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Mostrando 381 - 400 Resultados de 4,104 Para Buscar '"rap"', tiempo de consulta: 0.27s Limitar resultados
  1. 381
    “…Overexpression of Rap1b restores the effects of USP32 knockdown, which further verifies our hypothesis. …”
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    Roles of the hsa_circ_0013880/USP32/Rap1b axis in the proliferation and apoptosis of acute myeloid leukemia cells: hsa_circ_0013880/USP32/Rap1b in acute myeloid leukemia
  2. 382
    Publicado 2008
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    CERN; Prima del via a LHC rispettata lunga tradizione con un 'rap'
  3. 383
    Publicado 2008
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    CERN; Prima del via a LHC rispettata lunga tradizione con un 'rap'
  4. 384
    “…In accordance, data collected from pull-down experiments designed to identify only the active form of Rap1b (Rap1b-GTP), and infection assays using cells transfected with a constitutively active mutant of Rap1b (Rap1b-G12V), strongly suggest the participation of Rap1b as mediator of the pathway. …”
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    Host Cell Rap1b mediates cAMP-dependent invasion by Trypanosoma cruzi
  5. 385
    “…Through NMR structural analysis, we unexpectedly identify an RNA Recognition Motif (RRM) in TbRAP1, which is unprecedented for RAP1 homologs. …”
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    The RRM-mediated RNA binding activity in T. brucei RAP1 is essential for VSG monoallelic expression
  6. 386
    “…The mRNA expression for IL1RAP, the IL1RL1 co‐receptor, was greatest in severe neutrophilic and mixed granulocytic asthma. …”
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    IL1RAP expression and the enrichment of IL‐33 activation signatures in severe neutrophilic asthma
  7. 387
    por Bondra, Eliana R, Rine, Jasper
    Publicado 2023
    “…We also found that promoter-bound Rap1 activated HMLα when in an expressed state, and aided in the transition from transcription initiation to elongation. …”
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    Context dependent function of the transcriptional regulator Rap1 in gene silencing and activation in Saccharomyces cerevisiae
  8. 388
    por Bondra, Eliana R., Rine, Jasper
    Publicado 2023
    “…We also found that promoter-bound Rap1 activated HMLα when in an expressed state, and aided in the transition from transcription initiation to elongation. …”
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    Context-dependent function of the transcriptional regulator Rap1 in gene silencing and activation in Saccharomyces cerevisiae
  9. 389
    “…RAP80 has been characterized as a component of the BRCA1-A complex and is responsible for the recruitment of BRCA1 to DNA double-strand breaks (DSBs). …”
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    RAP80 phase separation at DNA double-strand break promotes BRCA1 recruitment
  10. 390
    “…The centrosomal protein, CDK5RAP2, is mutated in primary microcephaly, a neurodevelopmental disorder characterized by reduced brain size. …”
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    CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response
  11. 391
    “…Rap1 GTPases control immune synapse formation and signaling in lymphocytes. …”
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    Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes
  12. 392
    “…RhoL mediates Integrin adhesion caused by Drosophila Rap1 over-expression and moves Rap1 away from a cytoplasmic concentration to the leading edge during invasive migration. …”
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    RhoL controls invasion and Rap1 localization during immune cell transmigration in Drosophila
  13. 393
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    “The Roaring Adventures of Puff” (RAP) – a school based asthma education program for children with asthma
  14. 394
    “…Rap1 is slightly enriched at the apical pole of metaphase/anaphase NBs and was found in a complex with atypical protein kinase C and Par6 in vivo. …”
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    The Rap1–Rgl–Ral signaling network regulates neuroblast cortical polarity and spindle orientation
  15. 395
    “…Previous work from our laboratory showed that sustained stimulation of Rap1 by 8-pCPT-2'-O-Me-cAMP (8CPT) via activation of Epac, a Rap1 GEF, or by expression of a constitutively active Rap1 mutant (cRap1) suppresses endothelial cell chemotaxis and subsequent angiogenesis. …”
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    A Novel Interplay between Rap1 and PKA Regulates Induction of Angiogenesis in Prostate Cancer
  16. 396
    “…Previously we demonstrated the GTPase Rap2 to be a regulator of LFA-1-mediated migration. …”
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    A role for Rap2 in recycling the extended conformation of LFA-1 during T cell migration
  17. 397
    “…Interestingly, the sequence of the binding site for Rap1 at the silencers is distinct from the genome-wide binding profile of Rap1, being a weaker match to the consensus, and indeed is bound with low affinity relative to the consensus sequence. …”
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    The Enigmatic Conservation of a Rap1 Binding Site in the Saccharomyces cerevisiae HMR-E Silencer
  18. 398
    “…RESULTS: Monastrol induced unprenylated Rap1A in intracellular Leishmania when exposed to this anticancer drug at the IC(50) (10 μM). …”
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    A member of the Ras oncogene family, RAP1A, mediates antileishmanial activity of monastrol
  19. 399
    por Kitagishi, Yasuko, Matsuda, Satoru
    Publicado 2013
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    RUFY, Rab and Rap Family Proteins Involved in a Regulation of Cell Polarity and Membrane Trafficking
  20. 400
    “…Plexin stabilizes the switch II region of Rap in an unprecedented conformation, bringing Gln63 in Rap into the active site for catalyzing GTP hydrolysis. …”
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    Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin
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