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  1. 292461
    “…Mechanistically, L-5-HTP inhibited IFN-γ-induced expression of RTK ligands and thus suppressed phosphorylation-mediated activation of RTK receptors and the downstream MEK/ERK/c-JUN signaling cascade, leading to decreased PD-L1 induction. …”
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    L-5-hydroxytryptophan promotes antitumor immunity by inhibiting PD-L1 inducible expression
  2. 292462
    “…Fc region binds to different receptors on the surface of various immune cells, dictating the type of immune response. …”
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    IgG N-glycome changes during the course of severe COVID-19: An observational study
  3. 292463
    “…BACKGROUND: Toll-like receptors (TLRs) are critical innate immune sensors that elicit antitumor immune responses in cancer immunotherapy. …”
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    Intratumoral immunotherapy using a TLR2/3 agonist, L-pampo, induces robust antitumor immune responses and enhances immune checkpoint blockade
  4. 292464
    “…Interleukins (ILs)/interleukin receptors (ILRs) interaction plays important roles in the antitumor immune response. …”
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    Low IL7R Expression at Diagnosis Predicted Relapse in Adult Acute Myeloid Leukemia Patients With t(8;21)
  5. 292465
    “…Moreover, several pieces of evidence suggest that SARS-CoV-2 infects various organs of the body via angiotensin-converting enzyme 2 (ACE2) receptors including bone cells (osteoblasts—OBs and osteoclasts—OCs). …”
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    Long-term implications of COVID-19 on bone health: pathophysiology and therapeutics
  6. 292466
    “…BACKGROUND: Nowadays, immunotherapy targeting immune checkpoint receptors is one of the cornerstones of systemic treatment in melanoma. …”
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    Homologous recombination repair gene mutations as a predictive biomarker for immunotherapy in patients with advanced melanoma
  7. 292467
    “…Adenosine activates adenosine A(2A) and A(2B) receptors on immune cells constituting one of the strongest immunosuppressive mediators. …”
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    Protein kinase inhibitor ceritinib blocks ectonucleotidase CD39 – a promising target for cancer immunotherapy
  8. 292468
    “…The hypothalamus, pituitary gland, and possibly adrenal glands are the targets of SARS-CoV-2 because of its angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) receptors expression. Hypocortisolemia can be seen in the postinfection period. …”
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    Is There Any Correlation between Baseline Serum Cortisol Levels and Disease Severity in PCR-Positive COVID-19 Patients with and without Diabetes Mellitus?
  9. 292469
    “…At the time of diagnosis, the predominance was in stage I: 36.48% and II 30.06%, with positive hormone receptors in 1,424 (89.96%) cases. The predominant treatments were hormonal (61.54%) and target directed with 30.85% for HER2(+) and 39.14% for HER2(−) accompanied in most cases (85.9%) by some period of chemotherapy. …”
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    Developing a real-world database for oncology: a descriptive analysis of breast cancer in Argentina
  10. 292470
    “…They are multi-host pathogens and cross-species infection is facilitated by the fact that viral entry is mediated by cellular Fc receptors recognizing antibody-coated viruses. We developed a pan-amdoparvovirus PCR and screened tissue samples from 666 wild carnivores (families Felidae, Canidae, and Mustelidae) from Newfoundland or Labrador (Canada) and molecularly characterized the identified strains. …”
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    Multi-host dispersal of known and novel carnivore amdoparvoviruses
  11. 292471
    “…The mRNA expression of bone morphogenetic proteins (BMPs), including BMP-2, BMP-3, BMP-4, BMP-6, BMP-7, as well as their receptors: BMPR-IA, BMPR-IB and BMPR-II was also determined. …”
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    Comparison of Selected Non-Coding RNAs and Gene Expression Profiles between Common Osteosarcoma Cell Lines
  12. 292472
    “…In this application, injectable filters obtained by injecting cationic hydroxyethylcellulose (HEC +) would impede the flow of toluene and copper ions partitioned in it, protecting downstream receptors. Co-contaminants can be subsequently extracted upstream of the filters (using pumping wells), to enable their simultaneous removal from aquifers.…”
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    Decontamination of water co-polluted by copper, toluene and tetrahydrofuran using lauric acid
  13. 292473
    “…CONCLUSION: Our study revealed that IQGAP1-shRNA was able to preserve hepatocyte integrity and the liver histological architecture through the regulation of the expression of IQGAPs, Ras, TRAILs and IL-8 receptors, as well as of pro-apoptotic and anti-apoptotic genes. …”
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    Inhibition of induced-hepatic cancer in vivo through IQGAP1-shRNA gene therapy and modulation of TRAIL-induced apoptosis pathway
  14. 292474
    “…Besides, NGF binding to TrkA receptors encouraged the intracellular Warburg effect in PC and DRG cells. …”
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    Nerve Growth Factor (NGF) Encourages the Neuroinvasive Potential of Pancreatic Cancer Cells by Activating the Warburg Effect and Promoting Tumor Derived Exosomal miRNA-21 Expression
  15. 292475
    “…Caffeine may have an ergogenic impact during anaerobic exercise by facilitating central effects by antagonizing adenosine receptors, hence decreasing the detrimental effects of adenosine on neurotransmission, arousal, and pain perception. …”
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    Low and Moderate Doses of Caffeinated Coffee Improve Repeated Sprint Performance in Female Team Sport Athletes
  16. 292476
    por Kadakia, Natasha, Sadiq, Sobia
    Publicado 2022
    “…Lastly, somatostatin analogues have been shown to reduce prolactin levels due to the presence of somatostatin receptors in prolactinomas. A published case series (Sosa-Eroza et al.) showed 5 patients with DA resistance with two cases with reduction in tumor volume and prolactin level. …”
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    PMON106 Persistent Prolactin Levels in a Patient with Pituitary Adenoma
  17. 292477
    “…The diagnosis of ACTH secreting pheochromocytoma was reaffirmed after both octreoscan and dotatate PET CT showed the presence of somatostatin receptors in the rightadrenal mass. After 14 days with controlling treatment, the patient underwent successful right adrenalectomy. …”
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    ODP061 When cortisol and catecholamines combine in a severe endocrine condition
  18. 292478
    “…BACKGROUND: Proprotein convertase subtilisin/kexin type 9 (PCSK9) circulates as mature and furin-cleaved forms, which differ in their properties to degrade low-density lipoprotein (LDL) receptors. OBJECTIVES: In this study, we sought to investigate whether PCSK9 subtypes associate with atherosclerotic cardiovascular events. …”
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    Circulating Furin-Cleaved Proprotein Convertase Subtilisin/Kexin Type 9 Concentration Predicts Future Coronary Events in Japanese Subjects
  19. 292479
    por Patel, Janki M, Shah, Parth, Shah, Love S
    Publicado 2022
    “…SGLT2 inhibitors decrease serum glucose and increase glycosuria by binding to renal tubular SGLT2 receptors, and inhibiting reabsorption of glucose from urine in the proximal convoluted tubule. …”
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    LBSUN291 Fournier's Gangrene In A Diabetic Male Taking Dapagliflozin
  20. 292480
    “…Research shows C1q is a ligand for frizzled receptors (FZDs). FZD‐induced yes‐associated protein (YAP)/transcriptional co‐activator with PDZ‐binding motif (TAZ) alternate Wnt signaling activation induces connective tissue growth factor (CTGF) production and hepatic stellate cell (HSC) activation. …”
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    Complement complex 1 subunit q‐mediated hepatic stellate cell activation with connective tissue growth factor elevation is a prognostic factor for survival in rat and human chronic liver diseases
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