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Mostrando 421 - 440 Resultados de 31,513 Para Buscar '"rationalism"', tiempo de consulta: 2.62s Limitar resultados
  1. 421
    “…This information allowed a rational approach to novel drug design. Our team approach with schistosome biologists, medicinal chemists, structural biologists and geneticists has enabled us to develop and test novel drug derivatives of OXA to treat this disease. …”
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    Rational approach to drug discovery for human schistosomiasis
  2. 422
    “…By its very nature, this Opinion is partly subjective and we do not attempt to provide a comprehensive guide to the best practices of CADD; instead, we wish to stimulate an open discussion within the scientific community and advocate rational rather than fashion-driven use of computational methods. …”
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    Rationality over fashion and hype in drug design
  3. 423
    por Dotlačil, Jakub, de Haan, Puck
    Publicado 2021
    “…This paper explores how the rational theory of memory summarized in Anderson (1991) can inform the computational psycholinguistic models of human parsing. …”
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    Parsing Model and a Rational Theory of Memory
  4. 424
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    Fixed-dose combinations: An essential for rational preparation
  5. 425
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    Algorithm of rational approach to reconstruction in Fournier’s disease
  6. 426
    por Field, Claire
    Publicado 2020
    “…I argue for the unexceptionality of evidence about what rationality requires. Specifically, I argue that, as for other topics, one’s total evidence can sometimes support false beliefs about this. …”
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    Anti-Exceptionalism About Requirements of Epistemic Rationality
  7. 427
    por Reinagel, Pamela
    Publicado 2021
    “…The neural mechanisms underlying such “rational” market behaviors remain largely unexplored. …”
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    Rational regulation of water-seeking effort in rodents
  8. 428
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    Protein engineering strategies for rational immunogen design
  9. 429
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    MRI-Linac Economics II: Rationalizing Schedules
  10. 430
    “…Rational decision makers aim to maximize their gains, but humans and other animals often fail to do so, exhibiting biases and distortions in their choice behavior. …”
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    Apparent sunk cost effect in rational agents
  11. 431
    “…The literatures on bounded and ecological rationality are built on adaptationism—and its associated modular, cognitivist and computational paradigm—that does not address or explain the evolutionary origins of rationality. …”
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    More Thumbs Than Rules: Is Rationality an Exaptation?
  12. 432
    “…BACKGROUND: It is impossible to meet all healthcare demands, but an open and fair rationing process may improve the public acceptability of priority setting in healthcare. …”
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    Public participation: healthcare rationing in the newspaper media
  13. 433
    por Felin, Teppo, Koenderink, Jan
    Publicado 2022
    “…In this paper we contrast bounded and ecological rationality with a proposed alternative, generative rationality. …”
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    A Generative View of Rationality and Growing Awareness(†)
  14. 434
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    Rational inference strategies and the genesis of polarization and extremism
  15. 435
    “…It also provides some clues and elements of thoughts for a rational approach of complement modulation in kidney diseases.…”
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    The Rational Use of Complement Inhibitors in Kidney Diseases
  16. 436
    “…[Image: see text] Metal–organic polyhedra (MOPs) are hybrid organic–inorganic nanomolecules, whose rational design depends on harmonious consideration of chemical complementarity and spatial compatibility between two or more types of chemical building units (CBUs). …”
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    Automated Rational Design of Metal–Organic Polyhedra
  17. 437
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    Mechanistic insights into the rational design of masked antibodies
  18. 438
    “…One aspect of adaptive expertise with rational numbers is adaptive rational number knowledge, which refers to the ability to integrate knowledge of numerical characteristics and relations in solving novel tasks. …”
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    Predicting adaptive expertise with rational number arithmetic
  19. 439
    “…Here, state-of-the-art knowledge of microscopic colitis is provided from a global perspective with reference to etiopathology and how to establish the diagnosis with the overall aim to create awareness and improve rational management in clinical practice. The immune system and a dysregulated immune response seem to play a key role combined with risk factors (e.g. cigarette smoking) in genetically predisposed individuals. …”
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    Microscopic colitis: Etiopathology, diagnosis, and rational management
  20. 440
    “…For each PROTAC such linker parameters as chemical nature, length, hydrophilicity and rigidity have to be optimized to achieve improved stability, bioavailability cell membrane permeability and suitable spatial orientation between the target POI and the E3 ubiquitin ligase. Thus rational linker design with respect to composition, length and attachment sites is essential for the development of potent PROTAC compounds. …”
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    Novel approaches for the rational design of PROTAC linkers
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