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  1. 119881
    “…ATM, BRCA1, TP53, TP63, TP73, and BUB1B). LIMITATIONS, REASONS FOR CAUTION: Using mature oocytes instead of GV-stage oocytes discarded from ICSI treatments may provide different results. …”
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    Longevity pathways are associated with human ovarian ageing
  2. 119882
    “…Preterm birth was less common among multiparous women and women with ‘male factor’ as treatment indication (compared to ‘tubal factor’). LIMITATIONS, REASONS FOR CAUTION: Due to the retrospective nature of our study, we cannot prove causality. …”
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    Effect of parental and ART treatment characteristics on perinatal outcomes
  3. 119883
    “…CONCLUSIONS: For acquiring IHD, we judged the existing body of evidence from human data to provide “limited evidence of harmfulness”; a positive relationship is observed between exposure and outcome where chance, bias, and confounding cannot be ruled out with reasonable confidence. For all other included outcomes, the bodies of evidence were judged as “inadequate evidence of harmfulness”. …”
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    The effect of occupational exposure to noise on ischaemic heart disease, stroke and hypertension: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-Related Burden of Disease and Injury
  4. 119884
    “…The second- and third-trimester uterine artery indices in pregnancies after fresh ET were comparable to those in pregnancies after natural conception. LIMITATIONS, REASONS FOR CAUTION: The main limitation of this study is the lack of power to optimally detect differences in placental development and placenta-related pregnancy outcomes between pregnancies after different modes of conception. …”
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    The influence of frozen-thawed and fresh embryo transfer on utero-placental (vascular) development: the Rotterdam Periconception cohort
  5. 119885
    por Wright, Rick, Wright, Rick
    Publicado 2021
    “…OBJECTIVES: Revision ACL reconstruction has been documented to have inferior outcomes compared with primary ACL reconstructions. The reasons why remain unknown. The purpose of this study was to determine if surgical factors performed at the time of revision ACL reconstruction have the ability to influence a patient’s outcome at 6-year follow-up. …”
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    Surgical Predictors of Clinical Outcome Six Years following Revision ACL Reconstruction
  6. 119886
    “…These observations will guide the development of a patient survey with the goal of obtaining qualitative data to explain the reasons for decreased utilization during the pandemic. …”
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    Healthcare Utilization Among Children and Adolescents with Sickle Cell Disease during the COVID-19 Pandemic
  7. 119887
    “…We excluded patients admitted for reasons other than SARS-CoV-2 infection and reviewed only the in-hospital experience. …”
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    Impact of Sickle Cell Trait on Morbidity and Mortality from Sars-Cov-2 Infection
  8. 119888
    “…Assuming a monetary value of €55 000 or more, gonadotrophins had the highest probability of maximally 56% to achieve the highest net benefit. LIMITATIONS, REASONS FOR CAUTION: Our model focused on population level and was thus based on average costs for the average number of four cycles conducted. …”
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    Cost-effectiveness of ovarian stimulation agents for IUI in couples with unexplained subfertility
  9. 119889
    “…Items focused on specifying the “Nature of the Desired Action” were adhered to most commonly—feedback was often presented in the context of an external priority (13/17), showed or described a discrepancy in performance (14/17), and in all cases it was reasonable for the recipients to be responsible for the change in behavior (17/17). …”
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    How well do critical care audit and feedback interventions adhere to best practice? Development and application of the REFLECT-52 evaluation tool
  10. 119890
    “…Intriguingly, the distribution of embryonic chromosome abnormalities was more frequent on autosomes 22 (20.39%), 21 (18.45%) and 16 (17.47%), compared with the X chromosome (8.73%). LIMITATIONS, REASONS FOR CAUTION: Selection bias is an inherent drawback of a retrospective study. …”
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    Preimplantation genetic testing is not a preferred recommendation for patients with X chromosome abnormalities
  11. 119891
