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  1. 1001
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    Promoter knock-in: a novel rational method for the fine tuning of genes
  2. 1002
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    Rational design of HIV vaccine and microbicides: report of the EUROPRISE annual conference
  3. 1003
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    NEUROLOGICAL SOFT SIGNS, COGNITIVE DYSFUNCTION AND VENTRICULAR BRAIN RATION IN SCHIZOPHRENICS
  4. 1004
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    Connecting Peptide Physicochemical and Antimicrobial Properties by a Rational Prediction Model
  5. 1005
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    Rational Design of Temperature-Sensitive Alleles Using Computational Structure Prediction
  6. 1006
    “…While rational design of protein–protein interaction inhibitors is at its very early stage, the first results are promising.…”
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    Computer applications for prediction of protein–protein interactions and rational drug design
  7. 1007
    “…Importantly, this initial Ala scan suggested a specific interaction of the region around R11 with the CaMKII substrate binding site, which was exploited for further rational mutagenesis to generate an optimized pseudo-substrate sequence. …”
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    Improving a Natural CaMKII Inhibitor by Random and Rational Design
  8. 1008
    “…We address two aspects of general interest for the chemical synthesis of colloidal semiconductor nanocrystals: (1) the rational design of the synthesis protocol aiming at the optimization of the reaction parameters in a minimum number of experiments; (2) the transfer of the procedure to the gram scale, while maintaining a low size distribution and maximizing the reaction yield. …”
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    Rational design of the gram-scale synthesis of nearly monodisperse semiconductor nanocrystals
  9. 1009
    por Samama, Charles Marc, Godier, Anne
    Publicado 2011
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    Drotrecogin alpha: a rational approach to the treatment of submassive pulmonary embolism?
  10. 1010
    “…The notion of ecological rationality sees human rationality as the result of the adaptive fit between the human mind and the environment. …”
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    Ecological Rationality: A Framework for Understanding and Aiding the Aging Decision Maker
  11. 1011
    por Doberstein, S, Lazar, G, Hayes, R
    Publicado 2003
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    Rational engineering of Fc/Fc receptor interactions to improve antibody potency
  12. 1012
    por Kim, Won Seog
    Publicado 2012
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    Utilizing CD30 expression as a rational target for therapy of lymphoma
  13. 1013
    por Ibrahim, Hiba, Barrow, Paul, Foster, Neil
    Publicado 2011
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    Transcriptional modulation by VIP: a rational target against inflammatory disease
  14. 1014
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    Rational Mutagenesis of Cyclodextrin Glucanotransferase at the Calcium Binding Regions for Enhancement of Thermostability
  15. 1015
    “…We expect that our method will aid the rational design of enzyme allosteric regulation strategies and facilitate the control of metabolic flux.…”
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    Rational Engineering of Enzyme Allosteric Regulation through Sequence Evolution Analysis
  16. 1016
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    Rational immunogen design to target specific germline B cell receptors
  17. 1017
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    Rational engineering of sequence specificity in R.MwoI restriction endonuclease
  18. 1018
    “…Further strengthening of, and adherence to, guidelines is needed to ensure rational use of FQs.…”
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    Protecting the tuberculosis drug pipeline: stating the case for the rational use of fluoroquinolones
  19. 1019
    “…We present an approach for rational design and optimization of plasmonic arrays for ultrasensitive surface enhanced infrared absorption (SEIRA) spectroscopy of specific protein analytes. …”
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    Rational design and optimization of plasmonic nanoarrays for surface enhanced infrared spectroscopy
  20. 1020
    “…The objectives of this study were 1) develop and implement a discipline based on the WHO’s Guide to Good Prescribing; 2) evaluate the course acceptance by students; 3) assess the impact that the Rational Use of Medicines (RUM) knowledge had on the students habits of prescribing medication in the University Hospital. …”
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    Teaching the Rational Use of Medicines to medical students: a qualitative research
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