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  1. 30801
    “…Feedstuffs utilized in U.S. feedlot finishing rations incorporate high concentrations of N and P, with less than 15% of fed N and P retained by the animal. …”
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    Evaluation of the effects of wood-sourced biochar as a feedlot pen surface amendment on manure nutrient capture
  2. 30802
    “…Theoretically targeting human and viral receptors and enzymes via molecular docking and dynamics simulations can be considered a wise, rational, and efficient way to develop therapeutic agents against COVID-19. …”
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    In silico investigation of the therapeutic and prophylactic potential of medicinal substances bearing guanidine moieties against COVID-19
  3. 30803
    “…Therefore, RLPredictiOme provides a framework for genome-wide surveys of the RLP superfamily as a foundation to rationalize functional studies of surface receptors and their relationships with different biological processes.…”
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    RLPredictiOme, a Machine Learning-Derived Method for High-Throughput Prediction of Plant Receptor-like Proteins, Reveals Novel Classes of Transmembrane Receptors
  4. 30804
    “…During all periods, enrolled cows were fed the same base total mixed ration (TMR) ad libitum once daily. During P1 (7 d), baseline data were obtained for covariate analysis. …”
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    Effects of dietary microbial feed supplement on production efficacy in lactating dairy cows
  5. 30805
    “…Each filter bag contained 500 mg of ground total mixed ration (94.2% dry matter; 15.2% crude protein, 40.9% neutral detergent fiber, 3.9% fat, and 6.2% ash, dry matter basis) and three 5-mm glass beads. …”
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    Persistence of sugars used for intestinal permeability measures in an in vitro rumen environment
  6. 30806
    por Fehlberg, L.K., Pineda, A., Cardoso, F.C.
    Publicado 2021
    “…Cows consumed a total mixed ration with a DCAD of −118 mEq/kg for 4 wk prepartum and 397 mEq/kg for 4 wk postpartum. …”
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    Validation of 2 urine pH measuring techniques in a prepartum negative dietary cation-anion difference diet and the relationship with production performance
  7. 30807
    “…The therapy included routine recommendations for food consumption modification, motivational education in the School of Rational Eating, a steady diet, a low-calorie diet, aerobic physical exercises (running track), impulse physiotherapy on the rectus abdominis. …”
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    ODP389 Lipid Peroxidation System Reactivity in Adolescents During Constitutional Obesity Non-drug Therapy
  8. 30808
    “…Our critical analysis suggests a rational strategy for a tailored use of DS in male infertility. …”
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    PMON262 Systematic review and critical analysis on dietary supplements for male infertility: from a blend of ingredients to a rationale strategy
  9. 30809
    “…In WHR obesity, higher total VLDL particle concent36ration and remnant cholesterol, and lower HDL cholesterol were associated with an increased cardiovascular risk (P≤ 0.002). …”
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    Lipoprotein profiles of fat distribution and its association with insulin sensitivity
  10. 30810
    “…This research and future research in the field should help to determine rational public policies to help mitigate the risk of diseases and their impact on future pandemics.…”
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    Socioeconomic and Comorbid Factors Affecting Mortality and Length of Stay in COVID-19 Patients
  11. 30811
    “…Rational: Senescence is a major aging process that contributes to the development of cardiovascular diseases, but the underlying molecular mechanisms remain largely unknown. …”
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    circHIPK3 prevents cardiac senescence by acting as a scaffold to recruit ubiquitin ligase to degrade HuR
  12. 30812
    “…Regional cooperation for the prevention and control of TADs is necessary, but rational decisions should be made to initiate even sub-regional cooperation in the present geopolitical situation. …”
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    An Overview of Transboundary Animal Diseases of Viral Origin in South Asia: What Needs to Be Done?
  13. 30813
    por Cockrell, Chase, Larie, Dale, An, Gary
    Publicado 2022
    “…BACKGROUND: Preparation to address the critical gap in a future pandemic between non-pharmacological measures and the deployment of new drugs/vaccines requires addressing two factors: 1) finding virus/pathogen-agnostic pathophysiological targets to mitigate disease severity and 2) finding a more rational approach to repurposing existing drugs. It is increasingly recognized that acute viral disease severity is heavily driven by the immune response to the infection (“cytokine storm” or “cytokine release syndrome”). …”
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    Preparing for the next pandemic: Simulation-based deep reinforcement learning to discover and test multimodal control of systemic inflammation using repurposed immunomodulatory agents
  14. 30814
    “…The purpose of this study was to systematically evaluate the efficacy and safety of icotinib in the treatment of advanced EGFR mutation-positive NSCLC and to provide evidence-based evidence for clinical rational drug use. METHODS: Up to September 30, 2022, the databases of PubMed, EMBASE, Cochrane Library, ClinicalTrials.gov, China National Knowledge Infrastructure, and Wanfang were searched, and the randomized controlled trials (RCTs) of icotinib (experimental group) versus gefitinib or erlotinib (control group) in the treatment of EGFR-positive advanced NSCLC were included. …”
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    Efficacy and safety of icotinib in the treatment of advanced EGFR mutation-positive nonsmall cell lung cancer: A meta-analysis of randomized controlled trials
  15. 30815
    “…RATIONAL & OBJECTIVE: Many drugs, metabolites, and toxins are cleared by the kidneys via tubular secretion. …”
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    Estimated Kidney Tubular Secretion and Kidney, Cardiovascular, and Mortality Outcomes in CKD: The Systolic Blood Pressure Intervention Trial
  16. 30816
    “…Targeting the adrenomedullin system may provide a rational basis for future therapeutic modalities in melanoma. …”
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    Adrenomedullin Secreted by Melanoma Cells Promotes Melanoma Tumor Growth through Angiogenesis and Lymphangiogenesis
  17. 30817
    “…However, little is known about the rational composition of lysine and methionine in rabbit diets and the mechanisms that affect growth and development. …”
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    Effects of the SLC38A2–mTOR Pathway Involved in Regulating the Different Compositions of Dietary Essential Amino Acids–Lysine and Methionine on Growth and Muscle Quality in Rabbits
  18. 30818
    “…In this study, we use a large matched cohort study to estimate the risks of 12 serious diseases among patients presenting to primary care with UWL where this was recorded, stratified by age and sex, in order to inform a rational clinical approach to patients presenting with UWL. …”
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    Serious disease risk among patients with unexpected weight loss: a matched cohort of over 70 000 primary care presentations
  19. 30819
    “…Implementation of antimicrobial stewardship programs (AMS) have proven to be an effective tool for the rational use of antimicrobials, but their implementation has been a challenge in this region due to resources limitations. …”
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    904. Impact of a Pharmacist-driven Antimicrobial Stewardship Program on Prescribing Practices by Intensive Care Physicians in a Latin American Hospital.
  20. 30820
    “…We aimed to study the effectiveness of a pharmacist led AFS program to ensure rational prescribing of antifungals via a post-prescription review and feedback method. …”
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    1763. A study on the effectiveness of a pharmacist led Antifungal stewardship program, in immunocompromised patients of a tertiary care teaching hospital in South-India.
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