    “…However, age had a positive relationship with the presence of male microchimerism (P = 0.02). LIMITATIONS, REASONS FOR CAUTION: After stratifying for variables of interest, some participant groups resulted in a low numbers of subjects. …”
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    Male microchimerism in females: a quantitative study of twin pedigrees to investigate mechanisms
  12. 119892
    “…LARGE SCALE DATA: N/A. LIMITATIONS, REASONS FOR CAUTION: This was a preliminary study performed with mouse ovarian samples. …”
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    The cyto-protective effects of LH on ovarian reserve and female fertility during exposure to gonadotoxic alkylating agents in an adult mouse model
  13. 119893
    “…LARGE SCALE DATA: The datasets for the Italian cohort generated during the current study are publicly available at ClinVar database (http://www.ncbi.nlm.nih.gov/clinvar/): accession numbers SCV001364312 to SCV001364375. LIMITATIONS, REASONS FOR CAUTION: This is a targeted WES analysis hunting variants in candidate genes previously identified by different genomic approaches. …”
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    Targeted whole exome sequencing and Drosophila modelling to unveil the molecular basis of primary ovarian insufficiency
  14. 119894
    “…The second was an NHL player that retired for reasons unrelated to his shoulder, despite a good clinical outcome and a healed repair on post-operative imaging. …”
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    Return to Play After Arthroscopic Management of Rotator Cuff Tears in Professional Contact Athletes (245)
  15. 119895
    “…For both clinical (e.g. testing isotonic strength in patients with frank weakness yields unreliable strength measurements and provides little useful information) and ethical (e.g. to avoid causing pain to patients already experiencing significant shoulder pain) reasons, this study evaluating dynamic strength testing was strictly limited to patients with negative traditional, static PE tests. …”
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    The Association between Radiologic Severity of Rotator Cuff Pathology and Supraspinatus Weakness on Biomechanical Assessment (229)
  16. 119896
    “…METHODS: PRO endpoints evaluated through 48 weeks of therapy included treatment satisfaction (HIV Treatment Satisfaction Questionnaire [HIVTSQ]), treatment acceptance (“General Acceptance” domain of the Chronic Treatment Acceptance [ACCEPT(®)] questionnaire), acceptability of injections (Perception of Injection [PIN] questionnaire), treatment preference (questionnaire), and reasons for switching to/continuing long-acting therapy (exploratory endpoint; questionnaire). …”
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    Patient-Reported Outcomes Through 1 Year of an HIV-1 Clinical Trial Evaluating Long-Acting Cabotegravir and Rilpivirine Administered Every 4 or 8 Weeks (ATLAS-2M)
  17. 119897
    “…Sharing statement: Data will be made available after the main trial analyses have been completed on reasonable request from researchers with ethics approval and a clear protocol. …”
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    The Positive Choices trial: study protocol for a Phase-III RCT trial of a whole-school social marketing intervention to promote sexual health and reduce health inequalities
  18. 119898
    “…Pritelivir was well tolerated without significant adverse effects.Reasons for incomplete lesion resolution during the 28 day treatment period, were extensive lesions in one patient, one patient with resistance development, and one patient with lesions in the oral cavity. …”
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    1060. Pritelivir in Immunocompromised Patients with Mucocutaneous Acyclovir-Resistant Herpes Simplex Virus-Infections – First Case Series
  19. 119899
    “…For patients with non-severe infection, the reasons for hospitalization were dehydration and tachycardia requiring intravenous fluids. …”
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    COVID-19 in Children, Adolescents and Young Adults with Hematological Malignancies
  20. 119900
    “…LARGE SCALE DATA: The age- and BMI-adjusted GWAS meta-analysis summary statistics are available for download from the GWAS Catalog with accession numbers GCST90044902 and GCST90044903. LIMITATIONS, REASONS FOR CAUTION: The main limitation was the low prevalence of PCOS in registers; however, the ones with the diagnosis most likely represent the most severe cases. …”
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    Leveraging Northern European population history: novel low-frequency variants for polycystic ovary syndrome
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