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  1. 119301
    “…The level of mosaicism in lymphocytes, buccal cells or urine-derived cells was not predictive for mosaicism in ovarian cells. LIMITATIONS, REASONS FOR CAUTION: The results are based on a small number (n = 5) of TS patient samples but provide evidence that the majority of oocytes have a normal X chromosomal content and that follicles from the same patient can differ with respect to the level of mosaicism of their granulosa cells. …”
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    Ovarian follicles of young patients with Turner’s syndrome contain normal oocytes but monosomic 45,X granulosa cells
  2. 119302
    “…Only the model for minimal–mild endometriosis (Model 2: hsa-miR-125b-5p, hsa-miR-28-5p and hsa-miR-29a-3p) had diagnostic power above chance performance in the independent validation (AUC = 60%) with an acceptable sensitivity (78%) but poor specificity (37%). LIMITATIONS, REASONS FOR CAUTION: The diagnostic models were built and tested for validation in two patient cohorts from a single tertiary endometriosis centre. …”
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    Plasma miRNAs as biomarkers for endometriosis
  3. 119303
    “…Participant expectations indicate that they believed the program to be beneficial for them (131/133, 98.5%) and provide a feeling of support (119/133, 89.5%). Reasons for study participation were insufficient outpatient health care (83/133, 62.4%) and flexibility regarding time (106/133, 79.7%) and location (109/133, 82.0%). …”
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    An Internet-Based Self-Help Intervention for Skin Picking (SaveMySkin): Pilot Randomized Controlled Trial
  4. 119304
    “…DISCUSSION/SIGNIFICANCE OF IMPACT: Childhood disruptive behaviors are among the most frequent reasons for referral to outpatient child/adolescent mental health clinics (Sukhodolsky et al., 2016). …”
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    2465 Enhancing outcomes for young children with behavior disorders: A model for coordinated care
  5. 119305
    “…OBJECTIVES/SPECIFIC AIMS: Immigrants to North America receive more interventions at end of life.The reasons for this are not entirely clear but may potentially be due to knowledge gaps. …”
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    3095 Perceived Knowledge of Palliative Care among Immigrants: A Secondary Data Analysis from the Health Information National Trends Survey
  6. 119306
    “…Ten women who suffered relapse died due to breast cancer. LIMITATIONS, REASONS FOR CAUTION: This is reassuring data; however, the result is based on a few cases. …”
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    No increased risk of relapse of breast cancer for women who give birth after assisted conception
  7. 119307
    “…In subsequent experiment, we observed that 100 ng/mL leptin significantly modulated FOXL2 and RSPO1 expression in cultured granulosa cells harvested from large hierarchical and small prehierarchical follicles. These findings reasonably suggest that FOXL2 and RSPO1 genes may have a role in modulating the ovarian mechanisms, possibly affecting follicle growth and selection in laying hens. …”
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    Expression of FOXL2 and RSPO1 in Hen Ovarian Follicles and Implication of Exogenous Leptin in Modulating Their mRNA Expression in In Vitro Cultured Granulosa Cells
  8. 119308
    “…Lipids, glucose tolerance indices and cortisone were not related to growth. LIMITATIONS, REASONS FOR CAUTION: This study is of modest size and of observational nature, and we did not include a control group. …”
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    Increased blood pressure and impaired endothelial function after accelerated growth in IVF/ICSI children
  9. 119309
    “…Participants with FSD were further asked to indicate whether or not they sought help for their conditions, the reasons they sought help, and the types of help they sought. …”
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    “I did not know it was a medical condition”: Predictors, severity and help seeking behaviors of women with female sexual dysfunction in the Volta region of Ghana
  10. 119310
    por ÖZMERT, Emin, ARSLAN, Umut
    Publicado 2020
    “…Although the long-term adverse effects are still unknown, as an extraocular approach, subtenon implantation of the stem cells seems to be a reasonable way to avoid the devastating side effects of intravitreal/submacular injection. …”
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    Management of retinitis pigmentosa by Wharton’s jelly derived mesenchymal stem cells: preliminary clinical results
  11. 119311
