Mostrando 41 - 60 Resultados de 4,104 Para Buscar '"rap"', tiempo de consulta: 0.11s Limitar resultados
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    “…This review addresses the issue of the numerous roles played by Rap1 GTPase (guanosine triphosphatase) in different cell types, in terms of both physiology and pathology. …”
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  3. 43
    “…Rap1 acts as an effector of Ca(2+) signaling when activated by mechanisms involving Ca(2+) and DAG-activated (CalDAG-) GEFs. …”
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    “…RAP1 is one of the components of shelterin, the capping complex at chromosome ends or telomeres, although its role in telomere length maintenance and protection has remained elusive. …”
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    “…During the various stages of barrier dynamics, different guanine nucleotide exchange factors (GEFs) control Rap1 activity, indicating that Rap1 integrates multiple input signals. …”
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  17. 57
    “…The telomere regulator and transcription factor Rap1 is the only telomere protein conserved in yeasts and mammals. …”
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  18. 58
    “…Our findings uncover the primary role of VMH Rap1 in glycemic control and implicate Rap1 signaling as a potential target for therapeutic intervention in diabetes.…”
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  19. 59
    “…As the activation of both Rap1 and Rap2 was significantly decreased under SMG, the expression of Rap1GEF1 (C3G) and Rap1GAP in HUVECs, which regulate the activation of them, was further determined. …”
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  20. 60
    “…Successful hematopoietic cell transplantation (HCT) depends on rapid engraftment of the progenitor and stem cells that will reestablish hematopoiesis. Rap1A and Rap1B are two closely related small GTPases that may affect platelet and neutrophil engraftment during HCT through their roles in cell adhesion and migration. β-adrenergic signaling may regulate the participation of Rap1A and Rap1B in engraftment through their inhibition or activation. …”
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