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118301por Tavaglione, Federica, Baselli, Guido, Ciociola, Ester, Gentilucci, Umberto Vespasiani, Valenti, Luca, Romeo, Stefano“…Despite the high prevalence of NAFLD, only a minority of patients progress to NASH and advanced fibrosis. The reasons for this inter-individual variability are not completely understood but can be partially accounted for by genetic risk factors (1). …”
Publicado 2020
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118302por Abraham, Olufunmilola, LeMay, Sarah, Bittner, Sarah, Thakur, Tanvee, Stafford, Haley, Brown, Randall“…Theoretical frameworks identified in the 12 serious games included information, motivation, and behavior theory; social cognitive theory; precede-proceed model; middle-range theory of chronic illness; adult learning theory; experiential learning theory; and the theory of reasoned action. Existing reviews explore serious games focused on the management of specific disease states, such as HIV, diabetes, and asthma, and on the positive impact of serious game education in each respective disease state. …”
Publicado 2020
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118303por El Shafie, Rami A., Tonndorf-Martini, Eric, Schmitt, Daniela, Celik, Aylin, Weber, Dorothea, Lang, Kristin, König, Laila, Höne, Simon, Forster, Tobias, von Nettelbladt, Bastian, Adeberg, Sebastian, Debus, Jürgen, Rieken, Stefan, Bernhardt, Denise“…SI-VMAT could be a reasonable alternative to a dedicated radiosurgery system for selected patients with multiple BM.…”
Publicado 2020
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118304por Roebroek, Lukas, Bruins, Jojanneke, Knegtering, Henderikus, Delespaul, Philippe, Boonstra, Albert, Castelein, Stynke“…This in turn influenced their clinical reasoning and in some cases their clinical decisions. …”
Publicado 2020
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118305por Bañó, Maria, Morén, Constanza, Barroso, Sergio, Juárez, Diana Luz, Guitart-Mampel, Mariona, González-Casacuberta, Ingrid, Canto-Santos, Judith, Lozano, Ester, León, Agathe, Pedrol, Enric, Miró, Òscar, Tobías, Ester, Mallolas, Josep, Rojas, Jhon F., Cardellach, Francesc, Martínez, Esteban, Garrabou, Gloria“…Methods: We analyzed reasons for PEP discontinuation and main secondary effects of treatment withdrawal, mtDNA content from peripheral blood mononuclear cells and metabolic profile, before and after 28 days of PEP, in 23 patients classified depending on PEP composition: one protease inhibitor (PI) plus Zidovudine/Lamivudine (PI plus AZT + 3TC; n = 9) or PI plus Tenofovir/Emtricitabine (PI plus TDF + FTC; n = 14). …”
Publicado 2020
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118306por Goossens, E, Jahnukainen, K, Mitchell, RT, van Pelt, AMM, Pennings, G, Rives, N, Poels, J, Wyns, C, Lane, S, Rodriguez-Wallberg, KA, Rives, A, Valli-Pulaski, H, Steimer, S, Kliesch, S, Braye, A, Andres, MM, Medrano, J, Ramos, L, Kristensen, SG, Andersen, CY, Bjarnason, R, Orwig, KE, Neuhaus, N, Stukenborg, JB“…More than 1033 young patients (age range 3 months to 18 years) have already undergone testicular tissue retrieval and storage for fertility preservation. LIMITATIONS, REASONS FOR CAUTION: The review does not include the data of all reproductive centres worldwide. …”
Publicado 2020
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118307por Michalczyk, Małgorzata Magdalena, Gołaś, Artur, Maszczyk, Adam, Kaczka, Piotr, Zając, Adam“…Conclusion: Due to the serum level of 25(OH)D demonstrated by most participants at the beginning of the study and after summertime, all-year-round supplementation with high doses of vitamin D seems to be a reasonable solution to enhance high 25(OH)D concentration in blood and physical performance. …”
Publicado 2020
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118308por Duonamou, Lucie, Konate, Alexandre, Djègo Djossou, Sylvie, Mensah, Guy Apollinaire, Xu, Jiliang, Humle, Tatyana“…Only 10.8% reported consuming more domestic meat during the EVD outbreak compared with before; affordability and availability were the main reported reasons for why people did not consume more domestic meat and why two thirds reported consuming more fish. …”
Publicado 2020
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118309por Liu, Zhike, Zhang, Liang, Yang, Yu, Meng, Ruogu, Fang, Ting, Dong, Ying, Li, Ning, Xu, Guozhang, Zhan, Siyan“…BACKGROUND: Comprehensive safety data for vaccines from post-licensure surveillance, especially active surveillance, could guide administrations and individuals to make reasonable decisions on vaccination. Therefore, we designed a pilot study to assess the capability of a regional health care information platform to actively monitor the safety of a newly licensed vaccine. …”
Publicado 2020
