“…These results could provide a theoretical basis for the protection, rational exploitation and utilization of wild Morchella resources under scenarios of climate change.…”
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“…Manipulation of the microbiome is a rational treatment strategy for inflammatory bowel disease (IBD). …”
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“…Thus, it is suggested that repeated and sugar-free trickling treatments with moderate lithium dosage could be the most rational methodology. Since lithium is not yet legalised in beekeeping practice, comprehensive studies are also needed to uncover the amount of lithium residue in bee products, depending on the treatment parameters.…”
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“…Feeding fresh sugar beet (SB) to dairy cattle to replace a portion of the grain in the ration has not received sufficient attention. This study determined dry matter intake (DMI), feeding behavior, rumen fermentation and milk production responses when replacing corn grain with increasing levels of SB in pasture-fed lactating dairy cow diets. (2) Methods: A total of 12 early-lactation cows were used in a replicated (n = 4) 3 × 3 Latin square design. …”
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“…In-silico molecular docking studies, in combination with MD simulations and free energy, calculations were also performed to rationalize their time evolved mode of interaction inside the active pocket. …”
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“…OBJECTIVE: To investigate whether radiomics can help radiologists and thoracic surgeons accurately predict invasive adenocarcinoma (IAC) manifesting as part-solid nodules (PSNs) with solid components <6 mm and provide a basis for rational clinical decision-making. MATERIALS AND METHODS: In total, 1,210 patients (mean age ± standard deviation: 54.28 ± 11.38 years, 374 men and 836 women) from our hospital and another hospital with 1,248 PSNs pathologically diagnosed with adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), or IAC were enrolled in this study. …”
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“…Macrophage activation and failure to resolve play a role in ALI; thus, macrophage phenotype modulation is a rational target for therapeutic intervention. Large, lipid-laden macrophages have been observed in various injury models, including intratracheal bleomycin (ITB), suggesting that lipid storage may play a role in ALI severity. …”
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“…This study could provide suggestions for the rational allocation of vegetation in urban mountain parks in southeast coastal areas to improve local ecological service functions as habitats for urban wildlife, especially wild birds. …”
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“…Because of the heterogeneity of GBM, a multitarget drug is a rational strategy for GBM treatment. Histone deacetylase inhibitors (HDACis) regulate the expression of numerous genes involved in cell death, apoptosis, and tumorigenesis. …”
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“…Such treatment elicited no sign of in vivo toxicity and even exhibited remedial effects on the liver of tumor-bearing mice. ABSTRACT: Rational combinations of sequence-specific inhibitors of pro-oncogenic miRNAs can efficiently interfere with specific tumor survival pathways, offering great promise for targeted therapy of oncological diseases. …”
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“…KEY MESSAGES: Psychotropic medications are frequently prescribed for people with intellectual disabilities, often at high doses and these medications are associated with both positive and negative patient outcomes. Work to rationalize psychotropic use has been reported with interventions aiming to reduce polypharmacy or deprescribe a single psychotropic medicine. …”
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“…ABSTRACT: This research aims to develop a predictive model to discriminate milk produced from a cattle diet either based on grass or not using milk mid-infrared spectrometry and the month of testing (an indirect indicator of the feeding ration). The dataset contained 3,377,715 spectra collected between 2011 and 2021 from 2449 farms and 3 grazing traits defined following the month of testing. …”
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“…However, here we adopt an ecological rationality perspective, framing H/E-S functions as orchestrating SLAM processes within both concrete and abstract hypothesis spaces. …”
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“…From inactivation methodologies to reverse vaccinology, vaccine development strategies of 21st century have undergone several transformations and are moving towards rational design approaches. These developments are driven by data as the combinatorials involved in antigenic diversity of pathogens and immune repertoire of hosts are enormous. …”
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“…A review of criteria for reimbursement of insulin analogues by the National Health Insurance Fund is necessary in order to rationalize the expenses related to these molecules.…”
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“…To better understand the behavior of 3 under irradiation, a more comprehensive study, involving excitation of this compound in DMSO-d(6) followed by (1)H NMR, UV-Vis and fluorescence spectroscopy, was undertaken and further rationalized with the help of time-dependent density functional theory (TDDFT) electronic quantum calculations. …”
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“…In summary, the addition of appropriate levels of FGSM to rations improved broiler growth performance and reduced fat deposition by regulating gut microbes through differential metabolites and affecting the microbiota structure and SCFA content of the gut.…”
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“…The crystal violet assays indicated that the codY + ASyycF group formed less biofilms, which was consistent with the immunofluorescence results of the lowest live cell ration in the codY + ASyycF group. The expression levels of biofilm-associated icaA gene were significantly reduced in the codY + strain, indicating codY negatively regulates the biofilm formation. …”
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“…The application in the fields of industry, agriculture, environment, transportation, logistics, security and other infrastructure has effectively promoted the intelligent development of these aspects, which making the limited resources more rational use and distribution, thus improving the efficiency and benefit of the industry. …”
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