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  1. 401
    “…RESULTS: Through a user friendly web interface, the RAP workflow can be suitably customized by the user and it is automatically executed on our cloud computing environment. …”
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    RAP: RNA-Seq Analysis Pipeline, a new cloud-based NGS web application
  2. 402
    “…The purpose of this study is to explore the advantages and clinical effect of the rap stress stimulator applied for open crus fracture after skeletal external fixation. …”
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    Clinical analysis of the rap stress stimulator applied for crus fracture after skeletal external fixation
  3. 403
    “…Rap1 recruits Rif1 and Rif2 to telomeres, but neither Rif1 nor Rif2 is required for DSB induction. …”
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    Binding of Multiple Rap1 Proteins Stimulates Chromosome Breakage Induction during DNA Replication
  4. 404
    “…Rap1A is a member of small G proteins belonging to the Ras family. …”
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    Rap1A Regulates Osteoblastic Differentiation via the ERK and p38 Mediated Signaling
  5. 405
    “…In fission yeast, telomeres localize to the nuclear periphery via interaction of the telomeric protein Rap1 with the membrane protein Bqt4. During meiotic prophase, the meiotic proteins Bqt1-2 bind Rap1 and tether to the spindle pole body to form the bouquet. …”
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    Telomere protein Rap1 is a charge resistant scaffolding protein in chromosomal bouquet formation
  6. 406
    “…Availability and implementation: RapMap is implemented in C ++11 and is available as open-source software, under GPL v3, at https://github.com/COMBINE-lab/RapMap. …”
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    RapMap: a rapid, sensitive and accurate tool for mapping RNA-seq reads to transcriptomes
  7. 407
    “…Here, we report the critical role of Cdk5rap2 in maintaining the germ cell pool during embryonic development. …”
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    CDK5RAP2 Is Required to Maintain the Germ Cell Pool during Embryonic Development
  8. 408
    “…USP13, in turn, deubiquitinates RAP80 and promotes RAP80 recruitment and proper DDR. …”
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    USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response
  9. 409
    “…Here we show structurally that talin-F0 binds to human Rap1b like canonical Rap1 effectors despite little sequence homology, and disruption of the binding strongly impairs integrin activation, cell adhesion, and cell spreading. …”
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    Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation
  10. 410
    “…RAP1 is part of shelterin, the protective complex at telomeres. …”
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    RAP1 Protects from Obesity through Its Extratelomeric Role Regulating Gene Expression
  11. 411
    “…In this context, we find the Rap1-GEF Dizzy is enriched at the ZA and our results suggest that it promotes Rap1 activity during ZA morphogenesis. …”
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    Rap1, Canoe and Mbt cooperate with Bazooka to promote zonula adherens assembly in the fly photoreceptor
  12. 412
    “…This paper introduces a five-step framework, namely the Robust Adaptation Planning (RAP) framework, to plan and respond to the ‘grand challenge’ of climate change. …”
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    Applying the robust adaptation planning (RAP) framework to Ghana’s agricultural climate change adaptation regime
  13. 413
    “…Residue network analysis shows that the phosphorylation of Rap results in a community spanning both Rap and RBD and strongly suggests transmission of allosteric effects of local alterations in Rap to distal regions of RBD, potentially affecting the downstream signalling. …”
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    Phosphorylation promotes binding affinity of Rap-Raf complex by allosteric modulation of switch loop dynamics
  14. 414
    “…RESULTS: The newly identified inhibitors of the Rap1-Pde6δ interaction counteract AD phenotypes, by reconfiguring Rap1 signalling underlying synaptic efficacy, Ca(2+) influx, and neuronal repolarisation, without adverse effects in-cellulo or in-vivo. …”
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    Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer’s disease
  15. 415
    “…Fourth, the results of an activating Rap1 pull-down assay indicated that TBC1D21 overexpression inactivates Rap1 activity in cell models. …”
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    TBC1D21 Potentially Interacts with and Regulates Rap1 during Murine Spermatogenesis
  16. 416
    “…Telomeres located at the ends of linear chromosomes play important roles in the maintenance of life. Rap1, a component of the shelterin telomere protein complex, interacts with multiple proteins to perform various functions; further, formation of shelterin requires Rap1 binding to other components such as Taz1 and Poz1, and telomere tethering to the nuclear envelope (NE) involves interactions between Rap1 and Bqt4, a nuclear membrane protein. …”
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    Casein kinase 2 regulates telomere protein complex formation through Rap1 phosphorylation
  17. 417
    “…RAP1 is a well-known telomere-binding protein, but its functions in human stem cells have remained unclear. …”
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    Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis
  18. 418
    “…Here, we evaluate the connection between CDK5RAP3 and MCM6 using mass spectrometry and immunoprecipitation. …”
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    CDK5RAP3 Inhibits the Translocation of MCM6 to Influence the Prognosis in Gastric Cancer
  19. 419
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    The retroclavicular approach to the PECS II (RAP) block: a novel regional technique for breast surgery
  20. 420
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    Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1
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