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31401por Tian, Lei, Ai, Sinan, zheng, Huijuan, Yang, Hanwen, Zhou, Mengqi, Tang, Jingyi, Liu, Weijing, Zhao, Wenjing, Wang, Yaoxian“…The data for the outcomes were pooled and recorded as Hazard rations (HRs) with 95% confidence intervals (CLs). …”
Publicado 2022
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31402por Zhao, Hao, Liu, Chun-Hao, Cao, Yue, Zhang, Li-Yang, Zhao, Ya, Liu, Yue-Wu, Liu, Hong-Feng, Lin, Yan-Song, Li, Xiao-Yi“…Therefore, this systematic review and meta-analysis were performed to identify and summarize the prognostic factors in adult DTC patients with PM to help distinguish patients with different prognoses and inform the rational treatment regimens. METHOD: We performed a comprehensive search of the relevant studies published in the Cochrane Library, PubMed, Scopus, Embase, Wanfang database, VIP database, China National Knowledge Infrastructure, and Google Scholar from their inception until February 2021. …”
Publicado 2022
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31403por Kou, Ruxin, Mei, Kangni, Bi, Yuqing, Huang, Jingwen, Yang, Shilan, Chen, Kexuan, Li, Wei“…This study aims to assess the equity and trends of GP allocation in China from 2012 to 2021, summarize the efforts and progress of GPs in China during the decade, predict the development trend of GPs in mainland China in the next 5 years to provide a reference for regional health planning and rational allocation of GPs in China. METHODS: Data from 2012 to 2021 on GPs in 22 provinces, 5 autonomous regions, and 4 municipalities directly under the central government in mainland China (excluding Hong Kong, Macao, and Taiwan) are collected by us. …”
Publicado 2023
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31404por Wiesmüller, Gerhard A., Heinzow, Birger, Aurbach, Ute, Bergmann, Karl-Christian, Bufe, Albrecht, Buzina, Walter, Cornely, Oliver A., Engelhart, Steffen, Fischer, Guido, Gabrio, Thomas, Heinz, Werner, Herr, Caroline E. W., Kleine-Tebbe, Jörg, Klimek, Ludger, Köberle, Martin, Lichtnecker, Herbert, Lob-Corzilius, Thomas, Merget, Rolf, Mülleneisen, Norbert, Nowak, Dennis, Rabe, Uta, Raulf, Monika, Seidl, Hans Peter, Steiß, Jens-Oliver, Szewszyk, Regine, Thomas, Peter, Valtanen, Kerttu, Hurraß, Julia“…Risk groups to be protected particularly with regard to an infection risk are persons on immunosuppression according to the classification of the German Commission for Hospital Hygiene and Infection Prevention (Kommission für Krankenhaushygiene und Infektionsprävention, KRINKO) at the Robert Koch- Institute (RKI) and persons with cystic fibrosis (mucoviscidosis); with regard to an allergic risk, persons with cystic fibrosis (mucoviscidosis) and patients with bronchial asthma should be protected. The rational diagnostics include the medical history, physical examination, and conventional allergy diagnostics including provocation tests if necessary; sometimes cellular test systems are indicated. …”
Publicado 2017
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31405por Göpel, Siri, Bethge, Wolfgang, Martus, Peter, Kreth, Florian, Iftner, Thomas, Joos, Stefanie, Döbele, Stefanie, Mordmüller, Benjamin, Kremsner, Peter, Ettrich, Thomas, Seufferlein, Thomas, Bitzer, Michael, Malek, Nisar“…NUMBERS TO BE RANDOMISED (SAMPLE SIZE): In the first stage of an adaptive design 120 patients in a 2:1 ration: 72 Verum and 36 Placebo, plus an increase for 10% drop outs. …”
Publicado 2020
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31406por Bashir, Salam, Fezeu, Leopold K., Leviatan Ben-Arye, Shani, Yehuda, Sharon, Reuven, Eliran Moshe, Szabo de Edelenyi, Fabien, Fellah-Hebia, Imen, Le Tourneau, Thierry, Imbert-Marcille, Berthe Marie, Drouet, Emmanuel B., Touvier, Mathilde, Roussel, Jean-Christian, Yu, Hai, Chen, Xi, Hercberg, Serge, Cozzi, Emanuele, Soulillou, Jean-Paul, Galan, Pilar, Padler-Karavani, Vered“…CONCLUSIONS: We found a clear link between the levels and repertoire of serum anti-Neu5Gc IgG and Neu5Gc intake from red meat and dairy. These precise rational methodologies allowed to develop a Gcemic index to simplify the assessment of Neu5Gc in foods that could potentially be adapted for dietary recommendations to reduce cancer risk.…”
Publicado 2020
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31407“…It is crucial to assess the ADR status in African Plasmodium falciparum isolates from imported malaria cases, as this will provide valuable information for rational medication and malaria control. METHODS: During 2017–2019, a cross-sectional study was carried out in Wuhan, China. …”
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31408“…The methods of key informants interview, snowball sampling, and rational sampling were all used in field investigations. …”
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31409por Rosa, Bruno, Margalit-Yehuda, Reuma, Gatt, Kelly, Sciberras, Martina, Girelli, Carlo, Saurin, Jean-Christophe, Cortegoso Valdivia, Pablo, Cotter, Jose, Eliakim, Rami, Caprioli, Flavio, Baatrup, Gunnar, Keuchel, Martin, Ellul, Pierre, Toth, Ervin, Koulaouzidis, Anastasios“…This review presents a comprehensive account of the currently available classification/scoring systems in clinical CE spanning from predicting the bleeding potential of identified SB lesions (with emphasis on vascular lesions), and the individual rebleeding risk; scoring systems for the prediction of SB lesions in patients with obscure gastrointestinal bleeding (OGlB), having the potential to improve patient selection and rationalize the use of enteroscopy, with better allocation of resources, optimized diagnostic workflow and tailored treatment. …”
