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  1. 2441
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    Rational Design of Antigen Incorporation Into Subunit Vaccine Biomaterials Can Enhance Antigen-Specific Immune Responses
  2. 2442
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    Rational Design of Amphiphilic Diblock Copolymer/MWCNT Surface Modifiers and Their Application for Direct Electrochemical Sensing of DNA
  3. 2443
    “…The proposed structural vaccinology method provides an avenue to rationally design the antigen’s structure with increased immunogenicity, which could be applied to the rational design of new COVID-19 vaccine candidates.…”
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    Rational Design of SARS-CoV-2 Spike Glycoproteins To Increase Immunogenicity By T Cell Epitope Engineering
  4. 2444
    “…Together with experimentally derived viral receptor identifications, we developed a structure-based in silico algorithm to inform a rational prediction for EV receptor usage.…”
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    Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage
  5. 2445
    por Rossell-Perry, Percy
    Publicado 2020
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    The Surgical Nasoalveolar Molding: A Rational Treatment for Unilateral Cleft Lip Nose Deformity and Literature Review
  6. 2446
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    Optogenetic activation of heterotrimeric G-proteins by LOV2GIVe, a rationally engineered modular protein
  7. 2447
    “…Herein, by combining in silico and in vitro screenings we initially identified 3-(cinnamylsulfanyl)-5-(4-pyridinyl)-1,2,4-triazol-4-amine (3) as α-syn aggregation inhibitor that was then considered a promising hit for the further design of a new series of small molecules. Therefore, we rationally designed new hit-derivatives that were synthesised and evaluated by biological assays. …”
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    Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson’s disease
  8. 2448
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    Rationally Attenuated Vaccines for Venezuelan Equine Encephalitis Protect Against Epidemic Strains with a Single Dose
  9. 2449
    “…This review focuses on the current status of research in peptides with dual antimicrobial–anticancer activity, including advances in computational biology using in silico analyses as a powerful tool for the study and rational design of these types of peptides.…”
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    Peptides with Dual Antimicrobial–Anticancer Activity: Strategies to Overcome Peptide Limitations and Rational Design of Anticancer Peptides
  10. 2450
    “…ADVANCES IN KNOWLEDGE: Proven methodology for rationalization of IVD measurements for TSEBT…”
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    Total skin electron beam therapy rationalization and utility of in vivo dosimetry in a high-volume centre
  11. 2451
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    Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes
  12. 2452
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    Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C
  13. 2453
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    Rational Design of Albumin Theranostic Conjugates for Gold Nanoparticles Anticancer Drugs: Where the Seed Meets the Soil?
  14. 2454
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    Rational strain engineering of single-atom ruthenium on nanoporous MoS(2) for highly efficient hydrogen evolution
  15. 2455
    “…Since the MED model is also computationally efficient, it can be used for reliable and rapid assessment of the ligand affinity or multidimensional scanning of amino acid side-chain conformations in the process of rational design of novel drugs or biocatalysts.…”
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    Extension of an Atom–Atom Dispersion Function to Halogen Bonds and Its Use for Rational Design of Drugs and Biocatalysts
  16. 2456
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    Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia
  17. 2457
    por Zou, Yuqin, Wang, Shuangyin
    Publicado 2021
    “…Active site identification in the CO(2)RR is vital for the understanding of the reaction mechanism and the rational development of new electrocatalysts with both high selectivity and stability. …”
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    An Investigation of Active Sites for electrochemical CO(2) Reduction Reactions: From In Situ Characterization to Rational Design
  18. 2458
    “…Here we exploited structure-based protein engineering to generate rationally modified fungal laccases with increased ability to process bulky PAHs even in a mediator-less reaction. …”
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    Rational engineering of the lccβ T. versicolor laccase for the mediator-less oxidation of large polycyclic aromatic hydrocarbons
  19. 2459
    “…The rations were formulated to be isonitrogenous. The animals were weighed at the start of the experiment and at days 30 and 60. …”
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    Nitrate supplementation of rations based on rice straw but not Pangola hay, improves growth performance in meat goats
  20. 2460
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    Rational design of a high-efficiency, multivariate metal–organic framework phosphor for white LED bulbs
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