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  1. 118761
    “…BACKGROUND: Long-standing knee pain is one of the most common reasons for adolescents (aged 10-19 years) to consult general practice. …”
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    Exploring User Visions for Modeling mHealth Apps Toward Supporting Patient-Parent-Clinician Collaboration and Shared Decision-making When Treating Adolescent Knee Pain in General Practice: Workshop Study
  2. 118762
    “…As the Th2 immune response is characterized by eosinophil mobilization to the target organ and release of their cationic granule proteins, it is reasonable to investigate if the degranulation of eosinophils could be associated with the local injury. …”
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    Eosinophil Granule Proteins Involvement in Acute Appendicitis—An Allergic Disease?
  3. 118763
    “…These findings suggest that statin initiation may be an effective and reasonable approach for preventing kidney disease in patients with type 2 DM.…”
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    Statin initiation and risk of incident kidney disease in patients with diabetes
  4. 118764
    “…CONCLUSIONS: In this proof-of-concept study, a clinical deterioration detection algorithm was developed and retrospectively evaluated to classify clinical stability and instability, achieving reasonable performance considering the heterogeneous population of neonates with cCHD. …”
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    Continuous Data-Driven Monitoring in Critical Congenital Heart Disease: Clinical Deterioration Model Development
  5. 118765
    “…Of the 171 participants who completed follow-up, only half (91/171, 53.2%) reported using the same phone as that used at enrollment, with the CareConekta app still installed on the phone and GPS usually enabled. The top reasons reported for the lack of heartbeat data were not having mobile data, uninstalling the app, and no longer having a smartphone. …”
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    The Implementation of a GPS-Based Location-Tracking Smartphone App in South Africa to Improve Engagement in HIV Care: Randomized Controlled Trial
  6. 118766
    “…Our findings suggest that for modest levels of comorbidities, this assumption is reasonable. Thus, trial efficacy findings can be combined with data on natural history and competing risks to assess the likely overall benefit of treatments in the context of comorbidity.…”
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    Treatment effect modification due to comorbidity: Individual participant data meta-analyses of 120 randomised controlled trials
  7. 118767
    “…Only two supplements were tested in a good quality clinical trial. LIMITATIONS, REASONS FOR CAUTION: As a consequence of searching shopping websites, a comprehensive search strategy could not be formulated. …”
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    The lack of evidence behind over-the-counter antioxidant supplements for male fertility patients: a scoping review
  8. 118768
    “…Convenience and access were the primary reasons for preferring online delivery. To improve online delivery, future yoga studies should include specific activities for fostering group engagement, enhancing safety protocols, and increasing technical support. …”
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    Acceptability of Online Yoga Among Individuals With Chronic Conditions and Their Caregivers: Qualitative Study
  9. 118769
    por Zhou, Meng, Zhang, Ya-Min, Li, Tao
    Publicado 2023
    “…This is due to various reasons, including knowledge and attitudes of caregivers, patients, and health providers toward genetic testing. …”
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    Knowledge, attitudes and experiences of genetic testing for autism spectrum disorders among caregivers, patients, and health providers: A systematic review
  10. 118770
    “…The AFC was also decreased in patients with cancer (WMD = −0.93, 95% CI = −1.79 to −0.07, P = 0.033) compared to controls, while inhibin B and basal FSH levels showed no statistically significant differences. LIMITATIONS, REASONS FOR CAUTION: Serum AMH and basal FSH levels in this meta-analysis showed high heterogeneity, and the small number of studies contributing to most subgroup analyses limited the heterogeneity analysis. …”
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    Ovarian reserve in reproductive-aged patients with cancer before gonadotoxic treatment: a systematic review and meta-analysis
  11. 118771
    “…After adjusting for potential confounders, the probability of delayed health-seeking ≥4 weeks after symptom onset did not differ significantly by gender (44.0% and 36.2%, p = 0.14). While the top reasons for delayed healthcare-seeking were largely similar by gender, men were more likely to report initially perceiving their symptoms as not being serious (94.8% and 78.7%, p = 0.032), while women were more likely to report not knowing the symptoms of TB before their diagnosis (89.5% and 74.4%; p = 0.007) and having a prior bad healthcare experience (26.4% and 9.9%; p = 0.036). …”