Publicado 2021
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31410por Kamvura, Tiny Tinashe, Turner, Jean, Chiriseri, Ephraim, Dambi, Jermaine, Verhey, Ruth, Chibanda, Dixon“…Although task-shifting appears to be a rational approach, evidence suggests that it may bring about tension between existing professionals from whom tasks are shifted. …”
Publicado 2021
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31411por Makkouk, Amani, Yang, Xue (Cher), Barca, Taylor, Lucas, Anthony, Turkoz, Mustafa, Wong, Jonathan T S, Nishimoto, Kevin P, Brodey, Mary M, Tabrizizad, Maryam, Gundurao, Smitha R Y, Bai, Lu, Bhat, Arun, An, Zili, Abbot, Stewart, Satpayev, Daulet, Aftab, Blake T, Herrman, Marissa“…BACKGROUND: Glypican-3 (GPC-3) is an oncofetal protein that is highly expressed in various solid tumors, but rarely expressed in healthy adult tissues and represents a rational target of particular relevance in hepatocellular carcinoma (HCC). …”
Publicado 2021
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31412por Liu, Chunhui, Wang, Yanjie, Ma, Xiaoding, Cui, Di, Han, Bing, Xue, Dayuan, Han, Longzhi“…The traditional agricultural management of Dong people provides suitable habitats for flora and fauna with biodiversity protection, and convenient conditions for rational utilization and distribution of water resources were also provided. …”
Publicado 2022
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31413por Lattanzi, Simona, Canafoglia, Laura, Canevini, Maria Paola, Casciato, Sara, Cerulli Irelli, Emanuele, Chiesa, Valentina, Dainese, Filippo, De Maria, Giovanni, Didato, Giuseppe, Falcicchio, Giovanni, Fanella, Martina, Ferlazzo, Edoardo, Gangitano, Massimo, Giorgi, Filippo Sean, La Neve, Angela, Mecarelli, Oriano, Montalenti, Elisa, Morano, Alessandra, Piazza, Federico, Pulitano, Patrizia, Quarato, Pier Paolo, Ranzato, Federica, Rosati, Eleonora, Tassi, Laura, Di Bonaventura, Carlo“…Real-world studies can therefore be a useful complement to characterize the drug’s profile. Brivaracetam is a rationally developed compound characterized by high-affinity binding to synaptic vesicle protein 2A and approved as adjunctive therapy for focal seizures in adults with epilepsy. …”
Publicado 2022
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31414“…This study warrants a holistic vector control approach for all medically important mosquitoes and insects, ensuring the rational use of finance and resources. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13071-022-05261-3.…”
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31415por Du, Ruofei, Yang, Huashan, Zhou, Huiyue, Ma, Lixia, Getu, Mikiyas Amare, Chen, Changying, Wang, Tao“…BACKGROUND: High medication literacy is the basis of rational medication application and is essential for the management of severe adverse drug reactions. …”
Publicado 2022
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31416por Pimentel, Raquel, Leitão, Jorge, Gregório, Carlos, Santos, Lélita, Carvalho, Armando, Figueiredo, Pedro“…The emergence of bacteria resistant to traditionally recommended empirical antibiotics underlines the importance of basing this choice on local flora and antibiotic susceptibility data, allowing a more rational and successful use of antibiotics.…”
Publicado 2021
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31417por Itson-Zoske, Brandon, Shin, Seung Min, Xu, Hao, Qiu, Chensheng, Fan, Fan, Hogan, Quinn H., Yu, Hongwei“…Here, we test the hypothesis that the T-type/Ca(V)3.2 channels in PSNs can be rationally targeted for pain relief in MIA-OA. METHODS: MIA model of knee OA was induced in male and female rats by a single injection of 2 mg MIA into intra-knee articular cavity. …”
Publicado 2022
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31418por Liu, Dan, Zhou, Jun, Wang, Yongsheng, Li, Mingjun, Jiang, Haiping, Liu, Yunpeng, Yin, Xianli, Ge, Minghua, Xiang, Xiaojun, Ying, Jieer, Huang, Jian, Zhang, Yan-qiao, Cheng, Ying, Huang, Zhigang, Yuan, Xianglin, Han, Weiqing, Yan, Dong, Wang, Xinshuai, Liu, Pan, Wang, Linna, Zhang, Xiaojing, Luo, Suxia, Liu, Tianshu, Shen, Lin“…BACKGROUND: Dual inhibition of PD-1/PD-L1 and TGF-β pathways is a rational therapeutic strategy for malignancies. SHR-1701 is a new bifunctional fusion protein composed of a monoclonal antibody against PD-L1 fused with the extracellular domain of TGF-β receptor II. …”
Publicado 2022
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31419“…Then the 2 risk scoring models were constructed based on the same method of calculation whose samples were acquired from the CGGA dataset and TCGA datasets to verify the rationality and the reliability of the risk scoring model. …”
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31420“…As an attempt to lay a scientific basis for guiding the rational intake of dairy by Chinese residents, we launched a survey to discover Chinese residents’ knowledge about dairy product, intake and purchasing behavior of dairy and its influencing factors. …”
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