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  1. 1821
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    An Open Question: Is It Rational to Inhibit the mTor-Dependent Pathway as COVID-19 Therapy?
  2. 1822
    por Xu, Fuming, Xiang, Peng, Huang, Long
    Publicado 2020
    “…Despite some debate, the SMH has provided not only a neurobiological framework for understanding emotion and decision-making but also a good empirical support for ecological rationality and embodied emotion. Unlike the traditional maximizing rationality and bounded satisficing rationality, the ecological rationality stresses that emotions should be brought to the decision-making process. …”
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    Bridging Ecological Rationality, Embodied Emotion, and Neuroeconomics: Insights From the Somatic Marker Hypothesis
  3. 1823
    “…While there have been many efforts to develop computational tools to guide rational antibody engineering, most approaches are of limited accuracy when applied to antibody design, and have largely been limited to analysing a single point mutation at a time. …”
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    mmCSM-AB: guiding rational antibody engineering through multiple point mutations
  4. 1824
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    Reverse genetic systems: Rational design of coronavirus live attenuated vaccines with immune sequelae
  5. 1825
    “…The dominant political rationality used to frame NCDs is rooted in risk governmentality. …”
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    Governing Noncommunicable Diseases Through Political Rationality and Technologies of Government: A Discourse Analysis
  6. 1826
    por Wilken, Lucas, Rimmelzwaan, Guus F.
    Publicado 2020
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    Adaptive Immunity to Dengue Virus: Slippery Slope or Solid Ground for Rational Vaccine Design?
  7. 1827
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    Prefrontal cortical alterations of glutamate and GABA neurotransmission in schizophrenia: Insights for rational biomarker development
  8. 1828
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    Intercepting second-messenger signaling by rationally designed peptides sequestering c-di-GMP
  9. 1829
    “…The rational-based neuro-transfer function (neuro-TF) method is a popular method for parametric modeling of electromagnetic (EM) behavior of microwave components. …”
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    Novel Decomposition Technique on Rational-Based Neuro-Transfer Function for Modeling of Microwave Components
  10. 1830
    “…Even more difficult is the design of protein-based bulk materials without any functional starting scaffold for further optimization. Here, we show the rational design of proton-conducting, protein materials exceeding reported proteinaceous systems. …”
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    De novo rational design of a freestanding, supercharged polypeptide, proton-conducting membrane
  11. 1831
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    COVID-19 Patients with Pulmonary Fibrotic Tissue: Clinical Pharmacological Rational of Antifibrotic Therapy
  12. 1832
    por Tang, Fang, Zhan, Peida
    Publicado 2020
    “…This study developed an instrument for longitudinal learning diagnosis of rational number operations. In order to provide a reference for practitioners to develop the instrument for longitudinal learning diagnosis, the development process was presented step by step. …”
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    The Development of an Instrument for Longitudinal Learning Diagnosis of Rational Number Operations Based on Parallel Tests
  13. 1833
    “…Detailed understanding of antibiotic mechanisms can address this issue by facilitating the rational design of improved combination therapies. …”
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    Mechanistic Understanding Enables the Rational Design of Salicylanilide Combination Therapies for Gram-Negative Infections
  14. 1834
    por Rockwood, Kenneth
    Publicado 2020
    “…The COVID-19 pandemic has seen a proposal for frailty to be used as a rationing criterion. This commentary suggests circumstances under which that is defensible: in the face of lack of capacity to treat everyone, and as an alternative to age in stratifying risk. …”
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    Rationing care in COVID-19: if we must do it, can we do better?
  15. 1835
    “…Protein engineering enables rational alteration of substrate preference, providing a future blue print for the application of this and related enzymes in bioremediation.…”
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    Catabolic Reductive Dehalogenase Substrate Complex Structures Underpin Rational Repurposing of Substrate Scope
  16. 1836
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    Rational Drug Design and Docking of the RNA Dependent RNA Polymerase Domain of NCoV
  17. 1837
    “…Using the example of New Jersey’s Crisis Standard of Care policy, we describe how dominant rationing guidance compounds for many Black patients prior unfair structural disadvantage, chiefly due to the way creatinine and life expectancy are typically considered. …”
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    Rationing, racism and justice: advancing the debate around ‘colourblind’ COVID-19 ventilator allocation
  18. 1838
    “…This model helps to develop new synthesis strategies for rational design of the highly selective imprinted polymers and to use as a sensing platform for water soluble and polar targets.…”
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    Rational Design of Molecularly Imprinted Polymers Using Quaternary Ammonium Cations for Glyphosate Detection
  19. 1839
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    Room to Breathe: The Impact of Oxygen Rationing on Health Outcomes in SARS-CoV2
  20. 1840
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    Experimental and theoretical explorations of nanocarriers’ multistep delivery performance for rational design and anticancer prediction
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