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    A mixed methods study on men’s and women’s tuberculosis care journeys in Lusaka, Zambia—Implications for gender-tailored tuberculosis health promotion and case finding strategies
  12. 118772
    “…Moreover, there was a significant multiplicative interaction between BMI and lutein + zeaxanthin intake (P interaction <0.05). LIMITATIONS, REASONS FOR CAUTION: The cases and controls were not a random sample of the entire target population, which could lead to admission rate bias. …”
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    Phytochemical consumption and the risk of teratozoospermia: findings from a hospital-based case–control study in China
  13. 118773
    “…RESULTS: [(225)Ac]Ac-DOTA-JR11 has been successfully prepared and obtained in high radiochemical yield (RCY; 95%) and radiochemical purity (RCP; 94%). [(225)Ac]Ac-DOTA-JR11 showed reasonably good stability in PBS (77% intact radiopeptide at 24 h after incubation) and in mouse serum (~ 81% intact radiopeptide 24 h after incubation). [(177)Lu]Lu-DOTA-JR11 demonstrated excellent stability in both media (> 93%) up to 24 h post incubation. …”
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    First preclinical evaluation of [(225)Ac]Ac-DOTA-JR11 and comparison with [(177)Lu]Lu-DOTA-JR11, alpha versus beta radionuclide therapy of NETs
  14. 118774
    “…There is a large disparity between European countries with worse results observed for the Central and Eastern Europe (CEE) patients. One of the main reasons for this ineffectiveness is therapeutic inertia related to the limited access to appropriate therapy and suitable dosage intensity. …”
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    Regional differences in physicians’ behavior and factors influencing the intensity of PCSK9 inhibitor therapy with alirocumab: a subanalysis of the ODYSSEY APPRISE study
  15. 118775
    por Siraco, Susan, Bitter, Cindy, Chen, Tina
    Publicado 2022
    “…Although we chose to implement GRIEV_ING at our institution, other structured approaches (such as SPIKES) are reasonable as well. Each simulation case was conducted using a high-fidelity mannequin capable of intubation, respiratory examination findings such as abnormal breath sounds, and dynamic vital sign changes. …”
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    Breaking Bad News in the Emergency Department
  16. 118776
    “…This method provides a reasonable and effective scheme for the treatment of clinical refractory wounds.…”
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    The clinical application effects of artificial dermis scaffold and autologous split‐thickness skin composite grafts combined with vacuum‐assisted closure in refractory wounds
  17. 118777
    “…Research on these interventions among adolescents has frequently lacked detailed time-related attrition data alongside analysis of attrition reasons through usage. OBJECTIVE: The objective was to obtain daily attrition rates among adolescents in an mHealth intervention to gain a deeper understanding of attrition patterns, including the role of motivational support, such as altruistic rewards, through analysis of app usage data. …”
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    Usage and Daily Attrition of a Smartphone-Based Health Behavior Intervention: Randomized Controlled Trial
  18. 118778
    por Schreiber, Mike, Dohle, Simone
    Publicado 2023
    “…However, research is needed to understand the reasons for the difference in intervention effects between the early and delayed intervention groups. …”
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    A Smartphone-Based Implicit Theories Intervention for Health Behavior Change: Randomized Trial
  19. 118779
    “…The panels agreed that the draft architectural framework and hypothetical algorithm were reasonable. The system was not linked to electronic nursing records to protect patient privacy. …”
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    New Web-Based System for Recording Public Health Nursing Practices and Determining Best Practices: Protocol of an Exploratory Sequential Design
  20. 118780
    “…It is, however, difficult to quantify the real contribution of the interactive components, as the control group also had access to a limited version of the intervention for ethical reasons. Both groups were satisfied with the intervention they received, with the intervention study arm significantly more so than the control study arm. …”
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    Effectiveness of the SAFE eHealth Intervention for Women Experiencing Intimate Partner Violence and Abuse: Randomized Controlled Trial, Quantitative Process Evaluation, and Open Feasibility Study
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