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  1. 2101
    por Aguero, Stephanie, Terreux, Raphaël
    Publicado 2019
    “…In this study, we used a rational design strategy for improving the specificity of the nitroreductase from E. …”
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    Degradation of High Energy Materials Using Biological Reduction: A Rational Way to Reach Bioremediation
  2. 2102
    “…OBJECTIVE: The objective of this study was to isolate proteolytic microorganisms and evaluate their effects on proteolysis in total mixed ration (TMR) silages of soybean curd residue. METHODS: TMRs were formulated with soybean curd residue, alfalfa or Leymus chinensis hay, corn meal, soybean meal, a vitamin-mineral supplement, and salt in a ratio of 25.0: 40.0:30.0:4.0:0.5:0.5, respectively, on a basis of dry matter. …”
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    Characteristics of proteolytic microorganisms and their effects on proteolysis in total mixed ration silages of soybean curd residue
  3. 2103
    “…Our findings support rationally designed AHR agonists for IBD therapy.…”
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    Modulation of lymphocyte-mediated tissue repair by rational design of heterocyclic aryl hydrocarbon receptor agonists
  4. 2104
    “…However, due to lack of fundamental knowledge on α-C–H bond strength as an energetic guideline, rational exploration of new synthetic methodologies remains a far-reaching anticipation. …”
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    Toward Rational Understandings of α-C–H Functionalization: Energetic Studies of Representative Tertiary Amines
  5. 2105
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    Rational design of a DNA sequence-specific modular protein tag by tuning the alkylation kinetics
  6. 2106
    “…These concerns have resulted in initiatives to better manage the entry of new medicines and enhance the rational use of medicines (RUM). However, there is a need to ascertain the current situation. …”
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    Mapping of Current Obstacles for Rationalizing Use of Medicines (CORUM) in Europe: Current Situation and Potential Solutions
  7. 2107
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    Rationally assembled albumin/indocyanine green nanocomplex for enhanced tumor imaging to guide photothermal therapy
  8. 2108
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    Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins
  9. 2109
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    Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines
  10. 2110
    por Binkley, Charles E., Kemp, David S.
    Publicado 2020
    “…It is recognized that unless the supply of PPE is quickly replenished, or viable alternatives to traditional equipment are devised in the coming days to weeks, hospitals and healthcare systems will face the difficult task of rationing PPE to at-risk clinicians. This paper suggests an ethical framework for that process.…”
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    Ethical Rationing of Personal Protective Equipment to Minimize Moral Residue During the COVID-19 Pandemic
  11. 2111
    “…The ensilage of total mixed ration (TMR) is a technology designed to help farmers with limitations to provide a balanced diet for their herds. …”
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    Effects of holes in plastic film on the storage losses in total mixed ration silage in round bales
  12. 2112
    “…BACKGROUND: Good dispensing practice is vital for rational use of medicines. There are many paediatric specific challenges when maintaining good dispensing practices to children. …”
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    Rational dispensing of oral dosage forms of medicines to children at a teaching hospital in Sri Lanka
  13. 2113
    “…In this Minireview, we summarize the recent progress of the OFET‐based protein assays including the rational design strategies for devices and sensing materials.…”
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    Protein Assays on Organic Electronics: Rational Device and Material Designs for Organic Transistor‐Based Sensors
  14. 2114
    “…METHODS: This Delphi survey was organized within the Rational Use of Analgesics (RUA) Group projects to reach a consensus among Italian palliative care specialists on pain assessment and management. …”
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    Cancer Pain Management: An Italian Delphi Survey from the Rational Use of Analgesics (RUA) Group
  15. 2115
    “…We make the first effort to summarize these measurement models and to evaluate rationality of the common scoring methods of the IRI by confirmatory factor analysis, focusing on model fitting, factor loading, and model-based reliability simultaneously. …”
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    Investigation on the Rationality of the Extant Ways of Scoring the Interpersonal Reactivity Index Based on Confirmatory Factor Analysis
  16. 2116
    “…Here, we report a successful case of theory-guided rational design of a much higher performance In(2)O(3) nanocatalyst. …”
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    Rationally designed indium oxide catalysts for CO(2) hydrogenation to methanol with high activity and selectivity
  17. 2117
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    Rational Design of the Platinahelicene Enantiomers for Deep-Red Circularly Polarized Organic Light-Emitting Diodes
  18. 2118
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    Countermeasures to Coronavirus Disease 2019: Are Immunomodulators Rational Treatment Options—A Critical Review of the Evidence
  19. 2119
    por Schaller, David, Wolber, Gerhard
    Publicado 2020
    “…Furthermore, PyRod pharmacophores demonstrate higher sensitivity than ligand‐based pharmacophores and deliver structural insights, which are key to rational lead optimization.…”
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    PyRod Enables Rational Homology Model‐based Virtual Screening Against MCHR1
  20. 2120
    “…We gather here, a set of information, and made predictions aiming to provide a tool for supporting the rational design of more efficient β-glucosidases. We hope that Glutantβase can help improve second-generation biofuel production. …”
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    Glutantβase: a database for improving the rational design of glucose-tolerant β-glucosidases
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