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292921por Cheng, Yao, Yang, Xinyan, Liang, Lichun, Xin, Hua, Dong, Xinyu, Li, Weidong, Li, Jie, Guo, Xiaoli, Li, Yue, He, Jian, Zhang, Chunbin, Wang, Weiqun“…Gene set enrichment analysis (GSEA) analysis revealed that CXCL3 was mainly enriched in the cell cycle, DNA replication, NOD-like receptors, NOTCH and transforming growth factor-β (TGF-β) Signal pathways. …”
Publicado 2023
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292922“…DISCUSSION: The biological consequences of MC activation in vivo are extremely complex, and in all probability relate to the release of various combinations of soluble and granular factors, as well as to the expression of appropriate receptors by neighbouring cells. The subsequent synthesis and release of cytokines such as TNF-α and IL-1 may well follow at specific stages after activation, or may be an induced cytokine response by adjacent macrophagic or fibroblastic cells. …”
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292923por Goussia, Anna, Simou, Nafsika, Zagouri, Flora, Manousou, Kyriaki, Lazaridis, Georgios, Gogas, Helen, Koutras, Angelos, Sotiropoulou, Maria, Pentheroudakis, George, Bafaloukos, Dimitrios, Markopoulos, Christos, Patsea, Helen, Christodoulou, Christos, Papakostas, Pavlos, Zaramboukas, Thomas, Samantas, Epaminontas, Kosmidis, Paris, Venizelos, Vasileios, Karanikiotis, Charisios, Papatsibas, George, Xepapadakis, Grigorios, Kalogeras, Konstantine T., Bamia, Christina, Dimopoulos, Meletios-Athanassios, Malamou-Mitsi, Vassiliki, Fountzilas, George, Batistatou, Anna“…The main objectives of the study were to investigate the immunohistochemical expression of vascular endothelial growth factor (VEGF) family ligands (VEGF-A and VEGF-C) and receptors (VEGFR1, VEGFR2 and VEGFR3) in breast cancer and their associations with clinicopathological parameters, cancer subtypes/subgroups and patient outcome. …”
Publicado 2018
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292924“…For example, research of low-density lipoprotein (LDL)-receptors in the rare disease known as familial hypercholesterolemia led to the discovery of statins, a drug therapy that is now used routinely to prevent heart disease. …”
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292925por Selvaggi, Pierluigi, Jauhar, Sameer, Kotoula, Vasileia, Pepper, Fiona, Veronese, Mattia, Santangelo, Barbara, Zelaya, Fernando, Turkheimer, Federico, Mehta, Mitul, Howes, Oliver“…Critically, clinical and pre-clinical evidence suggests that antipsychotics increase CBF, especially in the basal ganglia through dopamine D2 receptors blockade. Here, we assessed CBF differences between FEP and controls in a larger cohort of unmedicated or minimally treated patients. …”
Publicado 2020
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292926“…Findings from a histological case series suggest that SARS-CoV-2 can infect endothelial cells directly, possibly via endothelial ACE2 receptors, leading to inflammation in the endothelium. …”
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292927por Aghevlian, Sadaf, Cai, Zhongli, Hedley, David, Winnik, Mitchell A., Reilly, Raymond M.“…BACKGROUND: Epidermal growth factor receptors (EGFR) are overexpressed on > 90% of pancreatic cancers (PnCa) and represent an attractive target for the development of novel therapies, including radioimmunotherapy (RIT). …”
Publicado 2020
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292928por Khatami, Mahin“…Vaccination of the unborn is likely to disturb trophoblast‐embryo‐fetus‐placenta biology and orderly growth of embryo‐fetus, alter epithelial‐mesenchymal transition or constituent‐inducible receptors, damage mitochondria, and diverse function of histamine‐histidine pathways. …”
Publicado 2020
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292929por Ku, Anthony, Kondo, Misaki, Cai, Zhongli, Meens, Jalna, Li, Min Rong, Ailles, Laurie, Reilly, Raymond M.“…BACKGROUND: Epidermal growth factor receptors (EGFR) are overexpressed on many head and neck squamous cell carcinoma (HNSCC). …”
Publicado 2021
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292930por Fiebelkow, Jessica, Guendel, André, Guendel, Beate, Mehwald, Nora, Jetka, Tomasz, Komorowski, Michal, Waldherr, Steffen, Schaper, Fred, Dittrich, Anna“…Secreted cytokines bind to receptors within the membrane of their target cells. …”