    “…Ultrastructural analysis of spermatozoa in the patient with the C7orf61 mutation revealed a mixture of round heads with no acrosomes (globozoospermia) and ovoid or irregular heads with small acrosomes frequently detached from the sperm head (acrosomal hypoplasia). LIMITATIONS, REASONS FOR CAUTION: Stringent filtering criteria were used in the exome data analysis which could result in possible pathogenic variants remaining undetected. …”
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    Exome sequencing reveals novel causes as well as new candidate genes for human globozoospermia
  12. 119312
    “…We noted a very strong effect of clinic site on both LBR and BW, thus confounding between treatment practices and clinic site may have masked the effect of culture conditions. LIMITATIONS, REASONS FOR CAUTION: Larger datasets with more inter-centre variation are also needed, with key embryo culture variables comprehensively recorded in national treatment registries. …”
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    The impact of selected embryo culture conditions on ART treatment cycle outcomes: a UK national study
  13. 119313
    “…The performance of the different metrics varied slightly across the fractions of each patient, which indicates that weekly contour propagation models provide a reasonable approximation of the daily contour propagation models. …”
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    Evaluation of a commercial DIR platform for contour propagation in prostate cancer patients treated with IMRT/VMAT
  14. 119314
    “…When continuous therapy is not appropriate due to patient choice or toxicities, an efficacious (not limited to thalidomide and bortezomib) but tolerable first line FDT strategy, which can maximise TFI and maintain a good QoL, remains a reasonable alternative approach.…”
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    Treatment-free interval as an additional measure of efficacy in a large UK dataset of transplant ineligible myeloma patients
  15. 119315
    “…With respect to costs, women were willing to pay €1000 instead of no costs for a decrease in OHSS rate of 5.4%. LIMITATIONS, REASONS FOR CAUTION: The sample size of our study is relatively small which may limit the generalizability and sensitivity of the study. …”
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    The perspective of women with an increased risk of OHSS regarding the safety and burden of IVF: a discrete choice experiment
  16. 119316
    “…Thematic analysis of chart board discussions at both meetings revealed the joint goals of CRRAB and reasons for and barriers to patient engagement. Results In 2016, 21 individuals participated and self-identified as patients (11, 52%), healthcare professionals (6, 29%), and/or researchers (7, 33%) (participants could overlap stakeholder groups). …”
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    The Canadian retinoblastoma research advisory board: a framework for patient engagement
  17. 119317
    “…Among the underlying conditions, pelvic floor tenderness (as a marker of pelvic floor myalgia) was associated with CHC ineffectiveness. LIMITATIONS AND REASONS FOR CAUTION: This study involved patient recall and no longitudinal follow-up. …”
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    CHC for pelvic pain in women with endometriosis: ineffectiveness or discontinuation due to side-effects
  18. 119318
    “…In clinical practice, the prognosis of liver cancer patients is poor, and the complex reasons contribute to treatment failures, including fibrosis, hepatitis viral infection, drug resistance and metastasis. …”
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    Downregulation of orosomucoid 2 acts as a prognostic factor associated with cancer-promoting pathways in liver cancer
  19. 119319
    “…Based on these findings, increasing daily fibre intake by 15 g or to 35 g might be a reasonable target that would be expected to reduce risk of premature mortality in adults with diabetes.…”
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    Dietary fibre and whole grains in diabetes management: Systematic review and meta-analyses
  20. 119320
    “…Most identified genes are known to be related to biological processes of puberty; however, genetic polymorphisms of only four of these genes were previously linked to pubertal markers in humans. LIMITATIONS, REASONS FOR CAUTION: The relative age of pubertal onset to the age of DNAm measurements does not allow causal inference, since DNAm at an earlier age may have affected the pubertal age or pubertal age may have altered later DNAm. …”
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    Age at onset of different pubertal signs in boys and girls and differential DNA methylation at age 10 and 18 years: an epigenome-wide follow-up study
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