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Racionalismo
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29921“…The most effective coping strategies the patients mentioned included: the rationalization of the symptoms, self-development and ignoring the symptoms. …”
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29922“…These structures transformed our understanding of the conformational changes induced by ATP binding and the mechanism of ligand specificity, and enabled homology modeling of mammalian P2X receptors for ligand docking and rational design of receptor modulators. P2X receptors are attractive drug targets, and a wide array of potent, subtype-selective modulators (mostly antagonists) have been developed. …”
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29923por King, Zoe M., Henshel, Diane S., Flora, Liberty, Cains, Mariana G., Hoffman, Blaine, Sample, Char“…The process must include characterizing the human factors that contribute to cyber security vulnerabilities and risk. Rationality, expertise, and maliciousness are key human characteristics influencing cyber risk within this context, yet maliciousness is poorly characterized in the literature. …”
Publicado 2018
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29924“…MATERIALS AND METHODS: Initially, the molecular docking analysis of AhR and cytochrome P450s (CYPs) (CYP1A1 and CYP1B1) was performed using MAESTRO tool, in an attempt to rationalize the activity of TAX, based on their CYP1-binding potential. …”
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29925“…The industry also rationalized manufacturing facilities and reduced the cost of tobacco, making Turkey a cigarette-manufacturing base. …”
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29926por Golder, Helen M., Thomson, Jennifer M., Denman, Stuart E., McSweeney, Chris S., Lean, Ian J.“…Initially, heifers (n = 40) allocated to five feed additive groups were fed 20-days pre-challenge with a total mixed ration and additives. Fructose (0.1% of bodyweight/day) was added for the last 10 days pre-challenge. …”
Publicado 2018
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29927por Gemmell, L.C., Webster, K.E., Kirtley, S., Vincent, K., Zondervan, K.T., Becker, C.M.“…Given the uncertain risks of initiating HRT, it is difficult to determine the best menopausal management for this group of women. OBJECTIVE AND RATIONAL: The aim of this study was to systematically review the existing literature on management of menopausal symptoms in women with a history of endometriosis. …”
Publicado 2017
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29928por Zhao, Jin, Liu, Yunxi, Liu, Yi, Wang, Dong, Ni, Wentao, Wang, Rui, Liu, Youning, Zhang, Bo“…The consistent resistance profile and common resistance genetic determinant highlight the importance of rational use of tigecycline for preventing the occurrence and spread of multidrug resistance.…”
Publicado 2018
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29929“…As a result of the study, it was seen that drug counseling services given by clinical pharmacists can effectively be employed in psychiatric care, for the rational use of medicines. It appears that it is necessary to take advantage of drug counseling on drug use and to develop strategies to improve drug compliance in psychiatry.…”
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29930“…Future pretreatment assessment of MET and AXL tumour aberration may aid clinicians to make a rational choice between currently approved second-line treatment options.…”
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29931por Coburn, Phillip S., Miller, Frederick C., LaGrow, Austin L., Parkunan, Salai Madhumathi, Blake Randall, C., Staats, Rachel L., Callegan, Michelle C.“…Because current therapeutics are often unsuccessful in mitigating damaging inflammation during endophthalmitis, more rational targets are needed. Toll-like receptors (TLRs) recognize specific motifs on invading pathogens and initiate the innate inflammatory response. …”
Publicado 2018
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29932“…Our findings could further provide new insights into the complexity of the regulation of ARF at the transcription level that may be useful to develop rational chickpea breeding strategies to improve development or stress responses. …”
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29933“…These results provide new insights into poxvirus immune evasion and have implications in the rational design of VACV-based therapeutics.…”
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29934por Pelleri, Maria Chiara, Cattani, Chiara, Vitale, Lorenza, Antonaros, Francesca, Strippoli, Pierluigi, Locatelli, Chiara, Cocchi, Guido, Piovesan, Allison, Caracausi, Maria“…The identification of genes contributing to DS pathogenesis could be the key to any rational therapy of the associated intellectual disability. …”
Publicado 2018
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29935“…Our findings may help to improve carbohydrate catabolic phenotype prediction and metabolic modeling, while it may also facilitate rational development of novel prebiotics.…”
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29936por Prudner, Bethany Cheree, Sun, Fangdi, Kremer, Jeffrey Charles, Xu, Jinbin, Huang, Chaofeng, Sai, Kiran Kumar Solingapuram, Morgan, Zachary, Leeds, Hayden, McConathy, Jonathan, Van Tine, Brian Andrew“…Rational: In a subset of cancers, arginine auxotrophy occurs due to the loss of expression of argininosuccinate synthetase 1 (ASS1). …”
Publicado 2018
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29937por Lv, Ya-Jie, Yang, Yi, Sui, Bing-Dong, Hu, Cheng-Hu, Zhao, Pan, Liao, Li, Chen, Ji, Zhang, Li-Qiang, Yang, Tong-Tao, Zhang, Shao-Feng, Jin, Yan“…Rational: Senescence of mesenchymal stem cells (MSCs) and the related functional decline of osteogenesis have emerged as the critical pathogenesis of osteoporosis in aging. …”
Publicado 2018
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29938“…Tumors ≥ 40 mm in size or with high-grade had significantly worse prognosis, which should be early diagnosed and treated with rational surgery.…”
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29939“…Lactating buffaloes were fed either a basal total mixed ration (TMR, control; 4 PP and 8 MP) or the basal TMR plus 10 g Yea-Sacc(1026) per buffalo cow per day (yeast; 4 PP and 8 MP). …”
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29940“…The objective of this study was to examine the effects of a fibrolytic enzyme product (Roxazyme G2 Liquid, 3.8 and 3.9 mL/kg total mixed ration [TMR] DM) supplemented to a TMR on production performance and blood parameters of dairy cows during early (trial 1) and mid-lactation (trail 2). …”
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