Publicado 2021
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292931por Mahnashi, Mater H., Alqahtani, Yahya S., Alyami, Bandar A., Alqarni, Ali O., Ullah, Farhat, Wadood, Abdul, Sadiq, Abdul, Shareef, Azam, Ayaz, Muhammad“…Both compounds selectively binds with EGFR and HER2 receptors with low binding energies. Both compounds exhibited stronger interactions with VEGFR through binding pocket residues Lys868, Val916 and Asp1046. …”
Publicado 2021
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292932“…A predominância dos anticorpos Anti-D, Anti-E e Anti-Kell-1 nos receptores tem ligação direta com a imunogenicidade e a velocidade de indução da formação de anticorpos voltados contra esses antígenos. …”
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292933“…Visando a proteção dos doadores, receptores e profissionais da saúde, foram implementadas mudanças no fluxo de atendimento, classificação de risco, acolhimento ao doador, revisão dos critérios de triagem clínica e atualização de informações para a população geral. …”
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292934por Mir, Mohammad Muzaffar, Mir, Rashid, Alghamdi, Mushabab Ayed Abdullah, Alsayed, Badr Abdulmohsin, Wani, Javed Iqbal, Alharthi, Muffarah Hamid, AL-Shahrani, Abdullah M.“…The spike protein of SARS-CoV-2 efficiently binds to the angiotensin-converting enzyme 2 (ACE2) receptors and facilitates virus entry into the host cell. …”
Publicado 2021
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292935por Wang, Hongye, Yan, Dongshan, Li, Ya, Gong, Yanfei, Mai, Yulin, Li, Bingxiang, Zhu, Xiaoyong, Wan, Xinrui, Xie, Liyun, Jiang, HuaKe, Zhang, Min, Sun, Ming, Yao, Yufeng, Zhu, Yongzhang“…The clinical features, antibody responses targeting SARS-CoV-2 spike protein (S) and its different domains, SARS-CoV-2-specific Ig isotypes, IgG subclasses, ACE2 competitive antibodies, binding titers with FcγIIa and FcγIIb receptors, and 14 cytokines were comprehensively investigated. …”
Publicado 2022
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292936por Liang, Xue-Zhen, Luo, Di, Chen, Yan-Rong, Li, Jia-Cheng, Yan, Bo-Zhao, Guo, Yan-Bo, Wen, Ming-Tao, Xu, Bo, Li, Gang“…The GO and KEGG pathway enrichment analyses revealed that these 34 differentially expressed autophagy-related genes involved in SONFH were particularly enriched in death domain receptors, the FOXO signalling pathway and apoptosis. …”
Publicado 2022
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292937por XIE, Yang, ZHANG, Yi, SHI, Haizhu, WU, Zhaoju, YU, Xuehong, ZHANG, Chungu, FENG, Shun“…Molecularly imprinted polymers (MIPs) imitate interactions established by natural receptors to selectively retain a target molecule, like antibodies or antigens do. …”
Publicado 2022
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292938por Zhang, Bing, Zhang, Ying, Dang, Wenli, Xing, Bin, Yu, Changxiang, Guo, Pan, Pi, Jiaxin, Deng, Xiuping, Qi, Dongli, Liu, Zhidong“…However, the differences in the expression levels of these receptors on the tumor cell surface limit the clinical application of anti-tumor preparations modified by a single ligand. …”
Publicado 2022
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292939por Gellen, Barnabas, Thorin‐Trescases, Nathalie, Thorin, Eric, Gand, Elise, Ragot, Stephanie, Montaigne, David, Pucheu, Yann, Mohammedi, Kamel, Gatault, Philippe, Potier, Louis, Liuu, Evelyne, Hadjadj, Samy, Saulnier, Pierre‐Jean, Hadjadj, Samy, Marechaud, Richard, Ragot, Stéphanie, Piguel, Xavier, Saulnier, Pierre‐Jean, Javaugue, Vincent, Gand, Elise, Hulin‐Delmotte, Charlotte, Llatty, Pierre, Ducrocq, Gregory, Roussel, Ronan, Rigalleau, Vincent, Pucheu, Yann, Zaoui, Philippe, Montaigne, David, Halimi, Jean‐Michel, Gatault, Philippe, Sosner, Philippe, Gellen, Barnabas“…AIMS: The hyperglycaemic stress induces the release of inflammatory proteins such as S100A12, one of the endogenous ligands of the receptors for advanced glycation end products (RAGE). …”
Publicado 2022
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292940por Malm Tillgren, Sofia, Nieto-Fontarigo, Juan José, Cerps, Samuel, Ramu, Sangeetha, Menzel, Mandy, Mahmutovic Persson, Irma, Meissner, Anja, Akbarshahi, Hamid, Uller, Lena“…Pattern recognition receptors levels (TLR3, MDA5 and RIG-I) were measured in lung homogenates using RT-qPCR and western blot. …”
Publicado 2023
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