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30061“…CONCLUSION: RV-p scoring was able to provide a good predictive accuracy for 30-day mortality, which accounted for a more effective stratification of patients with RV-p into relevant risk categories and, consequently, help physicians to make more rational clinical decisions. The reviews of this paper are available via the supplemental material section.…”
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30062por Wu, Xiaofen, Ruan, Yao, Chen, Ting, Yu, Zonghe, Huo, Da, Li, Xiaomin, Wu, Feifei, Jiang, Xiao, Ren, Chunhua“…In summary, this current study has filled a knowledge gap on the biological function and expression profiles of an essential digestive enzyme in sea cucumber, which may encourage future investigation toward rationalized diets for H. leucospilota in artificial cultivation, and optimized heterogenous prokaryotic systems for producing recombinant enzymes of marine origins.…”
Publicado 2020
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30063por De Carolis, Martina, Barbato, Olimpia, Acuti, Gabriele, Trabalza-Marinucci, Massimo, Melo de Sousa, Noelita, Canali, Claudio, Moscati, Livia“…The goal is to diagnose pregnancy at early gestation in order to minimize the costs of unproductive animals and to properly formulate rations for the energy requirements of gestating or lactating animals at the same time. …”
Publicado 2020
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30064por Priatno, Wahyu, Jo, Yong-Ho, Nejad, Jalil Ghassemi, Lee, Jae-Sung, Moon, Jun-Ok, Lee, Hong-Gu“…Eight Hanwoo steers (initial BW = 424.6 kg [SD 42.3]; 477 days old [SD 4.8]) were randomly allocated to two groups (n = 4) of control and treatment and were supplied with total mixed ration (TMR). The treatment group was fed with 15 g of rumen-protected TRP (0.1% of TMR as-fed basis equal to 43.4 mg of TRP kg(−1) BW) once a day at 0800 h as top-dressed to TMR. …”
Publicado 2020
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30065por Clarkson, Kristen A., Frenck, Robert W., Dickey, Michelle, Suvarnapunya, Akamol E., Chandrasekaran, Lakshmi, Weerts, Hailey P., Heaney, Christopher D., McNeal, Monica, Detizio, Kate, Parker, Susan, Hoeper, Amy, Bourgeois, August L., Porter, Chad K., Venkatesan, Malabi M., Kaminski, Robert W.“…This study provides unique insights into the immune responses pre- and postinfection with S. sonnei 53G in a CHIM, which could help guide the rational design of future vaccines to induce protective immune responses more analogous to those triggered by infection. …”
Publicado 2020
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30066“…Suicide reflects many disparate determinants release/relief, response-to the disordered thinking, religious, revenge, rebirth, reunification or rational. 5-HT deficiency appears central to the neurobiology of suicide. …”
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30067por Jaroch, Tomasz, Maranda-Niedbała, Agnieszka, Krzyżewska, Klaudyna, Kotwica, Kamil, Bujak, Piotr, Skórka, Łukasz, Zagórska, Małgorzata, Proń, Adam, Nowakowski, Robert“…These differences are rationalized in terms of dissimilar molecular geometries of the studied isomers and different interdigitation patterns in their 2D supramolecular structures.…”
Publicado 2020
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30068por Bodkowski, Robert, Czyż, Katarzyna, Sokoła-Wysoczańska, Ewa, Janczak, Marzena, Cholewińska, Paulina, Wyrostek, Anna“…The supplementation of dairy cows’ rations with fish oil subjected to low-temperature crystallization (LTC-FO) enriched with long-chain polyunsaturated fatty acids reduced milk fat yield and concentration and profitably modified the fatty acid profile. …”
Publicado 2020
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30069por Dowdy, Tyrone, Zhang, Lumin, Celiku, Orieta, Movva, Sriya, Lita, Adrian, Ruiz-Rodado, Victor, Gilbert, Mark R., Larion, Mioara“…We exploited the pathway using a small-scale, rational drug screen and identified a combination that was lethal to IDH(mut) cells. …”
Publicado 2020
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30070por Tu, Mei-Juan, Duan, Zhijian, Liu, Zhenzhen, Zhang, Chao, Bold, Richard J., Gonzalez, Frank J., Kim, Edward J., Yu, Ai-Ming“…Consequently, miR-1291 effectively enhanced the efficacy of arginine deprivation (pegylated arginine deiminase) and chemotherapy (cisplatin), offering new insights into development of rational combination therapies.…”
Publicado 2020
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30071por Yamada, Hiroyuki, Chikamatsu, Kinuyo, Aono, Akio, Murata, Kazuyoshi, Miyazaki, Naoyuki, Kayama, Yoko, Bhatt, Apoorva, Fujiwara, Nagatoshi, Maeda, Shinji, Mitarai, Satoshi“…These fundamental morphological data strongly support the new classification in the family Mycobacteriaceae, and this classification is rational and effective in the study of the members of the family Mycobacteriaceae. …”
Publicado 2020
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30072por Maharaj, Kamira, Powers, John J., Mediavilla-Varela, Melanie, Achille, Alex, Gamal, Wael, Quayle, Steven, Jones, Simon S., Sahakian, Eva, Pinilla-Ibarz, Javier“…Based on the beneficial immunomodulatory activity of HDAC6 inhibition, we rationalized that HDAC6 inhibitors could enhance immune checkpoint blockade in CLL. …”
Publicado 2020
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30073por He, Hairong, Zhang, Jianfen, Zhang, Na, Du, Songming, Liu, Shufang, Ma, Guansheng“…Both the amount and frequency of fluid intake may affect urine osmolality and vigor, but these factors have limited impacts on cognitive performance. Rational fluid intake behavior may be beneficial to improve the hydration status and mood of young adults. …”
Publicado 2020
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30074“…Further studies are necessary to delineate the molecular function of EPHA2/E-cadherin signaling in radioresistant NPC and to explore rational combination therapy and its underlying mechanism.…”
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30075“…In contrast to the empirical optimization that predominated during the early years of molecular farming, the next generation of plant-made products are being produced by developing rational, tailor-made approaches to support their production. …”
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30076“…Great variations existed in antibiotic prescribing practices among physicians, indicating improvement potential for rational use of antibiotics. This study aims to identify antibiotic prescribing patterns of primary care physicians and potential determinants. …”
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30077por Chenlo, Miguel, Aliyev, Elvin, Rodrigues, Joana S., Vieiro-Balo, Paula, Blanco Freire, Manuel N., Cameselle-Teijeiro, José Manuel, Alvarez, Clara V.“…Moreover, we increased the quantitative dynamic range and resolution through increasing the signal/noise ration through reducing autofluorescence and increased longer antibody incubations. …”
Publicado 2020
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30078“…The cows were fed a basal total mixed ration diet with 0, 200, 350, and 500 g of RPG per cow per day, respectively. …”
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30079por Van Gool, Stefaan W., Makalowski, Jennifer, Fiore, Simon, Sprenger, Tobias, Prix, Lothar, Schirrmacher, Volker, Stuecker, Wilfried“…Individualized medicines, including multimodal immunotherapies, are a rational and optimal yet also flexible approach to induce long-term tumor control. …”
Publicado 2020
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30080por Jauralde, Ignacio, Velazco-Vargas, Jorge, Tomás-Vidal, Ana, Jover Cerdá, Miguel, Martínez-Llorens, Silvia“…Two trials for different weights of 53 and 188 g were conducted with rations from starvation to apparent satiation with the scope of studying its nutritional needs. …”
Publicado 2021
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