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29801“…CONCLUSION: The aIAT is a variant of an attitude measure and can be better rationalized if propositional thinking is implied to explain outcomes. …”
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29802por Badurdeen, Shiraz, Valladares, David Benitez, Farrar, Jeremy, Gozzer, Ernesto, Kroeger, Axel, Kuswara, Novia, Ranzinger, Silvia Runge, Tinh, Hien Tran, Leite, Priscila, Mahendradhata, Yodi, Skewes, Ronald, Verrall, Ayesha“…BACKGROUND: The increasing frequency and intensity of dengue outbreaks in endemic and non-endemic countries requires a rational, evidence based response. To this end, we aimed to collate the experiences of a number of affected countries, identify strengths and limitations in dengue surveillance, outbreak preparedness, detection and response and contribute towards the development of a model contingency plan adaptable to country needs. …”
Publicado 2013
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29803por Knopf, Hildtraud, Wolf, Ingrid-Katharina, Sarganas, Giselle, Zhuang, Wanli, Rascher, Wolfgang, Neubert, Antje“…Clinical trials for licensing of paediatric medicines, education of health care professionals, but also of parents and carers are needed to ensure the rational use of medicines.…”
Publicado 2013
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29804“…We found that −77T>C polymorphism was associated with increased lung cancer risk (dominant model: odds ration [OR] = 1.45, 95% confidence interval [CI] = 1.27–1.66, recessive model: OR = 1.73, 95% CI = 1.14–2.62, additive model: OR = 1.91, 95% CI = 1.24–1.94) when all the eligible studies were pooled into the meta-analysis. …”
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29805“…Eight Holstein-Friesian cows were fed four diets during four successive17-day periods: 1) total mixed ration (TMR) containing 0% finely ground wheat (FGW) (W0); 2) TMR containing 10% FGW (W10); 3) TMR containing 20% FGW (W20); and 4) TMR containing 10% BP as a replacement for 10% ground corn (BP10). …”
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29806por Jesse, Helen E., Nye, Tacita L., McLean, Samantha, Green, Jeffrey, Mann, Brian E., Poole, Robert K.“…General significance: Rational design and exploitation of CO-RMs require a fundamental understanding of their activity. …”
Publicado 2013
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29807“…Much effort has been devoted to producing an accurate and rational annotation of the human genome. An annotated genome provides a comprehensive catalogue of genomic functional elements. …”
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29808por van Duuren, Jozef BJH, Puchałka, Jacek, Mars, Astrid E, Bücker, René, Eggink, Gerrit, Wittmann, Christoph, dos Santos, Vítor AP Martins“…BACKGROUND: Genome scale metabolic reconstructions are developed to efficiently engineer biocatalysts and bioprocesses based on a rational approach. However, in most reconstructions, due to the lack of appropriate measurements, experimentally determined growth parameters are simply taken from literature including other organisms, which reduces the usefulness and suitability of these models. …”
Publicado 2013
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29809“…Therefore, ample efforts are underway to rationally design therapies targeting the HCV non-structural proteins. …”
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29810por Anderegg, Angela, Lin, Hsin-Pin, Chen, Jun-An, Caronia-Brown, Giuliana, Cherepanova, Natalya, Yun, Beth, Joksimovic, Milan, Rock, Jason, Harfe, Brian D., Johnson, Randy, Awatramani, Rajeshwar“…Since canonical Wnt activity has recently been recognized as a key ingredient for programming ESCs towards a dopaminergic fate in vitro, these studies could impact the rational design of such protocols.…”
Publicado 2013
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29811por Yong, Kwon J, Milenic, Diane E, Baidoo, Kwamena E, Kim, Young-Seung, Brechbiel, Martin W“…Insight into these mechanisms could lead to improved strategies for rational application of radioimmunotherapy using α-particle emitters. …”
Publicado 2013
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29812por Mather, Richard C, Hug, Kevin T, Orlando, Lori A, Watters, Tyler Steven, Koenig, Lane, Nunley, Ryan M, Bolognesi, Michael P“…Other developed nations have used rationing and wait times to distribute this service. …”
Publicado 2014
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29813por Konarzewska, Beata, Stefańska, Ewa, Wendołowicz, Agnieszka, Cwalina, Urszula, Golonko, Anna, Małus, Aleksandra, Kowzan, Urszula, Szulc, Agata, Rudzki, Leszek, Ostrowska, Lucyna“…Body fat (kg), percent (%) body fat, fat-free mass, VAT (visceral adipose tissue) and SAT (subcutaneous adipose tissue) were measured using the bioelectrical impedance analysis (BIA) method. Daily food rations (DFR) were quantitatively evaluated by a 24-h dietary recall method covering 3 days preceding the examination. …”
Publicado 2014
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29814por Huang, Yang, Li, Zhenpeng, Xing, Hui, Jiao, Yang, Ouyang, Yabo, Liao, Lingjie, Jiang, Shibo, Armstrong, Rebecca, Shao, Yiming, Ma, Liying“…Monitoring these mutations will provide useful information for rational design of the NNRTI-based antiretroviral regimen for HIV-1 CRF_BC-infected patients.…”
Publicado 2014
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29815“…In order to check drug expenditures effectively in our current situation, in which chronic diseases remain steadily on the rise, it is necessary to not only have supply-side initiatives such as price reduction, but also demand-side initiatives that could control drug consumption volume, for example: educational programs for rational prescription, generic drug promotional policies, and policies providing prescription targets.…”
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29816“…However, the effectiveness of radiotherapy may be severely compromised by toxicities and tumor resistance due to radiation-induced adaptive response contributing to recurrence and metastases of breast cancer. The rational of using ZD6474 is to evaluate the feasibility and efficacy of combined VEGFR2 and EGFR targeting with concurrent targeted and localized UV-B phototherapy in vitro breast cancer cells with the anticipation to cure skin lesions infiltrated with breast cancer cells. …”
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29817por Doudican, Nicole A., Mazumder, Amitabha, Kapoor, Shweta, Sultana, Zeba, Kumar, Ansu, Talawdekar, Anay, Basu, Kabya, Agrawal, Ashish, Aggarwal, Aditi, Shetty, Krithika, Singh, Neeraj K, Kumar, Chandan, Tyagi, Anuj, Singh, Neeraj Kumar, Darlybai, Janitha C, Abbasi, Taher, Vali, Shireen“…Given that single agent therapy is a major clinical obstacle to overcome in the treatment of cancer, we sought to enhance the anti-cancer efficacy of UA through rational design of combinatorial therapeutic regimens that target multiple signaling pathways critical to carcinogenesis. …”
Publicado 2014
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29818“…Approaches such as strengthening performance evaluation, and carrying out initiatives to further mobilize frontline healthcare workers, enhance rational drug use through improved training and educate patients, should be undertaken in the future.…”
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29819“…Since K1A differs from E8 in the expression of Rgp, it is rational to conclude that Rgp contributes to immunomodulation in a more dynamic manner in comparison to Kgp. …”
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29820por Hill, Jenny, D'Mello-Guyett, Lauren, Hoyt, Jenna, van Eijk, Anna M., ter Kuile, Feiko O., Webster, Jayne“…METHODS AND FINDINGS: We searched the Malaria in Pregnancy Library, the Global Health Database, and the International Network for the Rational Use of Drugs Bibliography from 1 January 2006 to 3 April 2014, without language restriction. …”
Publicado 2014
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