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281por Olsen, Jan Roger, Azeem, Waqas, Hellem, Margrete Reime, Marvyin, Kristo, Hua, Yaping, Qu, Yi, Li, Lisha, Lin, Biaoyang, Ke, XI- Song, Øyan, Anne Margrete, Kalland, Karl- Henning“…BACKGROUND: Expression of the androgen receptor (AR) is associated with androgen-dependent proliferation arrest and terminal differentiation of normal prostate epithelial cells. …”
Publicado 2016
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282por Freund, Jacquelyn, May, Rebecca M., Yang, Enjun, Li, Hongchuan, McCullen, Matthew, Zhang, Bin, Lenvik, Todd, Cichocki, Frank, Anderson, Stephen K., Kambayashi, Taku“…In this manuscript, we demonstrate that signals from activating receptors are critical for induction of Ly49 and KIR receptors during NK cell development; activating receptor-derived signals increased the probability of the Ly49 bidirectional Pro1 promoter to transcribe in the forward versus the reverse direction, leading to stable expression of Ly49 receptors in mature NK cells. …”
Publicado 2016
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283por Jorand, Raphael, Biswas, Sunetra, Wakefield, Devin L., Tobin, Steven J., Golfetto, Ottavia, Hilton, Kelsey, Ko, Michelle, Ramos, Joe W., Small, Alexander R., Chu, Peiguo, Singh, Gagandeep, Jovanovic-Talisman, Tijana“…A novel interaction specific to PDAC is identified between mu opioid receptor (MOR) and somatostatin receptor 2 (SSTR2). …”
Publicado 2016
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284“…Accumulation of glycine receptors at synapses requires the interaction between the beta subunit of the receptor and the scaffold protein gephyrin. …”
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285por Felce, James H., Latty, Sarah L., Knox, Rachel G., Mattick, Susan R., Lui, Yuan, Lee, Steven F., Klenerman, David, Davis, Simon J.“…The organization of Rhodopsin-family G protein-coupled receptors (GPCRs) at the cell surface is controversial. …”
Publicado 2017
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286“…G protein-coupled receptors (GPCRs) have been found to form heterodimers and modulate or fine-tune the functions of GPCRs. …”
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287“…The growth hormone receptor (GHR), although most well known for regulating growth, has many other important biological functions including regulating metabolism and controlling physiological processes related to the hepatobiliary, cardiovascular, renal, gastrointestinal, and reproductive systems. …”
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288por Critchley, William R., Pellet-Many, Caroline, Ringham-Terry, Benjamin, Harrison, Michael A., Zachary, Ian C., Ponnambalam, Sreenivasan“…Receptor tyrosine kinases (RTKs) are membrane-based sensors that enable rapid communication between cells and their environment. …”
Publicado 2018
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289“…This novel mechanism could help us to understand several observations, such as the critical role of delta opioid receptor regulation, the impact of delta opioid receptor binding site occupancy, and the participation of beta-arrestin2, in the development of morphine tolerance.…”
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290por Wang, Jinliang, Wang, Zilong, Liu, Renqiang, Shuai, Lei, Wang, Xinxin, Luo, Jie, Wang, Chong, Chen, Weiye, Wang, Xijun, Ge, Jinying, He, Xijun, Wen, Zhiyuan, Bu, Zhigao“…Here, we identified a novel receptor of RABV, which RABV uses to infect neurons. …”
Publicado 2018
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291por Guidolin, Diego, Marcoli, Manuela, Tortorella, Cinzia, Maura, Guido, Agnati, Luigi F.“…The discovery of receptor-receptor interactions (RRI) has expanded our understanding of the role that G protein-coupled receptors (GPCRs) play in intercellular communication. …”
Publicado 2019
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292por Rivers, Caroline A, Rogers, Mark F, Stubbs, Felicity E, Conway-Campbell, Becky L, Lightman, Stafford L, Pooley, John R“…Mineralocorticoid and glucocorticoid receptors (MRs and GRs) constitute a functionally important dual receptor system detecting and transmitting circulating corticosteroid signals. …”
Publicado 2019
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293por Amelirad, Asra, Shamsasenjan, Karim, Akbarzadehlaleh, Parvin, Pashoutan Sarvar, Davoud“…All cells encounter various signals coming from the surrounding environment and they need to receive and respond to these signals in order to perform their functions. Cell surface receptors are responsible for signal transduction .Platelets are blood cells which perform several functions using diverse receptors. …”
Publicado 2019
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294por Kawamura, Tomoe, Matsuura, Bunzo, Miyake, Teruki, Abe, Masanori, Ikeda, Yoshiou, Hiasa, Yoichi“…The administration of EM in this model promoted the effect of mosapride (a selective serotonin 5-hydroxytryptamine 4 (5-HT4) receptor agonist), and improved loperamide (a μ-opioid receptor agonist)-induced gastroparesis. …”
Publicado 2019
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295por de Souza, Ana Amélia, Altemani, Albina, de Araujo, Ney Soares, Texeira, Lucas Novaes, de Araújo, Vera Cavalcanti, Soares, Andresa Borges“…The aim of this study was to investigate the role of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER-2) in PA, RPA, and CXPA. …”
Publicado 2019
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296“…The presence of adiponectin receptors 1 and 2 (AdipoR1 and AdipoR2) as well as the leptin receptor (Ob-R) has been recognized in human adrenal tumors. …”
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297“…This review is focused on current knowledge about the activation and regulation of chemoattractant receptors. Emphasis is placed on the members of the N-formyl peptide receptor family, namely FPR (N-formyl peptide receptor), FPRL1 (FPR like-1) and FPRL2 (FPR like-2), and the complement fragment C5a receptors (C5aR and C5L2). …”
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298por Hanada, Takahisa“…It is widely accepted that glutamate-mediated neuronal hyperexcitation plays a causative role in eliciting seizures. Among glutamate receptors, the roles of N-methyl-D-aspartate (NMDA) and α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors in physiological and pathological conditions represent major clinical research targets. …”
Publicado 2020
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299por Sahoo, Bikash Ranjan“…Innate immunity driven by pattern recognition receptor (PRR) protects the host from invading pathogens. …”
Publicado 2020
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300“…The survival, growth, and mitotic activities of the GFLs are conveyed by a single receptor tyrosine kinase, Ret. The GFLs do not bind directly to Ret in order to activate it, and instead bind with high affinity to glycerophosphatidylinositol (GPI)-anchored coreceptors called the GDNF family receptor-αs (GFRαs). …”
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