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  1. 30981
    “…Recent advances in computational tools, particularly the ones involving modern deep learning algorithms, have been shown to complement experimental approaches for describing and rationalizing PPIs. However, most of the existing works on PPI predictions use protein-sequence information, and thus have difficulties in accounting for the three-dimensional organization of the protein chains. …”
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    Struct2Graph: a graph attention network for structure based predictions of protein–protein interactions
  2. 30982
    “…Therefore, qualifying the antimicrobial dispensing process is a fundamental factor for improving the rational use of antimicrobials and reducing microbial resistance. …”
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    Antimicrobial dispensing process in community pharmacies: a scoping review
  3. 30983
    “…However, a considerable percentage of women were already at VTE-risk according to PATrisks and might have derived an additional benefit from LMWH in the form of VTE prevention. The rational use of these drugs should be optimized by establishing and implementing routine risk assessment for all pregnant women and by providing the necessary education to healthcare professionals.…”
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    Pregnancy and thrombosis risk for women without a history of thrombotic events: a retrospective study of the real risks
  4. 30984
    “…RESULTS: In the fully adjusted model, all-cause mortality was 1.97 times higher in the radiotherapy-only group (hazard ration (HR) = 1.97, 95% confidence interval (CI) = 1.81–2.14, p < 0.0001) than in the surgery-only group. …”
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    Surgery offers survival advantage over radiotherapy in patients who are 80 years and older with Stage I and II NSCLC: A retrospective cohort study of 7,045 patients
  5. 30985
    “…Despite the retrospective nature of this meta-analysis, these findings should help in designing relevant clinical trials rationally.…”
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    Efficacy of cetuximab plus PD-1 inhibitor differs by HPV status in head and neck squamous cell carcinoma: a systematic review and meta-analysis
  6. 30986
    “…INTRODUCTION: The aim of this study was to explore a method to rank the cost-effectiveness of presbyopia correction in diverse strategies of bilateral cataract surgery to provide references for healthcare policymakers in rationalizing resource utilization and surgeons in customizing patient management. …”
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    Cost-Effectiveness of Presbyopia Correction Among Seven Strategies of Bilateral Cataract Surgery Based on a Prospective Single-Blind Two-Center Trial in China
  7. 30987
    “…Rational irrigation and nitrogen management strategies are crucial for wheat growth. …”
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    A moderate reduction in irrigation and nitrogen improves water-nitrogen use efficiency, productivity, and profit under new type of drip irrigated spring wheat system
  8. 30988
    “…The research consisted of three steps: (1) Observing the similarity of the local nylon bag’s hole number to the imported bag. (2) Testing feed in situ degradation (F1 = Napier grass, F2 = Cornmeal, and F3 = Dairy cattle total mixed ration) using bags B1–B6. (3) The reusability of the bag was tested using different washing methods (under running water [R1], rinse [R2], and ultrasonic water bath [R3]). …”
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    In situ degradation of dairy cattle feedstuffs using reusable local nylon fabric bags
  9. 30989
    “…Although rhubarb has been widely used in Chinese medicine for the treatment of ulcerative colitis, the appropriate protocol is still demanded to its rational use in clinic, which promoted to evaluate the efficacy and safety for rhubarb-based therapy on ulcerative colitis. …”
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    The application of Tong-fu therapeutic method on ulcerative colitis: A systematic review and meta-analysis for efficacy and safety of rhubarb-based therapy
  10. 30990
    “…Our findings provide new ideas for rational use of fiber resources in weaned piglets. …”
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    Dietary fibers with low hydration properties exacerbate diarrhea and impair intestinal health and nutrient digestibility in weaned piglets
  11. 30991
    por Du, Wenwen, Liu, Ping, Xu, Wei
    Publicado 2022
    “…CONCLUSION: Decreasing the out-of-pocket expenses for outpatient care appropriately among people with diabetes could make patients have a more rational health-seeking behaviors, a better health status and a more reasonable medical expenses while the expenditure of the basic medical insurance funds is stable totally. …”
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    Effects of decreasing the out-of-pocket expenses for outpatient care on health-seeking behaviors, health outcomes and medical expenses of people with diabetes: evidence from China
  12. 30992
    “…It provides valuable guidance for health professionals to enable them to standardize practice and give rational advice to patients.…”
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    Suitability and Allocation of Protein-Containing Foods According to Protein Tolerance in PKU: A 2022 UK National Consensus
  13. 30993
    “…METHODS: An FE model of lumbar L1-S was established and referred to the previous in vitro experiments to verify the rationality of the model by verifying the Intradiscal pressure (IDP) and the range of motion (ROM) of the motion segment. …”
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    Biomechanical comparison of spinal column shortening - a finite element study
  14. 30994
    “…These studies may inform rational combination immuno-oncology (IO) strategies to be employed in the clinic on the backbone of standard of care, and in so doing exploit the immunogenic potential of standard of care to improve durable responses in HPV-associated malignancies. …”
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    Exploiting the immunogenic potential of standard of care radiation or cisplatin therapy in preclinical models of HPV-associated malignancies
  15. 30995
    “…There were 641 in development cohort and 275 in validation cohort (ration of 7:3). In the development cohort, a prediction model was developed based on the results of Logistic regression analysis. …”
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    Development and validation of short-term renal prognosis prediction model in diabetic patients with acute kidney injury
  16. 30996
    “…A total of 23 molecular candidates were successfully identified overall the 12 developmental stages and can be tested in many plant species to optimize SE protocols in a rational way. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12864-022-09098-z.…”
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    Global transcriptome profiling reveals differential regulatory, metabolic and hormonal networks during somatic embryogenesis in Coffea arabica
  17. 30997
    “…The TLPC model can non-invasively predict lymph node metastasis in NSCLC, which may be helpful for clinicians to develop more rational therapeutic strategies.…”
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    Developing a primary tumor and lymph node 18F-FDG PET/CT-clinical (TLPC) model to predict lymph node metastasis of resectable T2-4 NSCLC
  18. 30998
    “…CONCLUSION: By participating in the MTMs of outpatients, the pharmacists could identify more MRPs and develop personalized MAPs timely for patients, thereby promoting rational drug use and reducing medical expenses. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12913-023-09164-6.…”
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    The impact of pharmacist practice of medication therapy management in ambulatory care: an experience from a comprehensive Chinese hospital
  19. 30999
    “…This BM purification process is conducted at moderate temperatures in a KOH-based solution matrix. We rationally evaluate approaches to increase both the kinetic corrosion rate and the thermodynamic solubility of Al(0) and Cu(0), and evaluate the impact of these treatment conditions on the structure, chemistry, and electrochemical performance of NMC. …”
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    Optimized purification methods for metallic contaminant removal from directly recycled Li-ion battery cathodes
  20. 31000
    “…CONCLUSIONS: CTR, CLD, and MHD can predict the rationality of the parameters of the left breast cancer IMRT. …”
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    Individualized estimates of intensity-modulated radiotherapy plans after breast conservation surgery for left-sided breast cancer
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