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  1. 301
    por Gu, Liubao, Kitamura, Masanori
    Publicado 2012
    “…The induction of SASP-RAP by senescence was similarly observed in natural replicative senescence. …”
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    Online Artículo Texto
    Sensitive Detection and Monitoring of Senescence-Associated Secretory Phenotype by SASP-RAP Assay
  2. 302
    “…Furthermore, Rap1 activation is required for EGFR-mediated metastasis in vivo without impacting primary tumor growth. …”
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    EGFR-dependent pancreatic carcinoma cell metastasis via Rap1 activation
  3. 303
    “…Rap1-GTP activates leukocyte function-associated antigen-1 (LFA-1) to induce arrest on the high endothelial venule (HEV). …”
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    Dual functions of Rap1 are crucial for T-cell homeostasis and prevention of spontaneous colitis
  4. 304
    “…As a first step in addressing this question, we present phenotypes of murine total and vascular-specific Rap1a, Rap1b and double Rap1a and Rap1b (Rap1) knockout (KO) mice. …”
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    Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature
  5. 305
    “…RAP80 localizes to sites of DNA insults to enhance the DNA-damage responses. …”
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    Online Artículo Texto
    TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
  6. 306
    “…Here, we showed that EMT is induced by the downregulation of RAP80, a well‐known regulator for DNA damage response. …”
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    RAP80 regulates epithelial–mesenchymal transition related with metastasis and malignancy of cancer
  7. 307
    “…Here, we report the identification of the small GTPase Rap1 as a conserved binding partner of the TORC2 component RIP3/SIN1, and that Rap1 positively regulates the RasC-mediated activation of TORC2 in Dictyostelium. …”
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    The small GTPases Ras and Rap1 bind to and control TORC2 activity
  8. 308
    “…RAP1 remains more stable compared to TRF2. RAP1 also responds to oxidative stress, but the response is different to that observed in aging.…”
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    Telomere protein RAP1 levels are affected by cellular aging and oxidative stress
  9. 309
    “…In this study, we developed a novel affinity tag called the “RAP tag” system, which comprises a mouse antirat podoplanin monoclonal antibody (clone PMab-2) and the RAP tag (DMVNPGLEDRIE). …”
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    Development of RAP Tag, a Novel Tagging System for Protein Detection and Purification
  10. 310
    “…In phylogenetically diverse bacteria, the conserved protein RapZ plays a central role in RNA-mediated regulation of amino-sugar metabolism. …”
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    Structural insights into RapZ-mediated regulation of bacterial amino-sugar metabolism
  11. 311
    “…One of them is the conserved CDK5RAP2 protein. Here we focus on the role of Dictyostelium CDK5RAP2 for maintenance of centrosome integrity, its interaction partners and its dynamic behavior during interphase and mitosis. …”
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    CDK5RAP2 Is an Essential Scaffolding Protein of the Corona of the Dictyostelium Centrosome
  12. 312
    “…Knockdown of endogenous CDK5RAP3 in Caki-1 slightly increased cell viability, whereas overexpression of CDK5RAP3 in 769-P cells inhibited cell viability. …”
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    CDK5RAP3 Participates in Autophagy Regulation and Is Downregulated in Renal Cancer
  13. 313
    “…Recent studies have uncovered that in yeast, the transcription factor Rap1 restricts transcription in the divergent direction and thereby controls promoter directionality. …”
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    Online Artículo Texto
    Transcribe this way: Rap1 confers promoter directionality by repressing divergent transcription
  14. 314
    “…As a case study, we have turned to rap lyrics, an established sub-genre of present-day popular music, known for its explicit content and unique rhythmical delivery of lyrics. …”
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    Keepin’ it real: Linguistic models of authenticity judgments for artificially generated rap lyrics
  15. 315
    “…OBJECTIVE: Rap2c is a member of the Ras superfamily that has been implicated in various types of cancers. …”
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    Online Artículo Texto
    Rap2c as a Novel Biomarker for Predicting Poor Prognosis in Glioma
  16. 316
    “…Here, we investigated the application potential of RAP in modulating fruit colours by overexpression of RAP in F. vesca and knockout of RAP in the cultivated strawberry Fragaria × ananassa. …”
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    Genetic modulation of RAP alters fruit coloration in both wild and cultivated strawberry
  17. 317
    “…Incorporating reclaimed asphalt pavement (RAP) into asphalt mixtures achieves astonishingly environmental and economic benefits. …”
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    Performance Characterization of Hot Mix Asphalt with High RAP Content and Basalt Fiber
  18. 318
    “…However, the function of Rap2B in hepatocellular carcinoma (HCC) remains unclear. …”
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    Knockdown of Rap2B Inhibits the Proliferation and Invasion in Hepatocellular Carcinoma Cells
  19. 319
    “…Furthermore, Cdk5rap3 is highly expressed in mature Paneth cells. …”
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    Cdk5rap3 is essential for intestinal Paneth cell development and maintenance
  20. 320
    “…The RNA binding domain abundant in apicomplexans (RAP) is a protein domain identified in a diverse group of proteins, called RAP proteins, many of which have been shown to be involved in RNA binding. …”
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    Identification and phylogenetic analysis of RNA binding domain abundant in apicomplexans or RAP proteins
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