“…The findings suggest periodic awareness campaigns among practitioners regarding the implementation of the official guidelines, the need for systematic surveillance of AMR, awareness among pet owners about antimicrobial resistance, and the importance of rational use of antimicrobials on their pets.…”
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“…Thus, individual HMOs such as lacto-N-tetraose (LNT) and lacto-N-neotetraose (LNnT) are considered promising prebiotics that would stimulate the growth of bifidobacteria and confer multiple health benefits to preterm and malnourished children suffering from impaired (stunted) gut microbiota development. However, the rational selection of HMO-based prebiotics is hampered by the incomplete knowledge of regulatory mechanisms governing HMO utilization in target bifidobacteria. …”
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“…Our results expand the knowledge of bacterial inositol metabolism and provide an important basis for the rational development of producer strains for these valuable inositols, which show pharmacological activities against, e.g., Alzheimer’s disease, polycystic ovarian syndrome, or type II diabetes.…”
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“…However, the synergistic effect of randomly selected phages in the cocktails is ambiguous. Here, we rationally designed a phage cocktail consisting of four phages that utilize the lipopolysaccharide (LPS) O antigen, the LPS outer core, the LPS inner core, and the outer membrane proteins BtuB and TolC on the Salmonella enterica serovar Enteritidis cell surface as receptors. …”
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“…Thus, in this research, we report for the first time the rational design and synthesis of novel hybrid colloidal nanostructures composed of gold nanoparticles stabilized by trisodium citrate (AuNP@TSC) as the oxidase-like nanozyme, coupled with cobalt-doped superparamagnetic iron oxide nanoparticles stabilized by carboxymethylcellulose ligands (Co-MION@CMC) as the peroxidase-like nanozyme. …”
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“…It can also provide a practical path for clinical workers to help breast cancer families adjust rationally. CLINICAL TRIAL REGISTRATION: This study has been registered in the Chinese Clinical Trials Registry (Registration Number: http://www.chictr.org.cn/ChiCTR2100052108).…”
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“…Conclusions: Despite favorable perceptions, the fundamental understanding of physicians regarding ASPs and rational prescribing of antibiotics needs to be improved through context-specific educational interventions and capacity building. …”
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“…The overestimation of the k(overall) values by the kinetic studies using molecular modulation to generate CH(3)O(2) can be rationalized by a combination of underestimated optical absorbance of CH(3)O(2) and unaccounted CH(3)O(2) losses to the walls of the reaction cells employed.…”
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“…Six ruminally cannulated lactating Holstein dairy cows were adapted to a standard total mixed ration for 2 wk and sampled during the third week. …”
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“…Data from 30 lactating Holstein cows were assembled from 2 studies in which cows were milked by automated milking system (AMS) and fed a partial mixed ration (PMR) in feed bins that recorded intake behavior. …”
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“…In a practical genomic evaluation in US Holsteins, to get sufficient contributions from GEBV, 25K to 35K is a rational number of genotyped animals that can be randomly selected to compute SNP effects and obtain accurate and unbiased IGP. …”
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“…So that, glucose consumption may reflect oocyte matu- ration competence.…”
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“…Due to various experimental protocols, studies of this crucial question have been inconclusive, which hinders rational design of effective regulatory guidelines for safely handling NPs. …”
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“…Molecular analysis of therapy resistant tumors may provide the rational basis for new therapies (brivanib, CYC065, WEE1 kinase and other inhibitors). …”
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“…As well as modeling disease states, it is important to study the intestinal tract of guinea pigs to derive basic data for the rational use of guinea pig models. Therefore, we collected six different segments of the intestinal tissue of guinea pigs and analyzed the gene expression profiles and microbial composition of each of these regions. …”
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“…This dietary pattern affected FAP, which might achieve the ultimate goal of neuroprotection through the very long-chain SMs. A rational intake of dietary fatty acids might be an effective way on preventing MCI in the elderly.…”
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“…The significance of this study lies in ensuring safe/rational use of medicines and raising pharmacists’ working efficiency.…”
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“…The clinical application of this model allows early identification of the severity and prognosis for patients with SAP and GNB infection and identification of patients requiring urgent management thus allowing rationalization of treatment options and improvements in clinical outcomes.…”
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“…Crystallization is nontrivial, and learning about the zwitterion structures in solution is important for the rational improvement of the crystallization process. …”
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“…Combinatorial strategies designed to modulate macrophage polarization represent a rational approach to improve the anti-tumor activity of KD in GBM.…”
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