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  1. 2301
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    A rational use of glucocorticoids in patients with early arthritis has a minimal impact on bone mass
  2. 2302
    por Chen, Li-Tzu, Wang, Andrew H.-J.
    Publicado 2010
    “…Here, we report that a rationally-designed small peptide based on the crystal structure of Escherichia coli RecA–DNA complex can promote homologous recombination through the enhancement of both RecA-mediated strand assimilation and three-strand exchange activity. …”
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    A rationally designed peptide enhances homologous recombination in vitro and resistance to DNA damaging agents in vivo
  3. 2303
    por Bryksin, Anton V., Matsumura, Ichiro
    Publicado 2010
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    Rational Design of a Plasmid Origin That Replicates Efficiently in Both Gram-Positive and Gram-Negative Bacteria
  4. 2304
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    Human Umbilical Cord Blood Stem Cells: Rational for Use as a Neuroprotectant in Ischemic Brain Disease
  5. 2305
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    General aptitude and the assumption of truth in deductively rational reasoning about probable but false antecedent to consequent relations
  6. 2306
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    Improving Rational Treatment of Malaria: Perceptions and Influence of RDTs on Prescribing Behaviour of Health Workers in Southeast Nigeria
  7. 2307
    “…BACKGROUND: In the last 30 years concepts in pharmacology have moved from Essential Medicines (EM) to P-drugs via the Rational Use of Medicines (RUM), but no structured study has evaluated the level of understanding among the working clinicians about these concepts. …”
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    Current scenario of attitude and knowledge of physicians about rational prescription: A novel cross-sectional study
  8. 2308
    “…This study validates a novel, entirely rational approach for the design of capsid assembly interfacial inhibitors that show antiviral activity.…”
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    Rationally Designed Interfacial Peptides Are Efficient In Vitro Inhibitors of HIV-1 Capsid Assembly with Antiviral Activity
  9. 2309
    “…The aim of the South Asian Consensus Guidelines is to provide evidence-based recommendations to assist healthcare providers in the rational management of type 2 diabetes mellitus in patients with HIV. …”
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    South Asian Consensus Guidelines for the rational management of diabetes in human immunodeficiency virus/acquired immunodeficiency syndrome
  10. 2310
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    Targeting tumor angiogenesis with TSP-1-based compounds: rational design of antiangiogenic mimetics of endogenous inhibitors
  11. 2311
    “…At least 97% of TKR patients in England have more severe symptoms than the thresholds we have identified, suggesting that further rationing by OKS is probably unjustified. TRIAL REGISTRATION NUMBER: ISRCTN 45837371.…”
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    Rationing of total knee replacement: a cost-effectiveness analysis on a large trial data set
  12. 2312
    “…However, once selected into treatment, attempts were made to ration-out complementary services more equitably. …”
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    NGO-provided free HIV treatment and services in Burkina Faso: scarcity, therapeutic rationality and unfair process
  13. 2313
    “…In line with the secretome concept, a rational and original analytical strategy mimicking the secretion steps that determine ultimate SCL was developed for Gram-positive (monoderm) bacteria. …”
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    Subcellular Localization of Extracytoplasmic Proteins in Monoderm Bacteria: Rational Secretomics-Based Strategy for Genomic and Proteomic Analyses
  14. 2314
    “…The SINERGIE (South Italian Network for Rational Guidelines and International Epidemiology) project is intended to set up a collaborative network comprising virologists, clinicians and public health officials dealing with patients affected by HCV disease in the Calabria Region. …”
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    Future research and collaboration: the “SINERGIE” project on HCV (South Italian Network for Rational Guidelines and International Epidemiology)
  15. 2315
    por Nagy, Gabor, Oostenbrink, Chris
    Publicado 2012
    “…Here we use prolonged simulation time and Hamiltonian replica exchange to overcome the inconsistencies, and give a possible rationalization of the phenomenon at a molecular level. …”
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    Rationalization of stereospecific binding of propranolol to cytochrome P450 2D6 by free energy calculations
  16. 2316
    “…Re-framing future interventions and policies to support rational and informed individual patient choices, is the way forward to realising the full potential health and economic benefits from the efficacious use of medications.…”
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    Understanding rational non-adherence to medications. A discrete choice experiment in a community sample in Australia
  17. 2317
    “…At the beginning of 2012, psychiatrists with a specific interest in the rational use of psychotropic drugs were identified and appointed as members of a Guideline Development Group (GDG). …”
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    Making the use of psychotropic drugs more rational through the development of GRADE recommendations in specialist mental healthcare
  18. 2318
    por Bao, L., Wang, Y., Shang, T., Ren, X., Ma, R.
    Publicado 2013
    “…This system apparently improved work efficiency, standardized the level and accuracy of drug use, which will improve the rational drug use and pharmacy information service in our hospital. …”
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    A Novel Clinical Pharmacy Management System in Improving the Rational Drug Use in Department of General Surgery
  19. 2319
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    Rationally designed porous polystyrene encapsulated zirconium phosphate nanocomposite for highly efficient fluoride uptake in waters
  20. 2320
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    Rational syntheses of core-shell Fe(x)@Pt nanoparticles for the study of electrocatalytic oxygen reduction reaction
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