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  1. 2201
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    Nanophysical Antimicrobial Strategies: A Rational Deployment of Nanomaterials and Physical Stimulations in Combating Bacterial Infections
  2. 2202
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    A rational synthesis of ultrasmall palladium-based alloys with superhydrophilicity as biocompatible agents and recyclable catalysts
  3. 2203
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    Rational design of stapled peptides targeting phosphorylated GSK3β for regulating osteoclast differentiation
  4. 2204
    “…The results provide a theoretical base for the rational design and screening of the Ag-based core–shell catalysts for clean energy conversion and storage.…”
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    Rational design of efficient transition metal core–shell electrocatalysts for oxygen reduction and evolution reactions
  5. 2205
    “…In the current study, rational engineering of guide RNAs (gRNAs) is performed to develop small-molecule-responsive CRISPR/Cas9. …”
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    Rational guide RNA engineering for small-molecule control of CRISPR/Cas9 and gene editing
  6. 2206
    “…The study demonstrates that thermally stable mutants of CRL could be identified with limited experimental efforts using rational design methods.…”
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    Identification of a hot-spot to enhance Candida rugosa lipase thermostability by rational design methods
  7. 2207
    “…Because of the drawbacks of cytarabine (Ara-C) such as poor lipid solubility, deamination inactivation and low oral bioavailability limiting its application by oral administration, herein we propose a novel amphiphilic low molecular weight cytarabine prodrug (PA-Ara) by conjugating palmitic acid (PA) to Ara-C, making it possible to avoid the deamination inactivation by protecting the active 4-amino, as well as improving lipid solubility. Thanks to the rational design, the oil/water partition coefficient (P) of PA-Ara was improved tremendously compared with Ara-C, and the PA-Ara conjugation was stable enough in artificial digestive juice, ensuring that most molecules could be absorbed in the form of the prodrug. …”
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    Rational design of a new cytarabine-based prodrug for highly efficient oral delivery of cytarabine
  8. 2208
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    The European Prescribing Exam: assessing whether European medical students can prescribe rationally and safely
  9. 2209
    por Balkıs, Murat, Duru, Erdinç
    Publicado 2022
    “…The participants completed measures of negative life events, psychological distress, and irrational/rational beliefs. The present findings indicated that adverse life events associated with COVID-19 predict psychological distress in adults. …”
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    Negative Life Events Associated with COVID-19 and Psychological Distress: The Role of Irrational and Rational Beliefs
  10. 2210
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    Kinetic Rationalization of Nonlinear Effects in Asymmetric Catalytic Cascade Reactions under Curtin–Hammett Conditions
  11. 2211
    “…Based on the Stimulus–Organism–Response (S-O-R) model, this study divides the route affecting organic consumption behavior into the rational route and emotional route. It was proved that the emotional route (positive emotion) has a greater impact on the purchase intention of organic food than the rational route (perceived social value). …”
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    Pull the Emotional Trigger or the Rational String? A Multi-Group Analysis of Organic Food Consumption
  12. 2212
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    Rational Engineering of Non-Ubiquinone Containing Corynebacterium glutamicum for Enhanced Coenzyme Q(10) Production
  13. 2213
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    Rational Engineering of Anode Current Collector for Dendrite-Free Lithium Deposition: Strategy, Application, and Perspective
  14. 2214
    “…AMP development for clinical use has been mostly limited to topical application to date. We developed a rational framework for systematically addressing this challenge using libraries composed of 86 novel Trp- and Arg-rich engineered peptides tested against clinical strains of the most common multidrug-resistant bacteria known as ESKAPE pathogens. …”
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    Rational Framework for the Design of Trp- and Arg-Rich Peptide Antibiotics Against Multidrug-Resistant Bacteria
  15. 2215
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    Anti-double stranded DNA antibodies: A rational diagnostic approach in limited-resource settings
  16. 2216
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    Inhibiting UCH-L5: Rational Design of a Cyclic Ubiquitin-Based Peptide Inhibitor
  17. 2217
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    Rational Design and Characterisation of Novel Mono- and Bimetallic Antibacterial Linde Type A Zeolite Materials
  18. 2218
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    Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists
  19. 2219
    “…By constructing the STIRPAT model, this paper quantitatively analyzes the impact of industrial structure rationalization and upgrade on carbon emissions. The results show that the rationalization and upgrading of industrial structure in the Beijing-Tianjin-Hebei urban agglomeration significantly inhibit carbon emissions. …”
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    The Impact of Rationalization and Upgrading of Industrial Structure on Carbon Emissions in the Beijing-Tianjin-Hebei Urban Agglomeration
  20. 2220
    “…Here, we describe the structure-based rational design of the enhanced FAST mutants, optimized for the N871b fluorogen. …”
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    Structure-based rational design of an enhanced fluorogen-activating protein for fluorogens based on GFP chromophore
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