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  1. 1021
    por Magowska, Anita
    Publicado 2012
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    Wandering Spleen: A Medical Enigma, Its Natural History and Rationalization
  2. 1022
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    Semi-rational engineering of cellobiose dehydrogenase for improved hydrogen peroxide production
  3. 1023
    por Chok, Jay, Qian, Jifeng
    Publicado 2013
    “…In this study, we examine how initial public offerings (IPO) entry rates are affected when stock markets are boundedly rational and IPO firms infer information from their counterparts in the market. …”
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    Comparable Stocks, Boundedly Rational Stock Markets and IPO Entry Rates
  4. 1024
    “…These data provide a comparison of sorafenib with supportive care and demonstrate the potential detrimental impact on patient outcomes of rationing health-care resources on the basis of cost.…”
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    Sorafenib for advanced hepatocellular carcinoma (HCC): impact of rationing in the United Kingdom
  5. 1025
    “…Several studies have been performed about rational use of drugs in Iran. OBJECTIVE: The objective of this study was to assess scientific output on rational use of drugs in Iran using a bibliometric analysis of publications. …”
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    A bibliometric study of publication patterns in rational use of medicines in Iran
  6. 1026
    “…These producers, and the corresponding peptides, exhibited enhanced bioactivity against Lactococcus lactis HP, Streptococcus agalactiae ATCC 13813, Mycobacterium smegmatis MC2155 and Staphylococcus aureus RF122 and thus represent the first example of nisin derivatives that possess enhanced activity as a consequence of rational design.…”
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    Intensive Mutagenesis of the Nisin Hinge Leads to the Rational Design of Enhanced Derivatives
  7. 1027
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    Rational Design of a Triple Reporter Gene for Multimodality Molecular Imaging
  8. 1028
    por Dawson, John C., Carragher, Neil O.
    Publicado 2014
    “…We further describe how the incorporation of high-throughput reverse phase protein microarrays with phenotypic screening can provide rational drug combination hypotheses but also confirm the mechanism-of-action of novel drug combinations, to facilitate future preclinical and clinical development strategies.…”
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    Quantitative phenotypic and pathway profiling guides rational drug combination strategies
  9. 1029
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    Rational design and validation of a Tip60 histone acetyltransferase inhibitor
  10. 1030
    “…Our web server, TSpred (http://mspc.bii.a-star.edu.sg/TSpred/), now enables users to rationally design Ts mutants for their proteins of interest. …”
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    TSpred: a web server for the rational design of temperature-sensitive mutants
  11. 1031
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    Rationalization of allosteric pathway in Thermus sp. GH5 methylglyoxal synthase
  12. 1032
    “…We report the results of a simulation study in which we explore the joint effect of group absorptive capacity (as the average individual rationality of the group members) and cognitive distance (as the distance between the most rational group member and the rest of the group) on the emergence of collective rationality in groups. …”
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    Cognitive Distance, Absorptive Capacity and Group Rationality: A Simulation Study
  13. 1033
    “…Here, we report the rational design of structure-switching DNA aptamers, based on the thrombin binding aptamer (TBA), that bind potassium with affinities that bridge the gap between previously reported weak-binding and strong-binding aptamers. …”
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    Rational design of a structure-switching DNA aptamer for potassium ions
  14. 1034
    por Briggs, Andrew
    Publicado 2014
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    Rational allocation of resources available for healthcare: understanding cost effectiveness analyst
  15. 1035
    “…Our results contribute to the optimization of gag inhibitors in rational drug design, given that drug binding sites should ideally be conserved across all HIV-1 subtypes.…”
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    Functional conservation of HIV-1 Gag: implications for rational drug design
  16. 1036
    por Barroga, Edward F.
    Publicado 2014
    “…It is often beset with flaws as well as accusations of unreliability and lack of predictive validity. 'Rational cheating' by reviewers is a threat to the validity of peer review. …”
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    Safeguarding the Integrity of Science Communication by Restraining 'Rational Cheating' in Peer Review
  17. 1037
    por Sen, Dwaipayan
    Publicado 2014
    “…This article reviews the various aspects of rationally designing AAV capsids like by site-directed mutagenesis, directed evolution and combinatorial libraries which can create vectors having not only immune evasive property but also enhanced gene expression and transduction capability. …”
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    Improving clinical efficacy of adeno associated vectors by rational capsid bioengineering
  18. 1038
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    Rationally Designed Peptidomimetic Modulators of Aβ Toxicity in Alzheimer's Disease
  19. 1039
    “…While treating diarrhea, 7.20%, 17.80% and 20.08% respectively advised antibiotics, IVF and laboratory tests rationally. Logistic regression revealed that qualified and Governmental-sector practitioners managed diarrhea more rationally. …”
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    Predictors of Rational Management of Diarrhea in an Endemic Setting: Observation from India
  20. 1040
    por Mandel, David R.
    Publicado 2015
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    Communicating numeric quantities in context: implications for decision science and rationality claims
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