanic, or mixed or other race) (34.1%), 483 residents who identified as lesbian, gay, bisexual, transgender, queer, or other (LGBTQ+) (6.3%), and 5951 residents who were married or in a relationship (77.5%). …”
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    Prevalence of Discrimination, Abuse, and Harassment in Emergency Medicine Residency Training in the US
  13. 3233
    “…RESULTS: Between 2014 and 2017, Paraguay and Venezuela had the highest mortality rates of cervical cancer, whereas Puerto Rico had the lowest rates. Overall, most of the LAC countries showed downward trends of cervical cancer mortality over the entire period. …”
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    Cervical cancer mortality among young women in Latin America and the Caribbean: trend analysis from 1997 to 2030
  14. 3234
    “…METHODS: This study (qualitative and quantitative phases) was carried out between September 2015 and November 2016; women residing in the border towns of Leticia and Puerto Nariño participated in it. The first phase (qualitative) involved interviews and focus group discussions; this led to establishing factors related to CC P&P programme attendance which were used in the quantitative phase for designing a survey for determining the strength of association in a logistic regression model. …”
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    Cervical cancer screening programme attendance and compliance predictors regarding Colombia’s Amazon region
  15. 3235
    “…Department Of Corrections websites and press releases) for 53 US prison systems, including all states, Immigration and Customs Enforcement, the Federal Bureau of Prisons, and Puerto Rico. Coders reviewed if states had prison labor policies, if states had COVID-19 specific prison labor policies, the location of work, industries both pre- and during the COVID-19 pandemic, the scope of work, and hourly wage. …”
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    Incarcerated workers: overlooked as essential workers
  16. 3236
    “…DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study included adult men and women who enrolled in the Cancer Prevention Study-3 at American Cancer Society community events in 35 US states, the District of Columbia, and Puerto Rico between 2006 and 2013. Participants completed a validated food frequency questionnaire between 2015 and 2017. …”
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    Association of Socioeconomic and Geographic Factors With Diet Quality in US Adults
  17. 3237
    “…In addition, in January 2019, penguins found dead in the reproducing colony in four islands localized in Puerto Deseado City (Santa Cruz, Patagonian, Argentina - 47°45′00″S 65°55′00″W) were collected. …”
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    P465 Aspergillosis in free-ranging Magellanic penguins
  18. 3238
    “…In this study, we calculated levels of TTK, p-TBK1, epithelial (E-cadherin), mesenchymal (Vimentin), and proliferation (Ki67) markers through immunohistochemical (IHC) staining of breast cancer tissue microarrays (TMAs) that includes samples from 6 regions in the Southeast of the United States and Puerto Rico -regions enriched with NHB and H/L breast cancer patients. …”
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    Ethnic and racial-specific differences in levels of centrosome-associated mitotic kinases, proliferative and epithelial-to-mesenchymal markers in breast cancers
  19. 3239
    “…DESIGN, SETTING, AND PARTICIPANTS: A cross-sectional study of adult MSM in the 2017 National HIV Behavioral Surveillance system, which used venue-based sampling methods to collect data related to HIV testing, receipt of prevention services, and risk factors for HIV, was conducted at 588 venues in 23 urban areas in the contiguous US and Puerto Rico. All participants were offered HIV testing. …”
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    HIV Self-testing and Risk Behaviors Among Men Who Have Sex With Men in 23 US Cities, 2017
  20. 3240
    “…ALLHAT recruited participants (n = 25516) from 625 primary care settings throughout the United States, Canada, Puerto Rico, and United States Virgin Islands, aged 55 and older with hypertension and at least one additional risk factor for heart disease. aTRH was assessed from the year 2 visit. …”
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    Pharmacoepidemiologic study of association between apparent treatment resistant hypertension, cardiovascular disease and interaction effect by sex and age
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