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118310por Lee, Hsiu-An, Kung, Hsin-Hua, Udayasankaran, Jai Ganesh, Kijsanayotin, Boonchai, B Marcelo, Alvin, Chao, Louis R, Hsu, Chien-Yeh“…In the future, the PHR platform could be utilized for the purpose of precision and individual medicine in a cross-country manner because of the platform’s provision of a secure and efficient PHR sharing and management architecture, making it a reasonable base for future data collection sources and the data analytics needed for precision medicine.…”
Publicado 2020
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118311por Goisis, Alice, Håberg, Siri Eldevik, Hanevik, Hans Ivar, Magnus, Maria Christine, Kravdal, Øystein“…Additional adjustment for maternal education, marital status and area of residence did not further attenuate the associations. LIMITATIONS, REASONS FOR CAUTION: The data does not enable us to tell whether the lower numbers of children conceived through ART amongst more disadvantaged individuals is caused by lower success rates with ART treatment, lower demand of ART services or barriers faced in access to ART. …”
Publicado 2020
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118312“…Childhood experiences of physical and sexual abuse were individually associated with increased risk of miscarriage. LIMITATIONS, REASONS FOR CAUTION: Given the magnitude of the observed associations, their biological plausibility, temporal order and consistency with evidence suggesting a positive association between ACE and adverse reproductive outcomes, it is unlikely that our findings are spurious. …”
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118313por Faizal, W.M., Ghazali, N.N.N., Khor, C.Y., Badruddin, Irfan Anjum, Zainon, M.Z., Yazid, Aznijar Ahmad, Ibrahim, Norliza Binti, Razi, Roziana Mohd“…In addition, it assisted in making strategic and reasonable decision regarding the adoption of treatment methods in clinical settings. …”
Publicado 2020
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118314por Chen, Yangyi, Zhao, Zhimin, Fan, Haina, Li, Zhengxin, He, Yingchun, Liu, Chenghai“…This subset of patients typically presents with advanced liver fibrosis at baseline. Therefore, it is reasonable to administer the anti-fibrotic agents, coupled with antivirals for patients with advanced liver fibrosis due to HBV, in order to improve the fibrotic regression of the patients. …”
Publicado 2020
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118315“…The internet is a readily accessible source of information to explain the reasons for these changes to the public. It is important that web-based health information about changes to national screening programs is accessible and understandable for the general population. …”
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118316por Hult, Sara, Sartori, Daniele, Bergvall, Tomas, Hedfors Vidlin, Sara, Grundmark, Birgitta, Ellenius, Johan, Norén, G. Niklas“…Of these, 157 drug pairs were considered already known to interact, whereas 232 were closed after preliminary assessment for other reasons. Ten drug pairs were subjected to in-depth signal assessment and an additional eight were decided to be kept under review awaiting additional reports. …”
Publicado 2020
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118317por Berkhout, Robbert P, Keijser, Remco, Repping, Sjoerd, Lambalk, Cornelis B, Afink, Gijs B, Mastenbroek, Sebastiaan, Hamer, Geert“…Transcriptome analysis further demonstrated that this effect is very likely mediated via altered expression of genes involved in cell adhesion and cytoskeleton organization. LIMITATIONS, REASONS FOR CAUTION: The effect of hsa-miR-320a on hESCs was measured in vitro. …”
Publicado 2020
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118318por Jiang, Jing-Bo, Li, Jin-Yi, Jiang, Zhi-Yuan, Wang, An, Huang, Zheng, Xu, Hong-Yuan, Shu, Cheng-Lin, Li, Gui-Juan, Zheng, Yi-Sheng, He, Yan, Zhong, Guo-Qiang“…Maintaining the CF value between 3 and 10 g may be reasonable and effective for creating the necessary lesion size and reducing the risk of complications, such as steam pops and perforations.…”
Publicado 2020
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118319por Thomas, James S., Clark, Brian C., Russ, David W., France, Christopher R., Ploutz-Snyder, Robert, Corcos, Daniel M.“…IMPORTANCE: Low back pain (LBP) is one of the most common reasons for seeking medical care. Manual therapy is a common treatment of LBP, yet few studies have directly compared the effectiveness of thrust (spinal manipulation) vs nonthrust (spinal mobilization) techniques. …”
Publicado 2020
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118320por Ghosh, Shinjini“…Being able to analyse and predict the spread of this epidemic-causing disease is hence of utmost importance now, especially as it would help in the reasoning behind important decisions drastically affecting countries and their people, as well as in ensuring efficient resource and utility management. …”
Publicado 2020
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