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Mostrando 301 - 320 Resultados de 292,959 Para Buscar '"receptor"', tiempo de consulta: 0.84s Limitar resultados
  1. 301
    “…Here, we study the function of TPC1 and TPC2 for uptake, recycling, and degradation of epidermal growth factor receptor (EGFR) using a set of TPC knockout cells. …”
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    Two-pore channels affect EGF receptor signaling by receptor trafficking and expression
  2. 302
    “…Several intracellular trafficking pathways contribute to the regulation of AMPA receptor (AMPAR) levels at synapses and the control of synaptic strength. …”
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    VER/VEGF receptors regulate AMPA receptor surface levels and glutamatergic behavior
  3. 303
    “…GPR15 is a chemoattractant receptor that facilitates colon homing of regulatory and effector CD4(+) T cells in health and colitis. …”
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    The aryl hydrocarbon receptor regulates expression of mucosal trafficking receptor GPR15
  4. 304
    “…The plasminogen activation (PA) system plays a key role in cancer; it includes the serine-protease urokinase-type plasminogen activator (uPA). uPA binds to a specific cellular receptor (uPAR), which concentrates proteolytic activity at the cell surface, thus supporting cell migration. …”
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    The Urokinase Receptor: A Multifunctional Receptor in Cancer Cell Biology. Therapeutic Implications
  5. 305
    “…In ~70% of breast cancer (BC) cases, estrogen and progesterone receptors (ER and PR) are overexpressed, which can change during tumor progression. …”
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    Expression of Estrogen Receptor- and Progesterone Receptor-Regulating MicroRNAs in Breast Cancer
  6. 306
    por Frank, Filipp, Liu, Xu, Ortlund, Eric
    Publicado 2021
    Materias: “…Steroid Hormones and Receptors…”
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    Glucocorticoid Receptor Condensates Link DNA-Dependent Receptor Dimerization and Transcriptional Transactivation
  7. 307
    “…From this point of view, we noticed the correlation between serotonin receptor subtype 7 (5-HT(7)R) and NDDs including autism spectrum disorder (ASD), fragile X syndrome (FXS), and Rett syndrome (RTT). 5-HT(7)R modulators improved altered behaviors in animal models and also affected neuronal morphology via the 5-HT(7)R/G(12) signaling pathway. …”
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    Modulation of Serotonin Receptors in Neurodevelopmental Disorders: Focus on 5-HT7 Receptor
  8. 308
    “…The chemokine receptor CCR5 plays a vital role in immune surveillance and inflammation. …”
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    Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5
  9. 309
    “…Recent crystallography studies provided details of the binding of nonpeptide angiotensin receptor blockers (ARBs) to the Ang II type 1 (AT1) receptor, and these insights were applied to Ang II. …”
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    Receptor Interactions of Angiotensin II and Angiotensin Receptor Blockers—Relevance to COVID-19
  10. 310
    “…[Image: see text] Biased agonists, which selectively stimulate certain signaling pathways controlled by a G protein-coupled receptor (GPCR), hold great promise as drugs that maximize efficacy while minimizing dangerous side effects. …”
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    Delineating the Ligand–Receptor Interactions That Lead to Biased Signaling at the μ-Opioid Receptor
  11. 311
    “…Retinoic acid receptor-related orphan receptor-α (RORα) is a member of the orphan nuclear receptor family and functions as a transcriptional activator in response to circadian changes. …”
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    Unraveling the physiological roles of retinoic acid receptor-related orphan receptor α
  12. 312
    “…To begin to uncover the mechanisms underlying this variability, we screened the 11 most prevalent missense genetic variants in the oxytocin receptor (OXTR) gene. We found that five variants, V45L, P108A, L206V, V281M, and E339K, significantly altered oxytocin-induced Ca(2+) signaling or β-arrestin recruitment and proceeded to assess the effects of these variants on OXTR trafficking to the cell membrane, desensitization, and internalization. …”
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    Naturally Occurring Genetic Variants in the Oxytocin Receptor Alter Receptor Signaling Profiles
  13. 313
    “…Despite some advancements in anti-glioma therapies, patients’ prognosis remains poor. Toll-like receptors (TLRs) act as the first line of defense in the immune system being the detectors of those associated with bacteria, viruses, and danger signals. …”
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    Toll-like receptors and toll-like receptor-targeted immunotherapy against glioma
  14. 314
    por Zhao, Qi
    Publicado 2019
    “…T-cell interaction with a tumor cell is a critical event and primarily driven by T-cell receptor (TCR) recognition of peptide in the pocket HLA. …”
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    Novel chimeric antigen receptor T cells based on T-cell receptor-like antibodies
  15. 315
    “…Background: Presurgical treatment with an α-adrenergic receptor blocker is recommended to antagonize the catecholamine-induced α-adrenergic receptor mediated vasoconstriction in patients with pheochromocytoma or sympathetic paraganglioma (PPGL). …”
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    Influence of Receptor Polymorphisms on the Response to α-Adrenergic Receptor Blockers in Pheochromocytoma Patients
  16. 316
    “…In this review we will introduce G protein-coupled receptor 143 (GPR143), an enigmatic receptor in terms of classification within the GPCR superfamily and localization. …”
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    The Many Faces of G Protein-Coupled Receptor 143, an Atypical Intracellular Receptor
  17. 317
    “…Brain-derived Neurotrophic Factor (BDNF) binds to the TrkB tyrosine kinase receptor, which dictates the sensitivity of neurons to BDNF. …”
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    Transactivation of TrkB Receptors by Oxytocin and Its G Protein-Coupled Receptor
  18. 318
    “…Several S1PR therapeutic drugs have been developed to treat these diseases; however, they lack receptor subtype selectivity, which leads to side effects. …”
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    Structural basis for receptor selectivity and inverse agonism in S1P(5) receptors
  19. 319
    “…The orphan insulin receptor-related receptor (IRR) encoded by insrr gene is the third member of the insulin receptor family, also including the insulin receptor (IR) and the insulin-like growth factor receptor (IGF-1R). …”
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    Insulin Receptor-Related Receptor Regulates the Rate of Early Development in Xenopus laevis
  20. 320
    “…The nociceptin opioid receptor is a newly discovered member of the opioid receptor family with unique characteristics. …”
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    A Crosstalk between the Cannabinoid Receptors and Nociceptin Receptors in Colitis—Clinical Implications
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